<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08756

Description Cell division protein kinase 8
SequenceMMDYEFKMKTQKDRTKVEDLFEFEGCKVGRGTYGHVYKAHSELKSRPDTKDFGLKQIEGTGLSMSACREIALLRELKHVNVITLIRVFLSHNDRKVWLLFDFAEHDLWHIIKFHRAAKANKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPLEKDWEDIKKMPEHPTLLRDFKRSNYANCSLTKYMDRHKIKPDSKAFNLLQKLLMMDPNKRITSEHSMQDAYFQEEPLPTQDIFAGCPIPYPKREFLTDDDTEEKTENKARQNQQQTQQQTQQQQGNGDHNHGQNAKRVRLNGPHGAPEFHQHQSHAMTHQQPGMVYSTAQPTQPSNFHQRF
Length447
PositionKinase
OrganismAtta colombica
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Atta.
Aromaticity0.09
Grand average of hydropathy-0.686
Instability index40.80
Isoelectric point8.78
Molecular weight52062.96
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process
cell division	GO:0051301	IEA:UniProtKB-KW

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP08756
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.62|      13|      35|     379|     391|       1
---------------------------------------------------------------------------
  379-  391 (24.28/13.84)	QQQTQQQTQQQQG
  417-  429 (26.34/15.54)	QHQSHAMTHQQPG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP08756 with CDK8 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) IPYPKREFLTDDDTEEKTENKARQNQQQTQQQTQQQQGNGDHNHGQNAKRVRLNGPHGAPEFHQHQSHAMTHQQPGMVYSTAQPTQPSNFHQRF
354
447

Molecular Recognition Features

MoRF SequenceStartStop
1) AKRVRLN
401
407