<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08767

Description XK-related protein
SequenceMHNINRERNNVTWVALALQAVWRSSMLISRFIVLLLALIFLKAWFFLFLGDNRHFPGLHWFIMTIWVILQKTKFCSTAWEERIYNCVIGLIYCFDFFNLRDDRSRYRVLIFYSVIAAQNVIFLIIYMLHVGETIAMIMIASVIVSCMLIGLTSMSLYYGKFHPSRTATNISRNISEHSTTTKVDASRSFKLFHRDSLVSLHHSMDISPRTEEVPTDKQSLLTNIAQISDCVEEGIVNRNYSSENEFNASALRLSTECERSHSRIGVKHKEEVTLVNDNPDNALTSSAPLNSLYSGLPDIDSSRKRRGIYEHDITPQLDWHAPDILNIDLNQLGSLDNSERSNSLTLDSCSKVIGALDVIKNREKLTTPTPLESSRIFDIEKQRDETMSCVTSIHDYENVCPLGIARPPWCIRSWKGYTDIETYIHDDSVVRDRRRDTLTSTTGTTYSSEYSDGMISRGILKQDDYADALTYDLVESKGNKSSYSDSTFSTSDDQNASLYIAKPVVFDDRGGMLALDTILEERDDLSSSDEKFQHGSELSRDSASTLVSTIDQIRRYTAENSPRHIYHTTGTHWEDLNPKNLMAQARFAKVLFDNDLRNASTTTGSIDLTARDVEKREIDAIREFVRCCAIESIKKTPLIDAVLSDSPILDKASKLMRQVTFADCKNDFDTNESDLYVEMSPLVSVENGENLCQARPIDTKTAEADESDTLKRNTLPTISKKSPNKENLSPSLSNNNRRINNIYDDKDNNDSHAWTIERDEKNDKSLCNMRFNLKEKRHLFLEQVLSPVPKLWNKLGQPSPGGGSASDKGKEWQMEFLMEKLRSKSSTYKPLVETAKNMRMAMLDKRFAIDSIEKNQLQKCLDTLQHSIKVTSFQSMVERLESLARQLGLKFMMSGPPGTEIFISSDMFFLEVLLEPPSGLVRDVKIHHEGKSEQQSCEALASALSHGDFVDFTTQLEGLASIYQLNADKKVKCKAFSALQSLEADLGILAQLQTFMKEPFNLVHKSPVGILERRRGGHPMKLTYFVSPYDLIDEENRTYDALNSDTIIKRKIGHSVTVCMEGSTGHKLPTSSIITVNRSPTGKSTPSYAPLTSTNSSMLPACFVLKLVKKMPICMELVKRIQKVTELECGDISAPHPLLSLIIQHASDGQLDCRNNRGLYVTLPDQQHCYFMTENKNMEGVLVCSIPFTHPAHVPQILVYLRQQALFNCLVASCVRPMARQDPEHTTILEVSALSWQHISVSVEHPYEETMATAELDLTDISMLKCRLYGMSMTTNVEQTSDLSGRVLQRCLSIPLTMRMLLKIWEGRSLPAVMNSLTSGSGSSNGSYNLNLGSGANSTSTSMLNPLQLGALLGQAKNSLTSNSNTNERGKKTRKRKTGTDGLWRSPKRKSDGGDNNTATEILLESSSSENSTPLGTPTSRENLAETRTSTPTSATSLTSGMDFSNLDTTDILDKSASDYDLDNSEKDSEIMEVQHSSTEQQQQQQPQQEVEELIKMRESSSTRKSKKNRSSGGSEEKKSSPTNIFVDETSTTSNGNKGLPVPPSVSITPISCGNLDQASTTNYNSVLTGMGLERRPGIEIIPIASSPSQTNLPSSITITPIAGPTPSPKTGSLTSATEDRQRSERKSGGGKSSSSSSKSSSEDTKSGGSKLEKRRKRKREDGPMGPPDKVPSGGKQQQDPLSKPVSVSIKPSTEQSPPSGGSAGVGLSCSSSRPTSPAAVRKFSPSPTHSSSLATLVGKSSPTLKAGQSAAATCGKPVQSPKHSPVYGSTVSVPVPASASPKHGNTSSPKHGSSAASSGKPSMSALKSAANSPSSKSSSSSSSDSATTPSKVKSSSSSSSKDSSGRGDKDRRTSSVSSSGGSGSGHQSPKTKSSSSKMKLEMISPGSEATQVSSLQASGGSTPPSGQVDAASKSAIAAQQARNRKSSLNAVIDKLKNAQHCTETDACGNGGGNVKGSGSSGLSSTGGMSSAGQKEKNIGGSGSSSSSGGKTIGEGGKSCVTKNASIDTKNPGEYMVKHSSDGIKITINKTRTKDSKQAANLKLSSSGSMAATSSSSSLSSVASSSSSSSSSSNVITGNNGSPKTHTGLKPGVNSGPASKKPQTLQATQKMLPTKMMLAAAGMKSAISSSGATNTGTGAGITASATGGVGGNPLSKSSSSKASGSPKTSSGVTDLSRGRDKPRISKSGDKGIFASKGLGDARKSSPSALREESESERAFKLLAAHASISNLPPSLPPQLMMEGLMKQLDTKFQIPKLSARANVADADKNKSSDKLSILPDSTKQTLDGLKQEQSKIAGLSNITVSVSKSSQPDDQSRRDHSQNKPDNLSITTSAASAISLNLVGENTGLMLPPQSTADSDVPTNLCIQPMVDNEPSRDSCKDLGMRQTSTGQQFLGKIDDTNVGGILSKSNVSDQLTSSGAKSYGTMTSSNTSTASSGAIVAESLNLSTKPADQAVLQTKYNKITVEEKKQQQTSSASLSSSSSSSSSSSSSLIFSSLASVATSSDAAAEMLLDFSAANKDSMTKGSHGLPVSLTQHHLTTIPERAMTQAAPTVRRNTPPPPPPPPPLPAPFPPAASPSVSVHIVKSPAPSPRVIPPSPHSSASPCITDDELMDEALVGMGK
Length2622
PositionMiddle
OrganismAtta colombica
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Atta.
Aromaticity0.04
Grand average of hydropathy-0.503
Instability index55.11
Isoelectric point8.70
Molecular weight282024.33
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-UniRule
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08767
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|    1094.67|     188|     191|    1614|    1801|       2
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 1360- 1451 (62.96/17.93)	............................................................................................................................................................L......TSNSNT..............NERG.............................KKTRK..RKTGTD.............GLWRSPKRKSDGGDNNTA........TEIllE....SSSSENST...PLGT...............................PT...SrE.NLAETRTSTP...TSATSLTSGMDFSN.....LDTTD.............
 1452- 1563 (131.13/46.33)	......IL.D.KSASDY.DLDNSEK.DS..EIMEVQ...HSS............................................................................................................................TEQ..............QQQQQPQ.QEVEE.........likmRESSSTRKSKKN..RSSGGS.............E....EKKSSPTNIFVDE........TST..T....SNGNK......GLPV...............................PP...S.V.SITP..................ISCGN.....LDQA..........STTN
 1564- 1730 (239.15/91.33)	YNSVLTGM.GlERRP................GIEIIPIASSP.....SQTNLPSSITITPI.......AGPTP............................................S.................................pktgsL......TSATED..............RQRSERK.SGGGK.............SSSSSSKSSSED..TKSGGS.............KLEKRRKRKREDGPMGPP........DKV..P....SGGKQQQD...PLSK...............................PV...S.V.SIKPSTEQSP...PSGGSAGVGLSCSS.....SRPTSPAAVRKFSPSPTH
 1731- 1926 (208.48/78.55)	SSSLATLV.G.KSSPTL.KAGQSAA.AT..CGKPVQSPKHSPVYG..STVSVPVPASASPK.......HGNTSS.....PKH...........................GSSAASSGK.................................psmsaL......KSAANSpssksssssssdsaTTPSKVK...................SSSS...SSSKD..SSGRGD.............K.DRRTSSVSSSGGSGSG........HQS..PktksSSSKMKLEmisPGSE...............................AT...Q.VsSLQASGGSTP...PSG...QVDAASKS.....AIAAQQARNRK.......
 1927- 2168 (166.56/61.09)	.SSLNAVI.D.K....L.KNAQHCT.ETdaCGNGGGNVKGSGSSGlsSTGGM...SSAGQK.......EKNIGG.......S...........................GSSSSSGGKtigeggkscvtknasidtknpgeymvkhssdgikitinK......TRTKDS..............KQAANLKlSSSGSmaatssssslssvASSSSSSSSSSNviTGNNGS...............PKTHTGLKPGVNSGPA........SKK..P....QTLQATQK...MLPT...............................KMmlaA.A.GMKSAISSSG...ATNTGTGAGITASAtggvgGNPLSKSSSSKASGSPKT
 2169- 2394 (118.29/40.98)	SSGVTDLSrG.RDKPRIsKSGDKGIfAS..KGLG.DARKSSP........SALREESESERafkllaaHASISNlppslPPQlmmeglmkqldtkfqipklsaranvadADKNKSSDK......................................LsilpdsTKQTLD............glKQEQSKI.AGLSN.............ITVSVSKSSQPD..DQS.........................RRDHSQNKP........DN....................LSIttsaasaislnlvgentglmlppqstadsdvPT...N.L.CIQPMVDNEP...SRDSCKDLGM..........RQTSTG..QQF......
 2395- 2600 (168.11/61.73)	.......L.G.KIDDTN.VGG.............ILS.......K..SNVSDQLTSSGAKS.......YGTMTS.......S...........................NTSTASSGA..............ivaeslnlstkpadqavlqtkynkI......TVEEKK..............QQQTSSA.SLSSS.............SSSSSSSSSSLI..FSSLASvatssdaaaemllDFSAANKDSMTKGSHGLPvsltqhhlTTI..P....ERAMTQAA...PTVR...............................RN...T.P.PPPPPPPPLPapfPPAASPSVSVHIVK.....SPAPSP...RVIPPSP.H
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.86|      50|     501|     769|     844|       3
---------------------------------------------------------------------------
  781-  844 (74.12/79.97)	LEQVLSpVP.......KLWNKLGQPSPGGGSASDKGkewqmeflmeklrSKSSTYK.PLVETAKNMRMAMLD
 1288- 1345 (76.75/34.92)	LQRCLS.IPltmrmllKIWEGRSLPAVMNSLTSGSG.............SSNGSYNlNLGSGANSTSTSMLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     168.96|      56|     501|     615|     675|       4
---------------------------------------------------------------------------
  615-  675 (78.01/75.95)	KReIDAIREfVRCCAIESikKTPLIDAVL...SDSPiLDKASKLMRQVTFADCKN.DFDTNESDL
 1119- 1178 (90.95/64.70)	KR.IQKVTE.LECGDISA..PHPLLSLIIqhaSDGQ.LDCRNNRGLYVTLPDQQHcYFMTENKNM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.14|      42|     187|     167|     208|       5
---------------------------------------------------------------------------
  167-  208 (71.36/51.03)	ATNISRNISEHSTTTKVDASRSFKLF.HRD....SLVSLHHSMDISP
  355-  401 (63.78/44.61)	ALDVIKNREKLTTPTPLESSRIFDIEkQRDetmsCVTSIHDYENVCP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.09|      23|     801|     275|     297|      12
---------------------------------------------------------------------------
  275-  297 (43.01/22.73)	VNDNPDNALTSS.APLNSLYSG.LP
 1076- 1100 (34.08/16.22)	VNRSPTGKSTPSyAPLTSTNSSmLP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08767 with Med1 domain of Kingdom Metazoa
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