<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08681

Description Uncharacterized protein
SequenceMSRPPPPRRTAASPPAPAAPTPASPVPQLAPSGAPSNATRSTAIQTTPSVSHAFRQSPLDAILADQGLTRYHLEPPSWRAPWILEPHKDPSPSKHLGRAAGLLKVQSSAATAAAVAAAADKDDVDKGRTRPWPVFYPPRDGMDEDSMAEVLVKSGYSAKSVVQAETFSAHQHIYDKLKTTDVLGNLSRLVAAVHAKADESLPSYGPSTFRLPSRITLTDLKREAWFADLASPAVPLSKLSRSVPHGYKGEKGLDMLAHRRVEVPRAVWFVRAFGGIEIQSLAKTRPVSTAIGQYTAEFTTVVSEFVRKQLAEVVLPSSASSAAPACALTTTPGAPPSHPGTPTPVPVALAALGRSRSGSLGSAAQQQAQAVKAQAAADAARQGGAGGAAAGATTASAGAGGVSGGERGLGLFGDEDRRKTWEGKFDYTVRLVESLYQEALLDRPHFLYFLVSLLDPPSSTLPPPSTAPSEAGATLGQLSFALLLVEEYFGDLLQSETATARLVRAGLLRLEELESAPASPLSATVSTTLTSLIRSAFLAHPDSFVSLLPSPIYPLSTSRTNSPSRAAPGTPSSGARLEKLLLSTGQEHSIDDADDGAVLTETVAADVAELRARRALAQPTDGAALSSSSGSDESLEVDDQALLAAIERLDEIEFPARMRDVHRALFVAPAVRPLAHVCGSSPAGSRAPMGSSTRSPAQDGHPSLPADDVSSSTPSTSVRPLTLEHALPLLFTWCTTTTRPLPAPHRRYAVSRLIALELERLDGEGDGGRSRRLTRSSSHNPVPSVEDAFVRWIDERFPSSSTGVGGVGAAAAAGAAGPPAAPVERRDVRALAEELLRAGVLSYGAYLQRLIARGETEPGPVAGPSADAPTESLHLWILRTAALPASGVGARRRVVASGGEAGVARTLRVDELEGVVRTELGRLVFSEAMLAGAECGTLLRAVRALREEGAHGAVARELLPEGLSARLDQVSGRIGLEVEQMAVIVAVYEACEDWWGLVQLLVVILKLSPPLPVVLHIIDVLEAQLDVATTLDSLAEVGTALFAAHESLKMCHTPPERRLLALLRRLGTAGYLSTTAKDTLEADIRNLASSLTASRAQTQALPSPLTELQSLLIDSSSAAISQLASTLWFRYHAHPSWSTIALDSVLRMAPQLPPSTATCPSPAAALLRALHDRLPTGLEPVLARWVGSMSAAQLCATFGGPDGPVRAALLNELVVEGTIGAVAMLRGAVLPLRRVLLGLLTPTAAGQLVGAGHVIAPTDPAAAQALHNTHTILSSVIFSAPEPAAAGASPPSPSSPTALATQQRLAARRASLGTRPALPAVAASLALLVVQQDVASVLGLPDLAESTGAFFLRLGTLPELQTLVVRDPAAFKDAMLDSETVGAIPRIELFRPKLLAGLLLLLKDGGAATPASLVSTEDWDLFLSGLTLWRLSTSKVEVESCLERLELDDTISSADKVDALHTLSTHFLERVCSGEGQSYLGEQVVKCYKGSASDELVSVAFSRIADAITALTATSPSLETVGVARTTLRCASRLLDTLLQSGTATSRTDSIDRLLKAVKTGFLADSIDHLDPNETQDFTLDLAHLVAVALRCTRKPTEKSTAELYRDCIVPLARHAAHFARDLGQLCELLTLLFDTCSHLLFALPDLQPSLRPPTLHMLLSPSTSVPRLAIELLPDSTFARLTRLFGQYAPASLVANPWELLDHTDPSSVASAAVVRRSSQHPPPQLVNIGPLDLAAFRARVVETIPAVTALDAVSTTSTASSAPPGQSAPERGAQTSFDFETPCTTLPVAARDHRRTLAVTRLLAQRMEQNTATAAAHAQAQAQAQAQAQAASNSAGRKRAATGADAVKPQGATPAPPASAAAAAAASTTTSAPAAAAAPASGRGAKRKTSSSTTAEVVVLDSDEEQAPSKAKKARAGASSGSGAATAAARKTTGGKTASKTVKRKR
Length1948
PositionKinase
OrganismRhodotorula graminis (strain WP1)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Microbotryomycetes> Sporidiobolales> Sporidiobolaceae> Rhodotorula.
Aromaticity0.04
Grand average of hydropathy-0.014
Instability index52.77
Isoelectric point6.77
Molecular weight203649.81
Publications
PubMed=26441909

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08681
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|    1985.17|     423|     434|     337|     769|       1
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    6-  279 (271.76/80.66)	...................................PPRRTAasPPAPAAPTPA.SPVPQLAPSG..........................................APSNATRSTAIQTTPS.VSHAFRQSPlDAILADQGLTRYH..L.....EPPSWRAPwilephKD.P.SPSKHL...............GRA......................................AGLLKVQSSAATAAAVAAaadkdDVDKGRTRpwPVFYPPRDGmdedsmAEVLVKSGYSAKSVVQAETFSAHQHIYDKLKT.....TDVLGNL.......SR.LVA..AVHAKADESLPSYGPSTFRLPsritLTDLKREAwfADLASPAVPLSKLSRSVP....HGYKGEKGLDML............................AHR.R.V.EVP..R..AVW.FVRA.FG.GI...EIQ........................................................................................................
  421-  830 (598.87/193.99)	WEGKFDYTVRLVESLYQEALLDRPHFLYFLVSLLDPPSSTL..PPPSTAPSEAGATLGQLSFALLLVEEYFGD.LLQSETATARLVRAG........LLRLEELESAPASPLSATVSTTLTSLIRSAFLAHP.DSFVSLLPSPIYP..LSTSRTNSPSRAAP......GT.P.SSGARLEKL........LLSTGQE......................................HSIDDADDGAVLTETVAA.....DVAELRAR..RALAQPTDG......AALSSSSGSDESLEVDDQALLAAIERLDEIEF.....PARMRDV.......HRALFV..APAVRPLAHVCGSSPAGSRAP....MGSSTRSP..AQDGHPSLPADDVSSSTPSTSVRPLTLEHALPLLFTWCTTTTR..............PLPA.PHR.R.Y.AVS..RLIALE.LERL.DGEGD...GGR.....srrltrssSHN....P..V.PSVEDA.FVRwidERfpSSST...gVGGVGAAAAA....gAAGPPAA..........PVE..R.RDVR.A.........
  831- 1215 (363.97/112.25)	..........LAEELLRAGVLSYGAYLQRLIA....RGETE..PGPVAGPSADAPT...ESLHLWILRT..AA.LPASGVGARRRVVASggeagvarTLRVDELEG........VVRTELGRLVFSEAMLAG.AECGTLL.RAVRA..LREEGAHGAVAREL......LP.E.GLSARLDQV........SGRIGLEveqmavivavyeacedwwglvqllvvilklspplpvvlHIID......VLEAQL.......DVA............................TTLD.SLAEVGTALFAAHESLKMCHT.....P......................PERRLLALLRRLGTAG...Y....LSTTAKDT..LEADIRNL.ASSLTASRAQTQALPSPLTELQSLLIDSSSAAIS..............QLAS.TLWfR.YhAHPswSTIALDsVLRM.APQLP...PSTatcpspaaallraLHDRLPTG..LePV.LARwVGS...MS..AAQL...............................CATFGGPDGPV.RA.A.LLNELVV...
 1216- 1543 (349.36/107.46)	.EGTIGAVAMLRGAVLP...LRR.....VLLGLLTP...........................................TAAGQLVGAG........HV.IAPTDPAAAQALHNT.HTILSSVIFSA..PEP.AAAGASPPSPSSPtaLATQQRLAARRASL......GTrP.ALPAVAASL.......aLLVVQQ..............................................................DVASVLGL..PDLAEST...............G..........AFFLRLGTLPELQTlvvrdPAAFKD..........AMLD..SETVGAIPRIELFRP.....K....LLAGLLLL..LKDGGAATPASLVSTEDWDLFLSGLTL.........WRLSTSKvevesclerlelddTISS.ADK.V.D.ALH..TLSTHF.LERVcSGEGQsylGEQ..........vvkCYKGSASDelV.SVAFSR.I..........................ADAI......TALTATSPSLETVGVARTTlRCASrLLDTLLQSGT
 1544- 1891 (401.22/131.07)	ATSRTDSIDRLLKAV.......KTGFLADSIDHLDPNETQD..FTLDLAHLVAVALRCTRKPTEKSTAELYRDcIVPLARHAAHFAR.D........LGQLCELLTL....LFDTCSHLLFAL........P.DLQPSLRPPTLHM..LLSPSTSVPRLAIE......LL.PdSTFARLTRLfgqyapasLVANPWE.......................................LLDHTDPSSVASAAV.............VR..RSSQHP..............................................PPQLVNIgpldlaaFRARVVetIPAVTALDAVSTTSTASS.AP....PGQS..AP..ERGAQTSFDFE........................TPCTTL................PVAArDHR.RtL.AVT..RLLA....QRM.EQNTA...TAA.........ahaqAQAQAQAQ..A.QAASNS.AGR...KR......aatgADAVKPQGATPAPpaSAAAAAAASTTTSAPAAAAAPA..SGRG......AKRKT
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     203.58|      55|      57|     286|     340|       2
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  286-  340 (90.89/46.52)	PVSTAIGQYTAEFTTVVSEFVRKQLAEVVLPSSASSAAPACALTTTPGAPPSHPG
  344-  398 (81.81/40.98)	PVPVALAALGRSRSGSLGSAAQQQAQAVKAQAAADAARQGGAGGAAAGATTASAG
 1897- 1925 (30.87/ 9.87)	.........................AEVVVLDSDEEQAPSKAKKARAGA.SSGSG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08681 with Med12 domain of Kingdom Fungi
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