<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08722
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MEEQQAAPALATAFPAPPPYWQSFTSENLDRLAELRAAQNPAKRTYDPSTELPLRILDLPAELRWLQPPVQPQEGKYKCFGDSYNLQDPLPSLVEMGIEQLYTPPDSPTISGVEKHTDRAFILKKLIKSLILNYLELVGVLSVNAEHYVEKTTDLNTLFTNFYHLLNEYRPHQARESLILMMQDQLDRCRAETQGIRDMKAKVEGILEGLGQAKLADIGEADTTSKEDSEGKEVWDELAREFN |
Length | 243 |
Position | Middle |
Organism | Phialocephala scopiformis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes>
Helotiales> Mollisiaceae> Phialocephala.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.523 |
Instability index | 51.08 |
Isoelectric point | 4.77 |
Molecular weight | 27574.87 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060
ECO:0000256 ARBA:ARBA00003669
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | negative regulation of transcription by RNA polymerase II GO:0000122 IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP08722
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 83.94| 26| 34| 46| 78| 1
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46- 72 (45.64/36.36) YDPSTEL..PLRIL.DLPAElRWLQPPVQP
80- 108 (38.30/15.25) FGDSYNLqdPLPSLvEMGIE.QLYTPPDSP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 36.50| 12| 30| 1| 12| 2
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1- 12 (21.15/13.00) MEEQQAA..PALAT
32- 45 (15.35/ 7.72) LAELRAAqnPAKRT
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