<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08874

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMTNSTPIPTPAPSPSPLPPKDHTPEAAAAAADAEGGGGGGREGRVPERAAAEAVGEVDRGAEKRDEEGDHPMDGGGGGGGDGGPKPSPATVFRIRLKQPPASLRHKMSVPELCRNFSAVAWCGKLNAIACASETCARIPCSNASPPFWIPIHILNPERPTECAVFNVRADSPRDSVQFIEWSPRSCPRALLVANFHGRITIWTQPSQGPINLVRDASCWQCEHEWRQDLAVVTKWLSGMTPYRFLPNSSTSANSKSFEERFLPRQSQISVRWPNILCICSVFSSGSVQLHWAQWPSQNGSAPRWFSTSKGLLGAGPSGIMAADAIITESGALHVAGVPLVNPSTVVVWEVMPGPGNGFQTTAKISTTSSIPPYLSPPSWTGFAPLATYLFSLQEYLGSEGMQGKKPDHEITEAASIHCSPVSNFSAYVSPETAAQSATTTTWGSGVTAVAFDPTHGGSVIAVVIVEGQYMSPYDPDEGPSITGWRVQCWESSLQPVVLHPIFGNPSGSFGGQAPMQTVWETRVNKSIPPTDELRNPQAIASAPTVSDERNSSDCSVERATRLSFDPYDLPNDVRQLAQIVYSAHGGEVAVAFLRGGVHIFSGPDFNQIESYHVNVGSTIATPAFSSSSCCLASVWHDTVKDRTILKIIRVLPPALPIAHSRVSSAMWERAIADRFWWSLLAGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSTQHRQQHGPNLDRIKCRLLEGTNAQDVRALVLDMQARLLLDMLGKGIESALVNPSTLLAEPWQASSEMLSSIESDKMMVEPALAPSIQAYVDAILDLASHFITRLRRYASFCRTLASHAVGASAGTGSTRNMVTSPPHNSSSPSTNQGTQSGVTGATGNSQMQEWVQGAIAKISNNADGASTAAQNPISGRSSFIPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCLLFRKRQSSRIMINAQRTLDSNILKVQPIANGKLEDNGIAARPSLGVAKMEEVQSIRAGQLLPGAKGVDEGPPAKSVRLGFGNAGQGYTSEEVRVLFLILVDLCRRTAGSQHPLPASQVGASNIIIRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDADDLGPLDNMPKLKLSGLPNVEEAYDDYSGSQSLWPRKRRLSERDAAFGLKTSVGLGSYLGIMGSRRDVITAIWKTGLEGVWYKCIRCLRQTCAFAQPGSTGSAGSANEREAWWISRWTHGCPMCGGTWIRVV
Length1271
PositionTail
OrganismAnanas comosus (Pineapple) (Ananas ananas)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Bromeliaceae> Bromelioideae> Ananas.
Aromaticity0.07
Grand average of hydropathy-0.195
Instability index47.20
Isoelectric point6.47
Molecular weight136758.15
Publications
PubMed=27374615

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process
circadian regulation of gene expression	GO:0032922	IEA:EnsemblPlants
positive regulation of plant-type cell wall cellulose biosynthetic process	GO:2001011	IEA:EnsemblPlants
positive regulation of systemic acquired resistance	GO:1901672	IEA:EnsemblPlants
regulation of cell wall pectin metabolic process	GO:1902066	IEA:EnsemblPlants
regulation of ethylene-activated signaling pathway	GO:0010104	IEA:EnsemblPlants
regulation of jasmonic acid mediated signaling pathway	GO:2000022	IEA:EnsemblPlants
regulation of long-day photoperiodism, flowering	GO:0048586	IEA:EnsemblPlants
regulation of transcription, DNA-templated	GO:0006355	IEA:EnsemblPlants
response to osmotic stress	GO:0006970	IEA:EnsemblPlants
root development	GO:0048364	IEA:EnsemblPlants
trichome branching	GO:0010091	IEA:EnsemblPlants
trichome papilla formation	GO:1905499	IEA:EnsemblPlants









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08874
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.06|      15|      37|      35|      49|       1
---------------------------------------------------------------------------
   35-   49 (29.64/12.63)	GGGGGGR...EGRVPERA
   57-   74 (20.07/ 6.25)	VDRGAEKrdeEGDHPMDG
   75-   89 (30.35/13.10)	GGGGGGD...GGPKPSPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.15|      16|      19|     866|     883|       2
---------------------------------------------------------------------------
  848-  863 (27.45/11.09)	TRNMVTSPPHNSSSPS
  868-  883 (26.71/18.54)	TQSGVTGATGNSQMQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.96|      14|      19|     981|     997|       3
---------------------------------------------------------------------------
  981-  994 (24.57/18.70)	KLEDNGIAARP.SLG
 1014- 1028 (21.39/ 6.44)	KGVDEGPPAKSvRLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     224.43|      41|      41|     289|     329|       4
---------------------------------------------------------------------------
  202-  254 (44.41/17.84)	..WTQ.PSQGPinlvrD.AS...CWqcehewrqdlAVVTKWLSGMTPYRFLPNSSTSANS
  289-  329 (74.89/35.06)	LHWAQWPSQNG.....S.AP...RW..........FSTSKGLLGAGPSGIMAADAIITES
  332-  368 (52.06/22.16)	LHVAGVPLVNP.....StVV...VW..............EVMPGPG.NGFQTTAKISTTS
  371-  412 (53.07/22.73)	PPYLSPPSWTG.....F.APlatYL..........FSLQEYLGSEGMQG.KKPDHEITE.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.29|      40|      42|     107|     146|       5
---------------------------------------------------------------------------
  107-  146 (74.00/47.35)	MSVPELCRNFSAVAWCGKLNAIA.CASETCARIPCSNASPP
  147-  187 (70.29/44.55)	FWIPIHILNPERPTECAVFNVRAdSPRDSVQFIEWSPRSCP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     163.76|      43|      46|    1178|    1222|       6
---------------------------------------------------------------------------
  655-  687 (26.22/ 9.40)	....................LPIAHSRvssamweRAIADRFWWSLLA...GVdWWD
 1178- 1222 (69.29/45.85)	RLSERDAAFGLKTSVGLGsyLGIMGSR.......RDVITAIWKTGLE...GV.WYK
 1225- 1267 (68.25/38.91)	RCLRQTCAFAQPGSTGSA...GSANER.......EAWWISRWTHGCPmcgGT.W..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     138.57|      32|      37|     495|     531|       7
---------------------------------------------------------------------------
  420-  446 (37.62/11.16)	PVSNFSAYVSPETA.................AQSATTTTWGSGV...
  448-  491 (42.80/11.84)	AVAFDPTHG...GSViavvivegqymspydPDEGPSITGWRVQCWES
  495-  526 (58.14/28.85)	PVVLHPIFGNPSGSF...............GGQAPMQTVWETRVNKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.77|      17|      18|     720|     737|      12
---------------------------------------------------------------------------
  720-  737 (27.58/25.47)	TQHRQQHGPNLDrIKCRL
  741-  757 (27.19/18.88)	TNAQDVRALVLD.MQARL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.92|      15|      46|    1094|    1112|      13
---------------------------------------------------------------------------
 1094- 1112 (21.27/18.74)	LGPhMQNMPRPRgadAAGL
 1142- 1156 (28.65/12.08)	LGP.LDNMPKLK...LSGL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08874 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GTGSTRNMVTSPPHNSSSPSTNQGTQSGVTGATG
2) MTNSTPIPTPAPSPSPLPPKDHTPEAAAAAADAEGGGGGGREGRVPERAAAEAVGEVDRGAEKRDEEGDHPMDGGGGGGGDGGPKPSPATVFRIRLKQPP
3) VWETRVNKSIPPTDELRNPQAIASAPTVSD
844
1
518
877
100
547










Molecular Recognition Features






MoRF SequenceStartStop




1) GREGRVPERAAAEAVGE
2) PLPPKDHTPEAAAAAADAEGG
3) VFRIRLKQ
40
16
91
56
36
98