<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08800

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMSSETQITNILNDILKVEAIEEAFSCVLVHHPKKETDKVAAWHQELRTAMTGLTKEQQEAAVRQFLSMAAAMTNHRRLQLLLSLLENLVHSNFLPARLVCECILSCDKLQYQLEDFWVECFVLIKHILGGVDYKGVREIMKGCKEKAQTIPPRLDASVQPQLKALENVIEFIFDRNACLLPGYFIVNEIQKAYPDGKNWPHWKLAKLLSDFVESFRHTAQMVSIVGHSKMLPVVEHTGYADYLINPWLLDPTTLKFSLKGNLPYDPDLLKPQTELLRYVLEQPYSRDMVCSMLGLQKQHKQRCVVLEEQLVELVILAMERSENETLPAEGMDGTVANHWVWLHLSSQLIYFILFQFACFPSIVMAIHDKLAGRELRKGRDHLMWVLLQFISGSIQRNPLSNFLPVLKLYDLLYPEKEPLPVPDYTQALCTHQMAITCIWIHLLKKAQTEPGTNIHRPIPHTLKVHHEFLQHLVMPNASLCMGSDYRIALLCNAYSTNQEYFSRPMAALVDTILGTQKNQQQQPLQNLQNNAALANGPTTPLSMSILDSLTVHSKMSLIHSIVTHVIKLAQSKSNMALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSHAWGTLYTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQTQLHLCVESTALRLITGLGSAEVQPQLSRFLSEPKTLVSAESEELNRALVLTLARSMHVTGTGADSLSGTWCKELLNTIMQNTPHSWANHTLQCFPPVLSEFFQQNSVAKENKQQIKKAVEEEYRNWASMNNENDIIAHFSVPGTPPLFLCLLWKMILETDRISPIAYKILERIGARALSAHLRKFCDYLVFEFANSVGGQHVNKCVDTINDMIWKYNIVTIDRLVLCLALRTQEGNEAQVCFFIIQLLLLKAAEFRNRVQEFVKENSPEHWKQSNWHEKHLAFHRKFPEKFAPEGIMEQTSGGPSQYQNLPVYFGNVCLRFLPVFDIVVHRYLEIPPVIKSLEILLEHLGCLYKFHDRPVTYLYNTLHYYEKKLRDRPLLKRRLVSAVLGSLREIRAPGWALSEAYQMYMTRFNDDAVSWVPELDYYIRLVQRIVETMSGTAHFPATDWRFNEFPNPAAHALYVTCVELMALPVAPDAVANFLLDVVAKGYTVVPSDEIHLWINCVGLLLAALPECYWSALHKRLLETISSPGLVNWQYNNLTPFQMFNFNITHNSLLENKYSYMLALAHSVWHHAGVGQITTMPQFIKEKLQPVVSSEEQLIYACHLIGPTLARFNAERPHCVVELAVCLYEMLERVDHTQTTLNYMDSICDLLVSYSLMCLSKDFYVPFYIFLNNSDRYHIKYMFVGDMTKNEVECIIRRLRPALQMRLRFIAHINIDEIHTS
Length1382
PositionTail
OrganismTrachymyrmex cornetzi
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Trachymyrmex.
Aromaticity0.10
Grand average of hydropathy-0.034
Instability index46.71
Isoelectric point6.73
Molecular weight158593.43
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08800
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.73|      34|     148|     454|     495|       1
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  454-  495 (56.85/52.19)	IHRPIPHTLKVH...........HEFLQHLVMPNaslcmgsdYRIALLCNAYS
  603-  647 (54.88/33.31)	ISQLLPTVFKSHawgtlytllemFSYRMHHIQPH........YRVQLLSHLHS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     496.60|     174|     260|     799|    1016|       2
---------------------------------------------------------------------------
  799- 1016 (262.52/315.56)	PGTPplfLCLLWKMIL...ETDRIS..P.IAY..KILERIgARALS..AHLrKFCDYLVFEFANSVGGQHVNKCVDTIN.............DMIWK.YNIVTIDRLVL...ClalrtqegneaqvcffiIQLLLLKAAE.....FRNRVQEFVkeNSPehwKQSNWHEKHLAFHRKFPEKFAPEGIME.QTS............GGPSQyqnlpvyfgnvcLRFLPVFdivVHRYLEipPVIKSLEILLE..HL.G.CLYKFH.DRP
 1055- 1278 (234.08/178.40)	PGWA...LSEAYQMYMtrfNDDAVSwvPeLDYyiRLVQRI.VETMSgtAHF.PATDWRFNEFPNPAAHALYVTCVELMAlpvapdavanfllDVVAKgYTVVPSDEIHLwinC.................VGLLLAALPEcywsaLHKRLLETI..SSP...GLVNWQYNNLTPFQMFNFNITHNSLLEnKYSymlalahsvwhhAGVGQ............ITTMPQF...IKEKLQ..PVVSSEEQLIYacHLiGpTLARFNaERP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     209.10|      65|     262|       8|     132|       4
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   55-  120 (111.15/127.16)	KEQQEAAVrQFLSMAAAMTNHRRLQLLLSLLENL.VHSNF.LPARLVCECI.LSCDKLQYQLEDFWVEC
  517-  584 (97.95/41.30)	KNQQQQPL.QNLQNNAALANGPTTPLSMSILDSLtVHSKMsLIHSIVTHVIkLAQSKSNMALAPALVET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     215.89|      68|     580|     126|     215|       5
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  139-  209 (112.26/111.81)	IMKGCKEKAQTIPPR.LDASVQPQ...LKALENVIEFIFDRNAClLPGyfIVNEIQ.....KAYPDGKNWPHWKLAKLLS
  315-  391 (103.63/56.11)	ILAMERSENETLPAEgMDGTVANHwvwLHLSSQLIYFILFQFAC.FPS..IVMAIHdklagRELRKGRDHLMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.50|      24|     272|     392|     417|      13
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  392-  417 (38.83/31.54)	GSIQRNP.LSNFLPVLKlyDLLYPEKE
  675-  699 (36.67/22.42)	GSAEVQPqLSRFLSEPK..TLVSAESE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08800 with Med23 domain of Kingdom Metazoa
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