<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08666

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMDASKTTSKTSSLKALILKAWRERWTDIQWGINIKTILPRGVSGDLYNLADCILQQAMVGCGANQLVISYLKHSLASHLVSYAAVLQRIAKFDAFHKPHCILSLLEFLESFLDSVTCRGKMEEEILAYAVSSIILWLLQVYHYSLSKYPSSNPIQSQELLEKSTTLLNSIVNTDFLLAMFYLAKQNDPEEYDEVTKKCQEITAFMMMNTQFKAPLHIHETLQKICNMSIDKIAPLNIKSESLPHSLQALIAINVLATPSMDLQQLSSQLLMIQRIKGYSLSRLYCELIRACFISLNDSCKDSCRQAVWAAFTFLRVPQVIHYIHNTSGTSNKDAEHSMEVVEAFEKLLQSTPLLDIVDTKNCCNSVICLLEPLVKLNIVSETHLSYFKQKRETKDIKLQKLEPTALQGCVPSFITRAEPTLAGILKTMGGDFHKTQESLYAMLCQIVGGTTLDTILAVALVEGKLKLFVSRLIMFNEFALLAASEKGASPTKAYTFDISFLILCSIVQEHGVEAVLDDNGDSFFEQWVRDCMVHKGVHKSPEQILQKCDPQIVDIFLHHLSAPDFDFKNTNLKPHDLCLNVSGVVKEILFAWEQGSITPGDVKRMLDSLRQKMASLAVCASVWLCSYINVVHQDAFLKPINMVQLFLAPPTEIELSQIENFKERTILMGPIIRKMQYDVYPPSVPKTKVITFSHNIISRQPILEQLQTVWEDIKIRGHLQIDATHIIKSLLNTAGPVWFVTNLVKETLKYRYQEDLDRSVDVVLAMLHLDIERCTEALLLHVLPQYLYNAKLCEELVEPQSSILAKLSVYCIYAALEFSNCNKVPVSRKRRHDDTEDIDALCTANKVRRLNDNSSDSNSMYYSQQQIVAPGLMKEPLQSALEMVYKLFSQLAAKNGEVTPQTHFILQFLIYIVQCGQERAQIVLQKMPSEIVPTLIKALPDNFNIGLILRLYDLSTPHGRRDTARDLCLLRNMRLRPD
Length978
PositionTail
OrganismPapilio machaon (Old World swallowtail butterfly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Papilionoidea> Papilionidae> Papilioninae> Papilio.
Aromaticity0.08
Grand average of hydropathy0.019
Instability index51.16
Isoelectric point6.56
Molecular weight110774.75
Publications
PubMed=26354079

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08666
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     396.73|     113|     484|     129|     246|       1
---------------------------------------------------------------------------
  129-  243 (189.59/135.87)	AVSSIILWLLQVYHYSLS...KYPSSNPIQSQELLEKSTTLLNSIVNTDflLAMFY.....LAKQNDPEEYDEVTKKCQEITAFMMMNTQF..........KAPLHIHETLQKIC..NMSIDKIAP...LNIKSESLP
  279-  381 (147.33/93.64)	SLSRLYCELIRACFISLNdscKDSCRQAVWAAFTFLRVPQVIHYIHNTS............GTSNKDAEHSMEV......VEAFEKL.LQS..........TPLLDIVDT.KNCC..NSVICLLEPlvkLNIVSE...
  881-  957 (59.82/34.82)	...................................................LEMVYklfsqLAAKN.....GEVTPQTHFILQFLIYIVQCgqeraqivlqKMPSEIVPTLIKALpdNFNIGLI.....LRLYDLSTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     362.91|     116|     134|     385|     508|       2
---------------------------------------------------------------------------
  385-  508 (175.21/155.34)	SYFKQ.KRETKDIK.LQKLEPTALQGCVPSFItraePTLAGILKTMGGDFHKTQESLYAmLCQIVGGTTLDTILAV...ALVEGKLKLFVSRLimFNEFALLA..ASEKGASPTKAYTFDiSFLILCSIVQ
  522-  644 (187.70/138.71)	SFFEQwVRDCMVHKgVHKSPEQILQKCDPQIV....DIFLHHLSAPDFDFKNTNLKPHD.LCLNVSGVVKEILFAWeqgSITPGDVKRMLDSL..RQKMASLAvcASVWLCSYINVVHQD.AFLKPINMVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.27|      18|      46|      37|      54|       3
---------------------------------------------------------------------------
   37-   54 (32.01/17.30)	ILPRGVSGDLYNLADCIL
   85-  102 (33.27/18.23)	VLQRIAKFDAFHKPHCIL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08666 with Med24 domain of Kingdom Metazoa
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