<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08635

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMDASKTTSKTSSLKALILKAWRERWTDIQWGINIKTILPRGVSGDLYNLADCILQQAMVGCGANQLVISYLKHSLASHLVSYAAVLQRIAKFDAFHKPHCILSLLEFLESFLDSVTCRGKMEEEILAYAVSSIILWLLQVYHYSLSKYPSSNPIQSQELLEKSTTLLNTIVNTDFLLAMFYLAKQNDPEEYDEVTKKCQEITAFMMMNTQFKAPIHIHETLQKICNMSIDKIAPLNIKSDLLPHSLQALIAINVLATPSMDLQQLSSQLLMIQRIKGYSLSRLYCELIRACFISLNDSCKDSCRQAVWAAFTFLRVPQVIHYIHNTCGTSNKDAEHSMEVVEAFEKLLQSAPLLDIVDTKNCCNSVISLLEPMVKLNIVSESHLSYFKQKRETKDVKLQKLEPTGLQGCVPSFITRAEPTLAGILKTMGGDFHKTQESLYAMLCQIVGGTTLDTILAVAMVEGKLKLFVSRLIMFNEFALLAASEKGASPTKVYTFDISFLILCSIVQEHGVEAVLDDNGDSFFEQWVRDCMVHKGVHKSPEQILQKCDPQIVDIMLHHLSAPDFDFKNTNLKPHDLCLNVSGVVKEILFAWEQGSITPGDVKRMLDSLRQKMASLAVCASVWLCSYINVVHQDAFLKPINMVQLFLTPPTEVELSQIENFKERAILMGPIIRKMQYDVYPPSVPKTKVITFSHNIISRQPILEQLQTVWEDIKIRGHLQIDATHIIKSLLNTAGPVWFVTNLVKETLKYRYQEDLDRSADVVLAMLHLDIEKCTEALLLHVLPQYLYNTKLCEELVEPQSSILAKLSVYCIYAALEYSNYNKVPVSRKRRHEDTEDIDTLCTASKVRRLNDNSSDSSSMYYTQQQIATPGLLKEPLQSTLEMVYKLFSQLAAKNGEVTPQTHFILQFLIYIVQCGQERAQIVLQRMPSEIVPTLIKALPDNFNIGLILRLYDLSTPYGRRDTARDLCLLRNMRLRPD
Length978
PositionTail
OrganismPapilio xuthus (Asian swallowtail butterfly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Papilionoidea> Papilionidae> Papilioninae> Papilio.
Aromaticity0.08
Grand average of hydropathy0.008
Instability index49.22
Isoelectric point6.54
Molecular weight110884.87
Publications
PubMed=26354079

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08635
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     360.29|     115|     134|     385|     508|       1
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  385-  508 (173.70/137.73)	SYFKQkrETKDVKLQKleptGLQGCVPSFITRAEPTLAGIL..KTMGGDFHKTQESLYAM.LCQIVGGTTLDTILAV...AMVEGKLKLFVSRLimFNEFALLA..ASEKGASPTKVYTFDiSFLILCSIVQ
  522-  644 (186.59/121.68)	SFFEQ..WVRDCMVHK....GVHKSPEQILQKCDPQIVDIMlhHLSAPDFDFKNTNLKPHdLCLNVSGVVKEILFAWeqgSITPGDVKRMLDSL..RQKMASLAvcASVWLCSYINVVHQD.AFLKPINMVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.02|      46|     641|     198|     275|       2
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   34-   89 (57.45/21.16)	IKTILPRGVSGDLynLADCIlqQAMVgcGANQLVISYLK.HSLASHLVsyaaVLQRI
  229-  275 (72.58/19.34)	IDKIAPLNIKSDL..LPHSL..QALI..AINVLATPSMDlQQLSSQLL....MIQRI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     204.65|      64|     594|      99|     228|       3
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   99-  168 (92.43/169.30)	HCILSLLEFLeSFLDSvtCRGKMEEEILAyAVSsiILWLLQVYHYSLSKYPSSN..PIQSQELLEKSTTLLN
  284-  349 (112.22/55.05)	YCELIRACFI.SLNDS..CKDSCRQAVWA.AFT..FLRVPQVIHYIHNTCGTSNkdAEHSMEVVEAFEKLLQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.46|      27|      29|     649|     676|       4
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  649-  676 (42.50/30.65)	PPTeVELSQIENFKERAILMGPIIRKMQ
  681-  707 (46.96/29.45)	PPS.VPKTKVITFSHNIISRQPILEQLQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08635 with Med24 domain of Kingdom Metazoa
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