<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08776

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMVEKMSSETQITNILNDILKVEAIEEAFSCVVVHHSKKETDKVAAWHQELRTVMTGLTKEQQEAAIRQFLSMAAAMTNHRRLQLLLTLLENLVQSNFLPARLVCECILSCDKLQYHLEDFWVECFVLIKHILGGVDYKGVREIMKGCKEKAQAIPARLDASVQPQLKALENVIEYIFDRNACLLPGYFIVNEIQKAYPDGKNWPHWKLAKLLSDFVESFRHTAQMVSIVGHSKMLPVVEHTGYADYLINPWLLDPTTLKFSLKGNLPYDPDLLKPQTELLRYVLEQPYSRDMVCSMLGLQKQHKQRCIVLEEQLVELVILAMERSENETLPAEGMDGTVANHWVWLHLSSQLIYFILFQFACFPSIVMAIHDKLAGRELRKGRDHLMWVLLQFISGSIQRNPLSNFLPVLKLYDLLYPEKEPLPVPDYTQALCTHQMAITCIWIHLLKKAQTEPCTNIHRPIPHTLKVHHEFLQHLVMPNASLCMGSDYRIALLCNAYSTNQEYFSRPMAALVDTILGTQKNQQQQPLQNLQNNAALANGPTTPLSMSILDSLTVHSKMSLIHSIVTHVIKLAQSKSNMALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSHAWGTLYTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQTQLHLCVESTALRLITGLGSAEVQPQLSRFLSEPKTLVSAESEELNRALVLTLARSMHVTGTGADSLSGTWCKELLNTIMQNTPHSWANHTLQCFPPVLSEFFQQNSVAKENKQQIKKAVEEEYRNWASMNNENDIIAHFSVPGTPPLFLCLLWKMILETDRISPIAYKILERIGARALSAHLRKFCDYLVFEFANSVGGQHVNKCVDTINDMIWKYNIVTIDRLVLCLALRTQEGNEAQVCFFIIQLLLLKAAEFRNRVQEFVKENSPEHWKQSNWHEKHLAFHRKFPEKFAPEGIMEQTSGGPSQYQNLPVYFGNVCLRFLPVFDIVVHRYLEIPPVIKSLEILLEHLGCLYKFHDRPVTYLYNTLHYYEKKLRDRPLLKRRLVSAVLGSLREIRASGWALSEAYQMYLTRFNDDAVSWVPELDYYIRLVQRIVETMSGTANFPATDWRFNEFPNPAAHALYVTCVELMALPVAPDAVANFLLDVVAKGYTIVPSDEIHLWINCVGLLLAALPECYWSALHKRLLETISSPGLINWQYNNLTPFQMFNFNITHNSLLENKYSYMLALAHSVWHHAGVGQITTMPQFIKEKLQPVVSSEEQLIYACHLIGPTLARFNAERPHCVVELAVCLYEMLERVDHTQTTLNYMDSICDLLYHIKYMFVGDMTKNEVECIIRRLRPALQMRLRFIAHINIDEIHTS
Length1361
PositionTail
OrganismCyphomyrmex costatus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Cyphomyrmex.
Aromaticity0.09
Grand average of hydropathy-0.031
Instability index47.03
Isoelectric point6.72
Molecular weight156105.64
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08776
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     225.90|      72|     260|      24|     136|       1
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   52-  125 (117.74/133.08)	TVMtGLTKEQQEAAIrQFLSMAAAMTNHRRLQLLLTLLENL.VQSNF.LPARLVCECI.LSCDKLQYHLEDFWVECF
  515-  589 (108.17/51.10)	TIL.GTQKNQQQQPL.QNLQNNAALANGPTTPLSMSILDSLtVHSKMsLIHSIVTHVIkLAQSKSNMALAPALVETY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     448.75|     115|     260|     906|    1020|       2
---------------------------------------------------------------------------
  906- 1020 (205.91/123.94)	IQLLLLK....AAE.....FRNRVQEFVK..ENSPEHWK.QSNWHEKHLAFHRKFPEKFAPEGIME.QTS............GGPSQYQNLPVYFGNVCLRFLPVFDIVVHRYLEIPPVIKSLEILLE..HL.G.CLYKFH.DRP
 1067- 1167 (134.71/78.48)	YQMYLTRfnddAVS.....WVPELDYYIRlvQRIVETMSgTANFPATDWRFN.EFPNP.AAHALYV.TC................VELMALPVAPDAVA.NFL..LDVVAKGYTIVP....SDEIHL...WI.N.CV........
 1169- 1282 (108.13/61.51)	..LLLAA....LPEcywsaLHKRLLETI....SSP...G.LINWQYNNLTPFQMFNFNITHNSLLEnKYSymlalahsvwhhAGVGQ............ITTMPQF...IKEKLQ..PVVSSEEQLIYacHLiGpTLARFNaERP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     252.90|      82|     278|     391|     480|       6
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  391-  480 (134.71/83.97)	LQFIS..GS..IQRNpLSNFLPVLKlyDLLYPEKEPLP...VPDYTQAlcthqMAITCIWIHLLKKAQTEPCTN.IHRPIP.....HTLKVHHEFLQHLVMPN
  672-  766 (118.19/57.43)	LRLITglGSaeVQPQ.LSRFLSEPK..TLVSAESEELNralVLTLARS.....MHVTGTGADSLSGTWCKELLNtIMQNTPhswanHTLQCFPPVLSEFFQQN
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08776 with Med23 domain of Kingdom Metazoa
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