<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08543

Description Uncharacterized protein
SequenceMSSFPSLEYRSLKRKEHYPPDVYCQRSEQKEDLMCEDFVKDGFKYTKPVRDEYESCKEESRFLNSDAVWNFYYNVMLKKYECSNFQDFKKRQTTNIRDTVIPAIDMYKEQVSDWFRELSSNVPLQNLGRRVPFFKDKEEILHELLSNKVPITRALWFINISVIQSTAVAETAKKKPRAPQDPTADWSSTLCRLLSRSLEPIYAPVKHNELVSLFNDWDYLFSLLLAMYDSDMADHWEVIIWLIKVAESVNEQICGKSSPSTLDLSPSNRSALTSKCASDFPLKFILHYLIKFGRRFTESELLIRRLLYWCCTTFADVVFACTGPKYAPSVGTLQGILNEYKDLCTCPLHQNISMSLSSLIIFIVLSCPSAAVWNPLPFDTDYAYFKGSPLDHIPHSLVTLPLPPGEESTSIRKCLSEVEEDIIRRSQLVESGWLIEPCSGNNGENVSTSYFILLK
Length455
PositionKinase
OrganismSchistosoma rodhaini
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Trematoda> Digenea> Strigeidida> Schistosomatoidea> Schistosomatidae> Schistosoma.
Aromaticity0.11
Grand average of hydropathy-0.252
Instability index66.96
Isoelectric point5.75
Molecular weight52416.44
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP08543
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.46|      20|      25|     104|     124|       1
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  104-  124 (32.79/23.00)	IDMYKEQvSDWFRELSSN.VPL
  131-  151 (30.67/16.93)	VPFFKDK.EEILHELLSNkVPI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.97|      27|     106|     281|     307|       2
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  281-  307 (46.32/28.28)	PLKFILHYLIKFGRRFTESELLIRRLL
  389-  415 (49.65/30.80)	PLDHIPHSLVTLPLPPGEESTSIRKCL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.84|      23|      28|      37|      62|       3
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   37-   62 (29.52/31.57)	DFVKDgFKYTKPVRdEYEsCKEESRF
   66-   88 (45.31/28.99)	DAVWN.FYYNVMLK.KYE.CSNFQDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.75|      10|      28|     185|     194|       4
---------------------------------------------------------------------------
  185-  194 (19.53/11.40)	DWSSTLCRLL
  216-  225 (19.22/11.11)	DWDYLFSLLL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP08543 with Med12 domain of Kingdom Metazoa

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