<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08563

Description Uncharacterized protein
SequenceMPQCCFAGCHNRTDDGRGLSFFRFPRRDQVRTAAWVQACGRREFAPSQHSRVCSRHFSAVDFERDARADSMGGTHRRLRLKDTAVPTRDPVDNPWQDTDNSPLKRMNKFQPVAPETAPAGLAPPGHTTMDVIVLSEDEDKPSPISSDTEKENNPHGKDPVDGKILLIRLENELRQEEYTLMLLQKLRDSQKSSSPQPTKHYVKSSNSVQVPIPNPQGNITHASAVSTGVTVAVQKNVPVSQPSKAPKVTKVAALQSLEQQCNAKKSVLKKQLERSLEKIPLPRPSAGTGLCEIAFIPSTLTSEFTSLLGLEEVVKNMQEFDPSSTGSQPEPRRTFSPFSCVKCGIDFTPVWKREKVGSSTVICEACLAGTQRSSLQKEYENSVKQVLQQNGAAEREIEREYQEIIANPTKLENYIREQEKKLLATHQAQLAQQQQLAQQAAAQAHSQRYQTKQSVGAQNTGLRTPTHQVSSPCVNNANINGSNNASHQRSRQGTSTPLSNSPVATPSASVTLPQQHLSAAAAAASQHFTPGYQQQQQLTKPTVSVGANAVNTAALMMAATANPALLAATATNQQQQQQRLAAAVLSGLQQQQPQQAQSAVADQFAQIQALFMNSLLLGGSPNNQGSATSRQQLIQQAIQYNLLLQQQQQQAAAAQQAQQAAAAAAQQAQQNALLQLVNALQSNPAAYWTLLQNLLLMGAATNPAGSSGSANKK
Length713
PositionKinase
OrganismSchistocephalus solidus (Tapeworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Cestoda> Eucestoda> Diphyllobothriidea> Diphyllobothriidae> Schistocephalus.
Aromaticity0.04
Grand average of hydropathy-0.577
Instability index57.06
Isoelectric point9.25
Molecular weight77299.78
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-KW

GO - Biological Function
sequence-specific DNA binding	GO:0043565	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08563
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     731.38|     136|     138|     429|     564|       1
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   63-  163 (112.06/39.21)	...............................ERDARADSMGGTHRRLRLKD.TAV.PTrdP...VDNP.WQDTDNSPLKRMNK............FQPVAPET........APAGL..aPP..........GHTTMDVIVLSEdedKPSPISSDTEK..ENNPH...GKDPV.....................DGK
  172-  294 (111.71/39.07)	ELR.....QE.EytlMLLQKLRDSQKS....SSPQ..............PTkHYVkSS..N..SVQVPIPNPQGNITHA...SAVSTGVTvavqkNVPVSQPSkapkvtkvAALQS...LE..........QQCNAKKSVLKK...QLERSL.EKIP..LPRPS.......................AGTGlcEIA
  299-  428 (148.79/54.12)	TLT.....SEfT...SLLGLEEVVKNM....QEFD.PSSTGSQPEPRRT.......FS..PfsCV.KCGIDFT..PVWKREKVGSSTVIC.....EACLAGTQ........RS.SL...QKeyensvkqvlQQNGAAEREIER...EY......QEI..IANPTKL..ENYIREQE........KKLLAT...HQA
  429-  564 (222.65/84.09)	QLA.....QQ.Q...QLAQQAAAQAHS....QRYQTKQSVGAQNTGLRTPT.HQV.SS..P..CVNNANINGSNNASHQRSRQGTSTPLS.....NSPVATPS........ASVTL...PQ..........QHLSAAAAAASQ...HFTPGYQQQQQ..LTKPTVSVGANAVNTAA........LMMAATA..NPA
  565-  704 (136.17/48.99)	LLAatatnQQ.Q...Q.QQRLAAAVLSglqqQQPQQAQSAVADQFA.......QI.QA..L..FMNSLLLGGSPN......NQGSAT..S.....RQQLIQQA........IQYNLllqQQ..........QQQAAAAQQAQQ...AAAAAAQQAQQnaLLQL...VNALQSNPAAywtllqnlLLMGAAT..NPA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08563 with Med12 domain of Kingdom Metazoa
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