Description | Mediator of RNA polymerase II transcription subunit 11 (Fragment) |
Sequence | SPSNEAEPPSAYRPFTKAERIQQLNDIDKSITQLLQSAGLALKTLSASQSDSTQTPSARREAFENASNSYLKTLQKVDIGLKRQIYGLEESNIIPPEKAKRGRDGQDGSGMGGLRSAAAPAEPPSGESGMGRLDIGWLNSRSGRVGRDMEAELWDKAKVFLEDLERGNSN |
Length | 170 |
Position | Head |
Organism | Phialocephala scopiformis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Helotiales> Mollisiaceae> Phialocephala. |
Aromaticity | 0.05 |
Grand average of hydropathy | -0.806 |
Instability index | 59.69 |
Isoelectric point | 5.66 |
Molecular weight | 18434.22 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP08730 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 84.34| 24| 112| 1| 25| 1 --------------------------------------------------------------------------- 1- 25 (39.53/29.21) SPSNEAEPPSAYRPFTKAErIQQLN 116- 139 (44.81/28.43) SAAAPAEPPSGESGMGRLD.IGWLN --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) AEPPSAYRPFTKAERIQQL 2) EKAKRGR 3) LKRQIYGLEESNI 4) RDMEAELWDKAKVFLEDLER 5) SGMGRLDIGWLNSRSGRV | 6 97 81 147 128 | 24 103 93 166 145 |
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