<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08797

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMVTGPTEHGIQADVIFVIEGTAVNGAYLNDLKTNYVIPTLEYFSQGGIEDREYVAENSTTLYGIVVYHAADCLPSPCTETLGPYSNPHKLLMVLDKLEMVGGKGESFANIGEGLATGLLCFEDLQLRREPNTASQKHCILICNSPPYQTMIQETYKFAGHTIEQLATIYQERNINISILSPRKIPALYKLFEKAGGDLQSSQTKNYAKDPRHLVLLRNYNLKERPVSPQMGGNVHNTAATAAQIPLSPLQSNDSPNTNQVQQNIAPPNQQQGPPFRNQAPPQNITSVHQTVTPSMAAPMNTARPPYNPQIAAPPNYHPPGVNIATRPRWMRPFIAPGATAPANTQGSALIAQLTQPPSSLGLNVAAFNQRLDVAGNNVMAANQQQQQQQLTQQQQQLRLTMQLQQQNVQQATMSMAAQPTHNQPGSQLTASCISQSVPTQVSQTVTASQQAPVSVSSITQQITHSQAQGNVSTGTVQNQQLVPRERQNIWQGIVEWIEKAKNPTDAQKQTRHVPCQVSANAKDGDPELKADTWPPKLIMQLMPKQLIGSIGGTYLKNSKSVVFHPTPCEALESLTKMMTAGFAGCVHFTSASSSPACEIKVLILLYTTDKKTYLGFIPNDQTAFVDRLRKVIQQQKTSQNASVRQANPGPGNTIPAPMPTTGTQGGILMSQTNTMAMGGGQITQNIVSTVPPQTLTSTSGPQMTQMNMQNSGISGPQANTGAGGMIGQQRPPYDDIEIARHQNLLKIQHLRQTLEAAQQQEAQYKSQLEVNIQQNLEVAQQQEMQYKQQLEAQQAQRGLNPAAMANQQANSQRLMRPVSTNNLGLRHLLQQPQPQYSVRQVFGVQQQMVGPRGQIATRPMAPGNAQNQQFEDVSNYDFLG
Length880
PositionUnknown
OrganismTrachymyrmex cornetzi
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Trachymyrmex.
Aromaticity0.05
Grand average of hydropathy-0.511
Instability index53.05
Isoelectric point8.80
Molecular weight96142.55
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08797
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     188.75|      34|      35|     279|     312|       1
---------------------------------------------------------------------------
  280-  312 (52.35/16.68)	..PPQ.NITS....VHQTVTPSM...........AAPMNTARPPYNPQIAA
  317-  348 (30.40/ 6.60)	H.PPGvNIATrprwMRPFIAPGA...........TAPANT.......QGSA
  404-  430 (37.45/ 9.84)	..QQQ.NV........QQATMSM...........AAQPTHNQP..GSQLTA
  662-  704 (33.16/ 7.87)	G.TQG.GIL.....MSQTNTMAMgggqitqnivsTVPPQTLTSTSGPQM.T
  705-  738 (35.39/ 8.89)	QmNMQ.NSGI....SGPQANTGA...........GGMIGQQRPPY.DDIEI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     127.73|      27|      29|     181|     207|       2
---------------------------------------------------------------------------
  146-  173 (20.79/ 7.26)	PYQtmIQET..YKF...AGHTIEQlatiYQERN..
  181-  207 (46.71/25.33)	PRK..IPAL..YKLFEKAGGDLQS....SQTKNYA
  210-  238 (38.46/19.58)	PRH..LVLLrnYNLKERPVSPQMG....GNVHNTA
  241-  256 (21.77/ 7.94)	AAQ..IP.L..........SPLQS....NDSPN..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     120.99|      20|      20|     750|     769|       3
---------------------------------------------------------------------------
  374-  391 (28.15/10.94)	AGNNVMAANQQQQQ..QQ.LT
  750-  769 (34.14/15.19)	LRQTLEAAQQQEAQYKSQ.LE
  772-  791 (34.95/15.77)	IQQNLEVAQQQEMQYKQQ.LE
  795-  815 (23.75/ 7.82)	AQRGLNPAAMANQQANSQrLM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.74|      18|      29|     524|     552|       4
---------------------------------------------------------------------------
   87-  104 (32.38/10.45)	PHKLLMVLDKLEMVGGKG
  534-  551 (33.35/13.02)	PPKLIMQLMPKQLIGSIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.19|      16|      16|     446|     461|       7
---------------------------------------------------------------------------
  446-  461 (27.63/14.98)	TASQ.QAPVSVSSITQQ
  463-  479 (23.55/11.65)	THSQaQGNVSTGTVQNQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08797 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKNPTDAQKQTRHVPCQVSANAKDGDPELKA
2) GQITQNIVSTVPPQTLTSTSGPQMTQMNMQNSGISGPQANTGAGGMIGQQRPPYDDIEIARHQ
3) QQEMQYKQQLEAQQAQRGLNPAAMANQQANSQRLMRPVSTNNLGLRHLLQ
4) QQKTSQNASVRQANPGPGNTIPAPMPTTGTQGGILMSQTNT
5) RPVSPQMGGNVHNTAATAAQIPLSPLQSNDSPNTNQVQQNIAPPNQQQGPPFRNQAPPQNITSVHQTVTPSMAAPMNTARPPYNPQIAAPPNYHPPGVNIATRPRWMRPFIAPGATAPANTQGSALIAQLTQ
6) VAGNNVMAANQQQQQQQLTQQQQQLRLTMQLQQ
7) VSVSSITQQITHSQAQGNVSTGTVQNQQLV
500
680
781
634
224
373
453
530
742
830
674
355
405
482










Molecular Recognition Features






MoRF SequenceStartStop




NANANA