<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08821

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMETKVTSKTSSLKALLLRAWRERWTDLQWGINIKTILPRGVSGDVYNLADCILQQALVGPGPNQLVLSYLKHSLSSQLVSYAAVLQRISKYDAFHKPHCIVSLLEFLESIQVGITCRGKPEEDLLAAAVLSIVHWLLQCYLHTLTKTPQSNPLTPHPSELIDKPASILQQMLNSDFLCAMMYLAKYDDKDLYIEVVKKCQEIETLLKTSTQKSVVPIEDSLKKLCNLEIESLCPEKTKMESITHCLQPLFAVQVLLNPSTETTVFVNQLLMVQRLKSYTNARLYCEIIRACLMCLHNVTGTFKESQWGAFTFLKVPHILKELHVTNLNGDEKFEYSQDILDAFELLLQFTPLLDIMDTTCSCNYVECLLNELQRVNLVTEKQAKQIGARREGVTTTSSIPKVIVRAGQTLNGILRTLNADYAKIQEGLLSVLYQVLTGKSFELMLAVATVEGELKTFVTKLIKFNECSKQINEPVPDKTAATRAMLFDVSFLMLCSIVQTYGSDVVLEEGGDSFFEQWVRECMPERNKLKSPQRMLQSVDSARVDALLAQINSPDPDFKSSNLKWHVACQSAMGAVKELLCAWESGVLGAGDVKRALDGLRATACCLPVCAAAWLCAYMSITHQDALLKPMNMVQHFLTPLSGDEMQDNLKDRSSLMVQIIRKMQYDVHPPTQSKTKVLSMSHSIISRQPILEQLESVWQNINQRGWINIQATQSLESLLNTGGSLWFVTNIVKEVLKYRYQEELDQAVDLAFAIFHLDIENCTLDLINHIIPQYLYNSMQSDELVEPQSSILAKLCVYCIFSTLEYNNSNPYRGNSRKRVRRDLDTDDLDALGVSNKLLRLNETGENVPMFSSQSPQAQGSSNGQKSVVILRDPLMTALNNLFTIFAFLAGRDGEVSQQTHFILQFLRLMVQCGKDRTRIVLQGMSQTLVPCLLKALPELFTTDILLRLYDIQTMIGRKATARDLCMLRNINLKPTK
Length978
PositionTail
OrganismTrachymyrmex septentrionalis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Trachymyrmex.
Aromaticity0.07
Grand average of hydropathy-0.036
Instability index46.57
Isoelectric point6.55
Molecular weight110257.87
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08821
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     295.13|      81|     381|     134|     299|       1
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  211-  299 (134.62/205.21)	QKSVVPIEDSL.KKLCNLeiesLCpektKMESITH...CLQPLFAVQVLLNPS.....TETTVFVNQL..LMVQRLKSYTNARL..YCEIIRACLMCLHNVT
  615-  672 (84.59/28.55)	......................LC....AYMSITHqdaLLKPMNMVQHFLTPL.....SGDE.........MQDNLKD..RSSL..MVQIIRKMQYDVHPPT
  866-  934 (75.92/20.76)	QKSVVILRDPLmTALNNL.........................FTIFAFLAG.rdgevSQQTHFILQFlrLMVQCGKDRTRIVLqgMSQTLVPCL.......
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     330.04|      98|     277|     413|     547|       2
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  103-  199 (143.61/98.63)	LLEFLESIQVGItCRG...........KPEEDLLAAAVlsiVHWLLQCYLHTLTKTPQSNPLTPHPseLIDKPASILQQMLNSDF..LCAMMYLAKYD.....DKDLYIE.VVKKC
  413-  522 (140.42/133.68)	ILRTLNADYAKI.QEGLLSVlyQvlTGKSFELMLAVAT...VEGELKTFVTKLIKFNECSKQINEP..VPDKTAATRAMLFDVSFlmLCSIVQTYGSDvvleeGGDSFFEqWVREC
  691-  734 (46.00/14.77)	ILEQLESVWQNInQRGWINI..Q..ATQSLESLLNTG......GSL.WFVTNIVK.............................................................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.57|      33|     704|      63|     102|       4
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   63-  102 (49.14/39.95)	NQLVLSYLKHSL.SSQLV.SYAAVLQRISKYdafhkphCIVS
  769-  803 (52.44/27.89)	NHIIPQYLYNSMqSDELVePQSSILAKLCVY.......CIFS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.76|      30|     285|     531|     560|       5
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  531-  560 (52.51/41.03)	SPQRMLQSVDSARVDAL.....LAQINSPD...PDFKS
  817-  854 (40.26/29.45)	SRKRVRRDLDTDDLDALgvsnkLLRLNETGenvPMFSS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08821 with Med24 domain of Kingdom Metazoa
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