<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08555

Description Uncharacterized protein
SequenceMAELMVDIDYKRELNARRDQVEDIFEFEGCKVGRGTYGSVFKAKRKGGNDDREYALKQIEGTGLSMSACREIALLRELKHKNVITLQRVFLNHTNRRVWLLFDFSEHDLWHIIKFHRTSKANKTTFAVYPNMVKSLMYQILNGIDYLHANWVLHRDLKPANILVMGEGPERGRVKIGDLGFARLFYQPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTYEPIFHCRQEDIKTSTPYHKEQLERIFRVMGYPSDEAWPDMRKMPEYPQLMRDSISKKAYGKYSLEGYLEEKKFTIDKYEISLLQSLLTMDPLKRPSAAESMNHEYFKIGEKPNEDAFGNLPIPYPKREFITEDEPDDKQAFNADKNQHQATAGRQCHHQQQQQQQQQQQQQQAQHTVSHYPIQHHQTSSGGGSGPNASASGPGGQSQPQHDRQVRCSARFNAYLVRNQTRLG
Length467
PositionKinase
OrganismSchistocephalus solidus (Tapeworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Cestoda> Eucestoda> Diphyllobothriidea> Diphyllobothriidae> Schistocephalus.
Aromaticity0.10
Grand average of hydropathy-0.700
Instability index45.52
Isoelectric point8.65
Molecular weight54060.72
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP08555
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.44|      15|      35|     156|     170|       1
---------------------------------------------------------------------------
  156-  170 (26.77/17.86)	DLKPANILVMGEGPE
  194-  208 (28.67/19.61)	DLDPVVVTFWYRAPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.04|      28|      41|     397|     425|       2
---------------------------------------------------------------------------
  397-  425 (46.75/32.75)	QQQQQQQQQQQAQHTVSHYPIQhHQTSSG
  440-  467 (49.28/29.77)	QSQPQHDRQVRCSARFNAYLVR.NQTRLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     108.27|      32|      32|     281|     312|       3
---------------------------------------------------------------------------
  252-  282 (19.15/ 6.23)	...........YHKEQLErifrvmGYPSDEAWpdmrKMPEYP
  283-  314 (51.82/26.59)	QLMRDSISKKAYGKYSLE......GYLEEKKF....TIDKYE
  316-  343 (37.29/17.53)	SLLQSLLTMDPLKRPSAA......ESMNHEYF....KI....
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP08555 with CDK8 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AAESMNHEYFKIGEKPNEDAFGNLPIPYPKREFITEDEPDDKQAFNADKNQHQATAGRQCHHQQQQQQQQQQQQQQAQHTVSHYPIQHHQTSSGGGSGPNASASGPGGQSQPQHDRQVRCSARFNAY
332
458

Molecular Recognition Features

MoRF SequenceStartStop
1) ARFNAYLVRNQTRLG
2) TVSHYPIQ
453
411
467
418