<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08835

Description Uncharacterized protein
SequenceMSKFPGHTNHPRGAFPQYPPGSGPGQGQGGQSGQINNGLGQGPPMPGRMGFNTGRVTGPPSMGYHSGNQGQGGYSGAFTTSSGMPYNNNMGNNNMNMNNNNLNATNNSQMPYGHASQVSTPTHSPYASSPSSSAHPNSGKSQSSLPLRRYILLPPPRKRKLHKTSDLGFPGVFPQKPGQDEDQMTHSNVKTGYIDKGIIQNETVSAQGILADRLQDPKKQHDLGAFMVQVLKKRQESSKIAGPSTFRPPNRATLNDQKKEQWLSDLSGTTPLRRLSKSVPHGFKAEKLLEALAQRQVPMLRATWYIKIVALSEMQAQRNRPSISQSQYSTEWTAIVSMFLKKQLLEINPHSPSKPAPTALNASSGSQNFKPWTSEEAKERWEAKWRYSVMLTKWQYNEGLLDHRHFLRATVEQLSSLCFEQIALLLSLIAMFLSEYARSRLLMRLLIEGLLNALQQLQRHPTYNQKLFRYSYLELELKRMLQSIFLSTPDMFVIPKAWTTHATLLQQVLLEDIQSSPHKPTSFPNVGSVLESHYNMIQARVRVFTHLNSTGTEPKIKGSRIGGNVEILDKVGPFSDLDEVAHEYFADFMDEDNGSSLPPSPSKSVFSPRSSSPFATPAGTSAASAFHHQDLAWKARVNTLCEWAITNSRYGHHRIFLVGTLLRLWRDSPNLAVHLSPLEKASRLQSALLEFLDSFNGTHHPLSQSDNSSHGHHQQQQHLDHHEQHLQHSSEDVLEAMARLFGNLIRDRLFSYQQYIQRLIARGDLQPNKRSQESTLRHLKYLQSFPLHQDAEAHHFNQRRVVLFGVDGEDDYDRECFETITAQIKTRLPYMFSTEAANMTVPIKDTPQDNQDLATPLPVQLTELIISASRFCQIRVTSQWLLEAVRLYVVKQIPIGEDNWRVMTSPGSSLLNGRQFATIVNVMEVASDFHSLYEMCIWLMEHTSDKTLLTYTVNLARKHYMVWAAMGVLTQFSQTILAKHYNLQGKNVLFKALPRFLALEAHNVPEDIRIELEGDLASLKTSIPAGATIPPQIQELQYVLKDPSPSAVSITASALHAKYGGLAHWPLRLFDGCIEALRKLDSTTRSQPDHSLNGFSSSAAAQEIVRASRIYAELLVEMAERVGNGCMDDVVHSWLRLHDIDWMTRVIGAEGHAEGTGASQPPIWFLSFMIQLVIQGFCSIDVLVQHMCADMLTKITDAVYPHGEDSHHQLHMEDVQLHQQPNASTLRLCSAIVHLLRLLLLEDASWNPRAHHAYGASHHVLSADHHPHRLGIQLTLAEIHALQTQRFSRLMTMQHTVRQGENRQNEDMQEAQDPSESEGYTSLQEQQMMLVQFQISRSLVWIESCLPLNHTVLHEIQEYRKDWALSADWLREKCLANVEGAYKIFLQTRQDQQSSIAGPESGFVKESANGSLQRHQEVVERKMMETFQMLVAESHESLLLLDTYGETSLTPSMIHQRTFRSIFLRVDRWIFDRCKVEFWLLLDTVMMERTGREKRSEGSGHSKDGVSAASRVSPSVTEGMMMMEGVTMTSGPGSSPLGDGTAGGSSGDSLQQLIHIFFQEFVLSERADKELLGRMLIGMRHDVVEEFIQYGYGLLAGHPSASFPQNVMIVQRPVESADYIRIVSNFHYVMEVLMGEGQPTVTLSLGGDEPSSQQAANAATPSASTPSATGFQPAATLTNSKRGSDCLQGLDATQLENRIGFAKNLLWQLKRFEERIKVFDVMHAIGCTFDEAAKVVQDNESGHGDMEDLLLTASLQKSDPQLVNSIQRQQRQRQQQQATASSIHLIDLRTSLSLRLRLLVPLLPVILQHPTSSACDLSTYLIRLTNLLVSSIVHGHGSEERLFEFCLDMVSCLMDEVLLLSGSLRGGVDELKSMRNDILNQLRTGLPQMTTSIPTVFASRIFRILPFQQHNVYFTSLRIGGDSGANTVGVGGIKAQHKEIQPRPWDWLEDCVGDVDQGQGQGSHAQQGQQSAQSPALGLALADSGSFSGLGNGDSTGGSGLLSGSASSFHGGSSSSLTGGGGGCHGGENLNDTSISLTLFGAKQVRKSTEGTTYQMQFQSGHGGGDDEQELLMVEEQQRPCEYNHSHQQQIWMLQHQRHQQQQQQLLLQQQQQEQLQQQLQQQQQLQRQQQQSQANADTPNVNGSSGVGGVGGVPMLGSRSSSSSGGIRSGSIPPLVRQQEPDPEQEEGQILGDDDLDMGWDITAPSLTPTLPATSIAIPATSGASMSPSILTGGGVSLMEDGELIEKMEDSEPLDMGQGASGAIASSIPVSITLPFVPVATAAPAAAVPAAKPPVPSKKKSSGNSKAARAAAATATATAAAAAAANANANANAAAAAAAAIANAPPVPTTTTAPAPTTTTKSRTGKGSRKGSKTQAAAATTAATVATEPMSVTSTSITVAPITSMAPGPSLQTTVGLPNAVTVTASLPPVQQQQQQQQQPMQFMPQGQAGQFQQAQPFGQLPLGFQGQQMRSVGGAGGGMQVPMSIALPGQPQQSGQMNSHQLMNAMRQGPNAMAMAMGMAGGTNAMSTGTTIGGIHVPMLSHQQLQQQPGQQQQQQPQYMDPSAFLATSGAAGNQVFGAGNPMNINLAHLGQPGGGGAGGGPRGANQHGGGGGQGGGFF
Length2621
PositionKinase
OrganismMortierella elongata AG-77
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mortierellomycotina> Mortierellomycetes> Mortierellales> Mortierellaceae> Linnemannia.
Aromaticity0.06
Grand average of hydropathy-0.384
Instability index50.95
Isoelectric point6.44
Molecular weight286157.46
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08835
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     104.01|      18|      18|    2432|    2449|       1
---------------------------------------------------------------------------
 2094- 2111 (30.15/11.52)	LQHQRH.QQQQQQLLLQQQ
 2112- 2127 (23.33/ 7.08)	QQEQLQ.QQLQQQQQLQ..
 2432- 2445 (26.86/ 9.37)	....QQ.QQQQQQQPMQFM
 2446- 2462 (23.66/ 7.29)	PQGQ..aGQFQQAQPFGQL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.95|      18|      18|    2311|    2328|       2
---------------------------------------------------------------------------
 2311- 2328 (31.45/20.21)	AAAATATA.............TAAAAAAANA
 2332- 2345 (23.72/13.17)	ANA....A.............AAAAAAIANA
 2354- 2384 (21.78/11.41)	APAPTTTTksrtgkgsrkgskTQAAAATTAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.58|      12|      18|    2588|    2603|       3
---------------------------------------------------------------------------
 2588- 2603 (13.79/12.75)	NlAHlGqpGGGGAGGG
 2608- 2619 (27.79/ 9.02)	N.QH.G..GGGGQGGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     178.12|      36|      58|    2468|    2503|       4
---------------------------------------------------------------------------
   17-   60 (48.90/17.15)	QYPPG.SGPGQGQggQSGQiNNGLG.......qgppmpGRMGFNTGRVTGPP
 2482- 2509 (39.49/12.38)	QVPMSIALPGQPQ..QSGQ.MNSH...............QLMNAMR......
 2510- 2537 (42.03/13.67)	QGPNAMAMA...........MGMAG.............GTNAMSTGTTIGGI
 2538- 2585 (47.71/16.55)	HVPM.LSHQQLQQ..QPGQ.QQQQQpqymdpsaflatsGAAGNQVFGAGNPM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.15|      19|      19|    1986|    2004|       5
---------------------------------------------------------------------------
 1986- 2004 (34.12/15.08)	SFSGLGNGDSTGGSGLLSG
 2008- 2026 (40.04/19.12)	SFHGGSSSSLTGGGGGCHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.20|      52|      56|    2165|    2220|       6
---------------------------------------------------------------------------
 2165- 2220 (77.42/53.03)	SGGIRSGSI..PPLVRQQEpDPEQEEgQILGDDDLDMGWDiTAPSLTPTLPaTSIAIP
 2223- 2276 (85.79/42.92)	SGASMSPSIltGGGVSLME.DGELIE.KMEDSEPLDMGQG.ASGAIASSIP.VSITLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     201.76|      49|      59|     647|     702|       7
---------------------------------------------------------------------------
  647-  699 (79.87/53.99)	NSRYGHHRiflvGTLLRLWRDSPNLAVHLSP..LEKASRLQSALL.EFL......D.SFNG.TH
  707-  753 (63.10/37.65)	NSSHGHHQ.....QQQHLDHHEQHLQ.HSSEdvLEAMARLFGNLIrDRL......F.SYQ....
 1200- 1251 (58.79/32.69)	...YPH......GEDSHHQLHMEDVQLHQQP..NASTLRLCSAIV.HLLrlllleDaSWNPrAH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.11|      20|      23|      64|      86|       8
---------------------------------------------------------------------------
   67-   86 (38.66/27.66)	GNQGQGGYSGAF..TTSSGMPY
   91-  112 (34.45/14.77)	GNNNMNMNNNNLnaTNNSQMPY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.27|      28|      38|    1477|    1510|       9
---------------------------------------------------------------------------
 1477- 1510 (39.85/33.29)	EFWLLLDTVMMeRTGrekrsEGSGHSKDGVSAAS
 1518- 1545 (52.42/27.79)	EGMMMMEGVTM.TSG.....PGSSPLGDGTAGGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.77|      15|      15|    1650|    1664|      10
---------------------------------------------------------------------------
 1650- 1664 (25.87/14.62)	PSSQQAANAATPSAS
 1666- 1680 (26.90/15.57)	PSATGFQPAATLTNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     152.19|      50|      59|     427|     485|      11
---------------------------------------------------------------------------
  427-  483 (72.09/57.70)	SLIAMFLSEYA...RSRLLMRLLIEGllnaLQQLQRHPTYNQKLfrYSYLELELKrMLQS
  487-  539 (80.10/47.40)	STPDMFVIPKAwttHATLLQQVLLED....IQSSPHKPTSFPNV..GSVLESHYN.MIQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.66|      29|     164|     828|     862|      12
---------------------------------------------------------------------------
  828-  858 (43.40/45.21)	LPYMFSTEAANMTVpIKDTP..QDNQDLATPlP
  876-  906 (47.26/27.02)	VTSQWLLEAVRLYV.VKQIPigEDNWRVMTS.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.37|      29|      59|     151|     184|      15
---------------------------------------------------------------------------
  151-  184 (47.01/35.78)	IL...LPPPRKRklHktsDLGFPGVFPQKPGQDEDQM
  209-  240 (45.37/22.72)	ILadrLQDPKKQ..H...DLGAFMVQVLKKRQESSKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.62|      16|      59|     312|     332|      18
---------------------------------------------------------------------------
  290-  305 (29.51/12.07)	EALAQRQVPMLRATWY
  313-  328 (29.11/19.13)	EMQAQRNRPSISQSQY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.77|      14|      18|     971|     988|      19
---------------------------------------------------------------------------
  971-  988 (16.68/25.14)	QFSQTILAkhynLQGKNV
  991- 1004 (23.08/15.90)	KALPRFLA....LEAHNV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     151.11|      45|     426|     594|     641|      21
---------------------------------------------------------------------------
  594-  641 (77.55/50.85)	GSSLPPSPSKSVFSPRSSSPFATPAgtsAASAFH..HQDLA.WKARVNTLC
 1026- 1073 (73.56/40.97)	GATIPPQIQELQYVLKDPSPSAVSI...TASALHakYGGLAhWPLRLFDGC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     207.87|      69|     424|    1261|    1337|      22
---------------------------------------------------------------------------
 1261- 1337 (101.63/93.77)	LSADHHPHRLGIQLTLaeihALQTQRFS...RLMTMQHTVrqGeNRQNEDMQEAQDPSESEG.......YTSLQEQQMMLVQfQISR
 1690- 1768 (106.24/71.41)	LDATQLENRIGFAKNL....LWQLKRFEeriKVFDVMHAI..G.CTFDEAAKVVQDNESGHGdmedlllTASLQKSDPQLVN.SIQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.84|      16|      23|    1547|    1562|      30
---------------------------------------------------------------------------
 1547- 1562 (28.26/18.74)	GDSLQQLIHIFFQEFV
 1573- 1588 (28.58/19.05)	GRMLIGMRHDVVEEFI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.50|      22|      23|     242|     263|      31
---------------------------------------------------------------------------
  242-  263 (40.04/31.08)	GPSTFRPPNRATLNDQKKEQWL
  268-  289 (36.46/27.37)	GTTPLRRLSKSVPHGFKAEKLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08835 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAAAAAIANAPPVPTTTTAPAPTTTTKSRTGKGSRKGSKTQAAAATTAATVATEPMSVTSTSITVAPITSMAPGPSLQTTVGLPNAVTVTASLPPVQQQQQQQQQPMQFMPQGQAGQFQQAQPFGQLPLGFQGQQMRSVGGAGGGMQVPMSIALPGQPQQSGQMNSHQLMNAMRQGPNAMAMAMGMAGGTNAMSTGTTIGGIHVPMLSHQQLQQQPGQQQQQQPQYMDPSAFLA
2) MSKFPGHTNHPRGAFPQYPPGSGPGQGQGGQSGQINNGLGQGPPMPGRMGFNTGRVTGPPSMGYHSGNQGQGGYSGAFTTSSGMPYNNNMGNNNMNMNNNNLNATNNSQMPYGHASQVSTPTHSPYASSPSSSAHPNSGKSQSSLPLRRYILLPPPRKRKLHKTSDLGFPGVFPQKPGQDEDQMTHSNVKTGYIDKG
3) NGDSTGGSGLLSGSASSFHGGSSSSLTGGGGGCHGGENLNDT
4) TEGTTYQMQFQSGHGGGDDEQELLMVEEQQRPCEYNHSHQQQIWMLQHQRHQQQQQQLLLQQQQQEQLQQQLQQQQQLQRQQQQSQANADTPNVNGSSGVGGVGGVPMLGSRSSSSSGGIRSGSIPPLVRQQEPDPEQEEGQILGDDDLDMGWDITAPSLTPTLPATSIAIPATSGASMSPSILTG
5) VFGAGNPMNINLAHLGQPGGGGAGGGPRGANQHGGGGGQGGGFF
6) VTLSLGGDEPSSQQAANAATPSASTPSATGFQPAAT
2336
1
1992
2049
2578
1641
2569
197
2033
2234
2621
1676










Molecular Recognition Features






MoRF SequenceStartStop




1) EQEEG
2) LPLRRYILLPPPRKRKLHK
3) RAAAATATATAAAA
2185
145
2310
2189
163
2323