<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08750

Description Mediator of RNA polymerase II transcription subunit 26
SequenceMRDTPMQRICSELTEKLLKSLDKEYNVVDIRAVVDVISTLEKTTVTKEVLEITRLGKHINELRRKTSNEALAKRAKDLVRRWRDMVLPTVHSTPSQPTLALNGAKEMALRNLKPQSPALRELKPHSPLSLKDATPLRVLSPALSVHSDHSRSPNASNNKQSITLTSNHRISSCSRNASPVLGTSNQNHVTEAVPRTHSSNKRLRKEESSKDQCQYYQSPHGTESTIEEVKKQRLNGENISGNLNSQVPSPTLKERISDCFAETSLETTNDESGPKKRGRKKGSKSAKRQSFLEDSVKEKLASISRNPKLKTTQELLADLQARGSNCSPIGSANALPSQSVAEPPSTEDVLRGSNNEQVFKHLRCSSQKNSQSLHRSGLPSSETSTGKTQKAARLRAAENCRESPSPESCHDRLREDDRISETIETSTCRSPLQRDLTVEEILAKLPPLDPSSIDWGEDEERDDAECFPPPRDATAEDLERLHMQCIEGLNGNFQPRLSMATACSDGDERSNARDGGNGVSSGLSNVDSVKSVHNNQTDNVEFREWHQMLARPSYQGEILNIMPYVIID
Length568
PositionUnknown
OrganismAtta colombica
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Atta.
Aromaticity0.02
Grand average of hydropathy-0.855
Instability index63.39
Isoelectric point8.17
Molecular weight63081.72
Publications









Function






Annotated function


ECO:0000256	RuleBase:RU364145

GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats
>MDP08750
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     477.35|     122|     128|      58|     183|       1
---------------------------------------------------------------------------
   58-  179 (204.04/109.53)	HINEL..RRKTSNEALAKR..AKDLVRRWRDMV.LPTVHSTPSQ.....PTL..ALNGA.KEMALRNLKPQ..SPALRELKPHSPLSLKD...ATPLRVLSPALSVHSDHSR...SPNASNNKQSITLTS.NHRIS...SCSRNASP
  188-  307 (138.16/74.66)	HVTEAvpRTHSSNKRLRKEesSKDQCQYYQS....P..HGTEST.ieevKKQ..RLNG...ENISGNLNSQvpSPTLKE.......RISDcfaETSLETTNDESGPKKRGRK...KGSKSAKRQSFLEDSvKEKLA...SISRN..P
  308-  431 (135.16/71.14)	.......KLKTTQELLA......DLQARGSNCSpIGSANALPSQsvaepPSTedVLRGSnNEQVFKHLRCS..SQKNSQSLHRSGLPSSE...TSTGKTQKAARLRAAENCRespSPESCHDR....LRE.DDRISetiETSTCRSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.52|      17|      21|     446|     466|       2
---------------------------------------------------------------------------
  446-  466 (27.62/29.13)	PPLDPSSidwgEDEERDDAEC
  469-  485 (32.90/20.63)	PPRDATA....EDLERLHMQC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08750 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RLSMATACSDGDERSNARDGGNGVSSGLSNVDSVKSVHNNQT
2) TVHSTPSQPTLALNGAKEMALRNLKPQSPALRELKPHSPLSLKDATPLRVLSPALSVHSDHSRSPNASNNKQSITLTSNHRISSCSRNASPVLGTSNQNHVTEAVPRTHSSNKRLRKEESSKDQCQYYQSPHGTESTIEEVKKQRLNGENISGNLNSQVPSPTLKERISDCFAETSLETTNDESGPKKRGRKKGSKSAKRQSFLEDSVKEKLASISRNPKLKTTQELLADLQARGSNCSPIGSANALPSQSVAEPPSTEDVLRGSNNEQVFKHLRCSSQKNSQSLHRSGLPSSETSTGKTQKAARLRAAENCRESPSPESCHDRLREDDRISETIETSTCRSPLQRDLTVEEILAKLPPLDPSSIDWGEDEERDDAECFPPPRDAT
496
89
537
474










Molecular Recognition Features






MoRF SequenceStartStop




NANANA