<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08611

Description Heat shock protein 70-3701
SequenceMSGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFSDPSVQSDMKHWPFKVVPGAGDKPMIVVNYKGEDKQFSAEEISSMVLIKMKEIAEAYLGITIKNAVVTVPAYFNDSQRQATKDAGVISGLNVMRIINEPTAAAIAYGLDKKASSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKSTAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDISGNARALRRLRTACERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCMDPVEKCLRDAKMDKSNVHDVVLVGGSTRIPKVQQLLQDFFNGKDLCKSINPDEAVAYGAAVQAAILSGEGNEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERTRTKDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKEEIEKMVQEAEKYKAEDEEHKKKVEAKNTLENYAYNMRNTIKDEKISSKLAADDRKKVEDAVEEAIHWLDGNQLAEVDEFEDKMKELEGICNPIIAKMYQGGAGGPDMGGGMEDDGPSTGGGAGPKIEEVD
Length649
PositionUnknown
OrganismLactuca sativa (Garden lettuce)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Cichorioideae> Cichorieae> Lactucinae> Lactuca.
Aromaticity0.06
Grand average of hydropathy-0.443
Instability index32.60
Isoelectric point5.13
Molecular weight71163.70
Publications
PubMed=28401891

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08611
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.03|      13|      18|     512|     529|       1
---------------------------------------------------------------------------
  115-  127 (23.47/10.60)	DK.QFSAEEISSMV
  512-  525 (18.56/24.66)	DKgRLSKEEIEKMV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.27|      18|      21|      38|      55|       2
---------------------------------------------------------------------------
   16-   33 (19.08/11.11)	....TTYSCVGVWQHDRveIIA
   38-   55 (32.67/24.26)	NR..TTPSYVAFTDTER..LIG
   60-   78 (24.52/16.38)	NQvaMNPTNTVF.DAKR..LIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.66|      12|      18|     578|     589|       4
---------------------------------------------------------------------------
  578-  589 (21.83/14.47)	DAVEEAIHWLDG
  596-  607 (20.83/13.48)	DEFEDKMKELEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.57|      44|     189|     170|     218|       5
---------------------------------------------------------------------------
  170-  218 (57.55/52.63)	GLNVMRIINePTaAAIAYGLDKKAS..SvGEKNVLIFDLggGTFDVSLLTI
  362-  407 (71.03/43.11)	GKDLCKSIN.PD.EAVAYGAAVQAAilS.GEGNEKVQDL..LLLDVTPLSL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08611 with Med37 domain of Kingdom Viridiplantae
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