Description | Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MMMPGKTPVQENPLGLSWHDSTWIPVLNPSNIMDYFSERSNPFYDRTCNNEIVKMQRLSPDQLNNMTGLEYILLHVQEPILYVIRKQLRHSPTQASAVADYYIIAGVVYQAPDLGSVVSSRLLSTVHHLQSAFDEASSCSRYHPSKGYSWDFKNGKALAAKKETPVREEPSSLFQRQRVDMLLAELTRKFPLPVPKPVHQATEASVEIKQEVKTEKKDMKPPPEKKPRLN |
Length | 230 |
Position | Head |
Organism | Cyphomyrmex costatus |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Cyphomyrmex. |
Aromaticity | 0.08 |
Grand average of hydropathy | -0.564 |
Instability index | 54.38 |
Isoelectric point | 8.94 |
Molecular weight | 26245.80 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 PIRNR:PIRNR023869 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP08769 No repeats found |
MoRF Sequence | Start | Stop |
1) ATEASVEIKQEVKTEKKDMKPPPEKKPRLN 2) ELTRKFPLPV | 201 185 | 230 194 |
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