<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08865

Description Mediator of RNA polymerase II transcription subunit 33A
SequenceMAAAAAAWGAAAAEETKAAQEEGREPGLWAARVGAGMAAAGAALPHSPELAQLLAAHLGGGGGANAANPLAWKYAERALSSALASPLLLLSLLSTRVIRSRRLKPTAYRLYMELLRRHGFSFASQIKGPNFKRTMMLVDDNLQLSKIFGFQAYEPGVFIVAYVTCTLWQLLDAALDDEDLLELTPEKKAKWPTKPQDVSIIGERISNEPRVEHSEKLHKMNTKISVEIIGHFLRHKVISRLLCLARENMPSQWGSFASRLHLLATKSSALRNSTVSVQLFQRLIAGDWNILGKECKQNRKLEVRSLISFGSRTLGGYCLGASPSALWIPIDLYLEDCIDGSVAATNSIELLSGLVKTLQAVNGSTWHDAFLALWMASLRLVQRERDPHEGPVPRLDARLSMLLSITTLSIADIIEEDEALVDGMEVDSQLKDKAAGGKRCKDLVSSLQTLGDYESLLAPPPSIISAANQAAAKALMFVSGINVGGGYTENININDKALNCPGNLRHLIVEACISRNLLDTSAYFWPGYIAGRINQIPHSISSQLPGWSSFMKGAPLSQSMVNALVSNPAASLAELEKIFEIAINGSDDDKVSAATVLCGASLLRGWNIQEHTVRLVVKLLSPPVPPDYTGSDSHLINHGPMLNVLLTGISSVDCVQVFSFHGLVPALAAALMAICEVFGSCFPSVSRTLATGEEITAHAVFSNAFILLLRLWKFNHPPLEYCILGDGAPVGSQLTPEYLLLLRNARVLSPCKPAKNQAGHKAMSTDTSLPSPHPIFMDSFPKLKHWYRQHQACLASTLSGLVHGTPVHQNVDGLLRMMFRKINKGSNQSVGPVLSGSSSLSTSSGAGSDDTCVRPNLPAWDILEAVPFVVDAALAACSHGRLFPRELATGLKDLADFLPASLATIVSYFSAEVTRGVWKPAFMNGSDWPSPAANLSIVEEQIKKIVAATGGSFPATLPLPLAAFVSLTITYKLDKASERFLNLAGPALENLAASCPWPSMPIVAALWTQKVKRWSDFLVFSASRTVFHHNNDAVVQLLRSCFSATVGLSGTSSISGNGGIGSLLGHGFGSHFSGGLTPVAPGILYLRIYRCIKDVSILAEEILSLLMLSVKEIAETTVSKERSDRLKRTKHGMRYEQVSLAAAMTRVKVAAALGATFVWLSGGSRVVQSLIQEMLPSWFLSVHDLDQEGGSGPIVYMLGGYALAYFAVLSGMFAWGIDSTPVSKRRPRVVQSHFEFLASALDGKITLGCDWALWRAYVSGFLGLVVECAPSWVLEVGLDGLKRLSRGLRRWNEDELALALLRRGGVEAMGTAAELILAGE
Length1320
PositionTail
OrganismAnanas comosus (Pineapple) (Ananas ananas)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Bromeliaceae> Bromelioideae> Ananas.
Aromaticity0.07
Grand average of hydropathy0.145
Instability index42.74
Isoelectric point8.20
Molecular weight142318.68
Publications
PubMed=27374615

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08865
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     462.41|     147|     161|     997|    1155|       1
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  997- 1154 (223.14/151.83)	WPS..MPIVAALWTQKVKRWsdFLvfSASRTVFHHNNDAVVQLLRS.CFSATVGLSGTSSIS.GNGGIGSLLGHGFGSHFSgGLTPVAPGILYLriyRCikDVSILAEEILSLLMLSVkEIAETTVSKERSDRLKRTKHGM.RYEQVSLAAAMTRVKVAAALG
 1159- 1310 (239.27/129.21)	WLSggSRVVQSLIQEMLPSW..FL..SVHDLDQEGGSGPIVYMLGGyALAYFAVLSGMFAWGiDSTPVSKRRPRVVQSHFE.FLASALDGKITL...GC..DWALWRAYVSGFLGLVV.ECAPSWVLEVGLDGLKRLSRGLrRWNEDELALALLRRGGVEAMG
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.16|      31|      34|       1|      31|       2
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    1-   31 (54.53/25.99)	MAAAAAAWGAAAAEETKAAQ....EEGREPGLWAA
   33-   67 (49.63/23.04)	VGAGMAAAGAALPHSPELAQllaaHLGGGGGANAA
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.68|      20|      32|     434|     453|       3
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  434-  453 (35.62/19.88)	AAGGKRCKDL..VSSLQTLGDY
  466-  487 (29.06/14.94)	AANQAAAKALmfVSGINVGGGY
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.46|      14|      34|     705|     718|       4
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  705-  718 (28.37/18.38)	FILLLRLWKFNHP..P
  738-  753 (20.09/10.62)	YLLLLRNARVLSPckP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.78|      19|      36|      69|      87|       5
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   69-   87 (33.49/16.53)	PLAWK.YAE..RALSSALASPL
  105-  126 (27.29/12.34)	PTAYRlYMEllRRHGFSFASQI
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.22|      19|      36|     314|     334|       6
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  314-  334 (31.54/26.01)	LGGY..CLGASPSALWipIDLYL
  351-  371 (29.67/16.74)	LSGLvkTLQAVNGSTW..HDAFL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.20|      19|      36|     233|     253|       7
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  233-  253 (29.89/26.67)	LRHKVISrlLCLARENMPSQW
  270-  288 (32.31/21.44)	LRNSTVS..VQLFQRLIAGDW
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     256.66|      72|     216|     630|     704|       9
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  544-  600 (67.17/57.71)	...................LP..GWSSFM.KGA....PLS.QSMVNALvsnpAASLAELEKIF.....EIAINGSDDDKVSAATVLCGA
  630-  704 (122.47/129.20)	GSDSHLinhGPML...NVLLT..GISSVD.CVQ....VFSFHGLVPAL....AAALMAICEVFGSCFPSVSRTLATGEEITAHAVFSNA
  825-  890 (67.02/58.81)	GSNQSV...GPVLsgsSSLSTssGAGSDDtCVRpnlpAWDILEAVPFV....VDAALAACS.HGRLFP...RELATG............
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.50|      29|      29|     760|     788|      12
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  760-  788 (56.01/35.35)	HKA..MSTDTSLPSPHPIFMDSFPKLKHWYR
  790-  820 (46.49/28.03)	HQAclASTLSGLVHGTPVHQNVDGLLRMMFR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08865 with Med33 domain of Kingdom Viridiplantae
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