<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08816

Description Mediator of RNA polymerase II transcription subunit 26
SequenceMRDTPMQRICSELTEKLLKSLDKEYNVVDIRAVVDVISTLEKTTVTKEVLEITRLGKHINELRRRTRNEALAKRAKDLVRRWRDMVLPTVHSTPSQPTLALNGAKEMALRNLKPQSPALRELKPHSPLSLKDATPLRVLSPALSVHSDHSRSPNASSNNKQSITLTSNHRISSCSRNASPTLGTSNQNHVTEAVPRTHSSNKRLRKEESSKDQCQYYQSPHGTESTIEEVKKQRLNGENISGNLNSQVPSPTLKERISDCFAETSLETTNDESGPKKRGRKKGSKSAKRQSFLEDSVKEKLASISRNPKLKTTQELLADLQARGSNCSPIGSANALPSQSVAEPPSTEDVLRGSNNEQVFKHLRCSSQKNSQSFHRSGLPSSETSTGKTQKAARLRVAENCRESPSPESCQDRLREDDRISGTIETSTCRSPLQRDLTVEEILAKLPPLDPSSIDWGEDEERDDAECFPPPRDATAEDLERLHMQCIEGLNGNFQPRLSMSTACSDGDERSNARGGGNGVSSGLSNVDSVKSVHNNQTDNVEFREWHQMLARPSYQGEILNIMPYVIID
Length569
PositionUnknown
OrganismTrachymyrmex septentrionalis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Trachymyrmex.
Aromaticity0.03
Grand average of hydropathy-0.862
Instability index64.28
Isoelectric point8.61
Molecular weight63206.85
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08816
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.34|      16|      41|     377|     417|       1
---------------------------------------------------------------------------
  377-  417 ( 6.50/51.45)	SGlpSSETSTgktqkaarlrvaenCReSPspescqdrLRED
  421-  436 (32.84/16.97)	SG..TIETST..............CR.SP........LQRD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.89|      19|      24|     146|     164|       2
---------------------------------------------------------------------------
  146-  164 (34.93/15.26)	H..SDHSR..SPNASSNNKQSIT
  169-  191 (25.96/ 9.74)	HriSSCSRnaSPTLGTSNQNHVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.57|      18|      42|     254|     271|       3
---------------------------------------------------------------------------
  254-  271 (30.09/18.28)	KERISDCFAETSLETTND
  298-  315 (28.48/16.93)	KEKLASISRNPKLKTTQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.00|      20|      21|      99|     119|       4
---------------------------------------------------------------------------
  100-  119 (33.02/20.10)	ALNGAKEMALRNLKP...QSPAL
  121-  143 (27.99/11.46)	ELKPHSPLSLKDATPlrvLSPAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.42|      19|      30|     202|     220|       6
---------------------------------------------------------------------------
  202-  220 (34.29/22.33)	KRLRKEESSKDQCQYYQSP
  233-  251 (33.13/21.32)	QRLNGENISGNLNSQVPSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      59.93|      13|      16|     477|     489|       8
---------------------------------------------------------------------------
  458-  473 (16.94/ 8.26)	EDEERDDAE..CFpppRD
  477-  489 (24.33/14.95)	EDLERLHMQ..CI...EG
  493-  507 (18.66/ 9.81)	NFQPRLSMStaCS...DG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08816 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KNSQSFHRSGLPSSETSTGKTQKAARLRVAENCRESPSPESCQDRLREDDRISGTIETSTCRSPLQRDLTVEEILAKLPPLDPSSIDWGEDEERDDAECFPPPRDAT
2) RLSMSTACSDGDERSNARGGGNGVSSGLSNVDSVKSVHNNQT
3) TVHSTPSQPTLALNGAKEMALRNLKPQSPALRELKPHSPLSLKDATPLRVLSPALSVHSDHSRSPNASSNNKQSITLTSNHRISSCSRNASPTLGTSNQNHVTEAVPRTHSSNKRLRKEESSKDQCQYYQSPHGTESTIEEVKKQRLNGENISGNLNSQVPSPTLKERISDCFAETSLETTNDESGPKKRGRKKGSKSAKRQSFLEDSVKEKLASISRNPKLKTTQELLADLQARGSNCSPIGSANALPSQSVAEPPSTEDVLRGSNNEQVFKHLRCSS
369
497
89
475
538
367










Molecular Recognition Features






MoRF SequenceStartStop




NANANA