<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08583

Description Uncharacterized protein
SequenceMSNFPSLECRSLKRKEHCPPDVYCQRIEQKEDLMCEDFVKDGFKYMKPVRDEYESCKEESRFLSSEAVWNSYYNIMLKKFECSNFQDFKKRQTTNIRDTVIPAIDMYKEQVCDWFKELSNNVSLQNLGRRVPFFKDKEECLHELLINKVPISRALWFVNMSIIQSTAVAETAKKKPRAPQDPTADWSSTLCRMLSRTLEPIYAPIKHNELVALYSDWDYLFSLLIGMYDADIADHWEVIIWLIKLVENVYKEIRGNVSPKSVDSSPVNNSSHSVKCASDFPLKFILHYLVKFGRRFTESELLIRRLLYWCCTTFANVVLTCTGSEFTPSASTFQGILNEYKELNTCPLHRHISLSLGSLITFIILSCPSAAVWNPIPFDTDHTYFRGSPLDHIPHSLIALPLPRGEESIAVRKCLSEVEENIISRSQLVESGWFIEPSSANNGGNVNRHEYHLVREPNPMESLYNRIFNDDSIHEDTATVVTTLCEWAVSPYRIGIYRSIIVACLLEQFKNTFIESTIMTTTTTTTNTTTAIATTAAPNNNSNTLVQPTATTTTVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNTANNNTNANSTTKALKAYQSLQETLIKFLDNCTAQLPSFNGEQSLIENDLMRNLVCLFSELIDREVFDHDNYVRHFIARGVFDTSLHPLAVADNTLQNKLNTSGNPLSCGNNINQSVNTPTSVTRSTTATTSTACHLQSAAQHSVKSEISEDMDRYSMDNPDSVRSESGILSSGVNNSSGLTMTTANLHHTTSTIGNRLMNSNQSGHLHYLIQFPIPQDESYAHEQNQRFQLLYGSVRSRDRARYPIRKLVRDICKLFTKKIYLIDVFHGELGRRKKSKDREREKDNTNSSNNNNNNNSGTNSTNMGTTVTGSTTAAQSTASNAAGTPGSTGGSGSGHRTTNDETRSIDELHEDIMKRFVNLSFYDMEYVLSQCTPVFVKMLNGSNCHSSSNAPTDESVNSIVNTNSPCSASTVTTNQNNNTNNNNSNNLSSVNNQLPASASNVQQSHIYMPVPSSIFLFFELIETSLNITSLILTVIDTLERLKILFENRTHFMTLYMSSLCLRSVGILQRYQNVLFTMGDVSSRLFPTLIEQVRQVKEPTLCGPLERCILIYLNDLFTSNVVIKTRFTPVYGKAHQKVNALLRRVDPNEGMGQFDADYANDLLATTSMDNLTSFRAYAEDLRLKPDSRYSFVCKAIIWICQAKTPERVNYLCSLCAELTSQCSELTPEWIGAFYAILAPRSYVHGYQPLVSTIEPNQVWIYDNLSSLIGTLLSRYCFTISDFLRLVICPAMAQGLDDVSQPVGAQLESIISLASESTVSSLQTTSSVLTPTPEVSTSTNTSTINAPGSSGNPDTLLLNSSPPPPFRISEPLLLTAALQKVTSEFLKSKRRRRRQHNRKAISQVHHVVQRFLEQDILPTSAELHSLPLNALTQLVLREICTVPWIRERFHQMTTNQLIRENVLIDKNFSQSQARRLLHIIYWPYDLSWTDIASTSEGLSGAMCHVLRDLNIWTLKCAQMEFQLLYSQISFSQQGEVLGYLAQSIVQGFQDQVSNWLDSNNCGNFQDGSIGHVDGLPSIELGDNDPVWLLPALIAKLPKSLKVQIIKVTSEVSLFFILAFFYL
Length1662
PositionKinase
OrganismTrichobilharzia regenti (Nasal bird schistosome)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Trematoda> Digenea> Strigeidida> Schistosomatoidea> Schistosomatidae> Trichobilharzia.
Aromaticity0.08
Grand average of hydropathy-0.263
Instability index49.49
Isoelectric point6.20
Molecular weight182255.30
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08583
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     241.65|      90|     124|     775|     897|       1
---------------------------------------------------------------------------
  815-  938 (123.70/106.87)	IPQDESYA....HEQ.NQRF.QLLYgsvrsrdrarYPIRKLVRDICKLFTKkiyLIDVFHGELGRRKKSKDREREKDNTNS..........SNNNNNNNsgtnstnmgttvtgsttaaqSTASNAAGTP..GSTG.GSGSGhR
  939- 1049 (117.96/56.31)	TTNDETRSidelHEDiMKRFvNLSF..........YDMEYVLSQCTPVFVK...MLNGSNCHSSSNAPTDESVNSIVNTNSpcsastvttnQNNNTNNN..................nsNNLSSVNNQLpaSASNvQQSHI.Y
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.78|      19|     124|     104|     122|       2
---------------------------------------------------------------------------
  104-  122 (38.01/26.79)	IDMYKEQVCD......W........FKELSNNV
  225-  257 (23.77/13.82)	IGMYDADIADhweviiWliklvenvYKEIRGNV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.80|      17|     366|     521|     537|       3
---------------------------------------------------------------------------
  521-  537 (27.40/12.66)	TTTTTTNTTTAIATTAA
  900-  916 (31.40/15.51)	TNSTNMGTTVTGSTTAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.91|      14|     520|     258|     271|       5
---------------------------------------------------------------------------
  258-  271 (26.08/16.73)	SPKSVDSSPVNNSS
  765-  778 (24.83/15.52)	SESGILSSGVNNSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.38|      22|     400|    1053|    1091|       9
---------------------------------------------------------------------------
 1066- 1087 (34.90/50.44)	SLNITSLILTVIDTLERLK.ILF
 1095- 1117 (34.47/ 8.93)	TLYMSSLCLRSVGILQRYQnVLF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08583 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GRRKKSKDREREKDNTNSSNNNNNNNSGTNSTNMGTTVTGSTTAAQSTASNAAGTPGSTGGSGSGHRTTNDETRSIDELH
2) LSCGNNINQSVNTPTSVTRSTTATTSTACHL
3) SNCHSSSNAPTDESVNSIVNTNSPCSASTVTTNQNNNTNNNNSNNLSSVNNQL
4) TTSSVLTPTPEVSTSTNTSTINAPGSSGNPDTLLLNSS
5) TTTNTTTAIATTAAPNNNSNTLVQPTATTTTVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNTANNNTNANSTTKA
872
706
984
1364
524
951
736
1036
1401
613










Molecular Recognition Features






MoRF SequenceStartStop




NANANA