<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08624

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMADLQISNIVSDILRVEPVEEAFSSYLVYKPEQENEKLAMYQKKLCAMITSLSADLQESAIRQYLTHTAIQTNQYKMKQLLTILENLVNTNILQARMVCDCILSSDNLNYQNADYWIQSLNLIRRIIGGVDYKGVREIMKGCREKAHSLPMRLNSSTIPQMKALYNVLEYIFDRNASLLPAYFIVTEIQKDYPDNNHYPHWELANLFTSFIESFRPCAQMVSIIGHSSMLPVVEFSGYADHLINPWRLDPTTLKFSLKGNLPYDDELLKPQIALLRHVIQQPYSRDMMCSMLGLQKQHKQRCIALEDQLVELMISPMEKNEQENEEDEMSSTHWCWLHLSSQVIYLILIGFASFSNIVMGLHNKLTGHNLKKGRDHLMWVLLQFISGSIQRHPLSDFLPIIKLYELLYPEKEPLPVPDWTRAHSTHQMAVVCIWMHLLKKAETEHKTMSMPQNLKVQYEFLQHLMSSNNTPSLMGGDYRIPLLCNAYSTKQECYTRPMGIIIETLFGIQKPLPNGNPGTPLPTMPLSMCILDSLTLHCKMSVIHSIVTHVAKLAQNKTNLPGSSMMAPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHNLLDMFSYRIHHIQPHYRVTLLSHLHSLAACPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSEPKSLVSSDSEELNRVLVLTLARGIHMTGTGSDSAAVKELLTTIMANTPHNWSQHTLQCFPPVLVEFFSQNTAQKENKQLLKKYVEEEYRKWSSMANDNDIISHFSVPVAPLFVCLLWKIIFETNRINPIAFKILERIGARALSAHVRKFCDYLMYEVTNPAGGPHINKCVDAINDIVWKYNIVTIDRLVLCLVLRPNLDGNESQVCLYIIQLLLLKGSELRNRAQDFVKENSPEHWKQNNWYEKHLAFHRKYPEKFAPEEASGTYGGTIPVYLSNVCLRIIPVLDVVVHRHLEIPQVSKNLEQLLEHIGYLYKFHDRPITFLYNTLHYYELKLRDKPLLKRKLVNAVLGSLKDVRPAGWATTEAFQSYLARPEVDATSWTPDLNYYLSLVNRMVDTMTGQSHFPNTDWRFNEYPNPSAHALYVTCVELMSLPFPPNVVGNSLLEIITSGFVVIPTTKIQLWVNAVGLIMAALPDPYWNVIHDKILELITSNEIIEWPYSESPFQIFNLKTTNATMLENKYSLTLALGHAIWYHAGTGQIVQVPTFVKEKLSPEIRTETQLLFLCHMVGPLLQRFNSDISRVVMDITLTLYELLAHIDKLQPHLQYVDPICDLLYHIKYMFVGDIMKNEVENVIRKLRPALQMRLRFITHLNVDQINAA
Length1336
PositionTail
OrganismPapilio xuthus (Asian swallowtail butterfly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Papilionoidea> Papilionidae> Papilioninae> Papilio.
Aromaticity0.09
Grand average of hydropathy-0.079
Instability index43.41
Isoelectric point6.85
Molecular weight153287.33
Publications
PubMed=26354079

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08624
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     245.17|      85|     287|     919|    1035|       1
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  932- 1035 (113.89/158.84)	EKFAPEeasgTYGGTIPVYLsnvCLRIIPVL...DVVVHRhlEIPQVSKNLEQLLEHIGYL...YKFHDrPI.TFLYntlHYYELKLRDkpLLKRKLVNAVlgslKDVRPA
 1226- 1317 (131.27/87.72)	EKLSPE....IRTETQLLFL...CHMVGPLLqrfNSDISR..VVMDITLTLYELLAHIDKLqphLQYVD.PIcDLLY...HIKYMFVGD..IMKNEVENVI....RKLRPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.43|      17|     287|      30|      46|       2
---------------------------------------------------------------------------
   30-   46 (31.66/20.37)	KPEQENEKLAMYQKKLC
  319-  335 (33.77/22.22)	KNEQENEEDEMSSTHWC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.22|      21|     289|     591|     627|       8
---------------------------------------------------------------------------
  591-  611 (38.73/44.10)	FINQL.LPNVFKSHAWGILHNL
  642-  663 (30.49/ 7.16)	QANQTqLQLCFESTALRLITSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.19|      33|      39|    1094|    1126|      13
---------------------------------------------------------------------------
 1094- 1126 (61.09/41.57)	PSAH.ALYVTCVELM..SLPFPP.NVVGNSLLEIITS
 1132- 1168 (47.10/30.17)	PTTKiQLWVNAVGLImaALPDPYwNVIHDKILELITS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08624 with Med23 domain of Kingdom Metazoa
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