<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08542

Description Uncharacterized protein
SequenceMESLYNRIFNDDTIHVDTSIIVITLCEWAVSPYRIGIYRSIIVACLLEQLKNTFYGDSTINSSNISNKDTISLSTTPISTTGSNVNGMTATMTAVTTTITTTTTTTNTTNTSVKHTTTTTNTTNNINIMNSQAYQSLQETLIKFLDNCTIQLPPFNGEQSLIDNHFMRNLVCLFSELIDREVFDHDYYVRYFIARGVFDTSLHPLAVIDHTIPNKMNTNPLSINNSNTINQSVNTPTNITRTTTTTTASTTGGTNIMASTICHSQITTAQHSVKSEFSEDMDRSSVDNPDSVRSESGCINLISLQSNNTQLINHPSLSSSSTSNDQVTTYSNRHLHYLIQFPIPQDECYTHEQNQRFQLLYGSVRSRDRARYPIRKLIHLFNRCXXXXXXXXXXXXXXGELGRRKKSKDRERDKDVNNNNTTNNSNLGLGSFVGQSTGTGTPNSGSGGVGGNGSSHRNGSNNNSNNDETRSIDEIHEDITKRFINLSFYDMEYVLSQCTPVFVKMLNGSNFHSTINPSNEDNNTNTTNITSMNTNSPLSTSSSSSANPPSTTTTTNSNNSNPLSISTSNVQSHIYMPVPSSIFLFFELIETSLNITSLIFTVIDTLERLKILFENRTHFMTLYMSSLCLRTVGILQRYQNILFTMGDLSSRLFPILIEQVRQVKEPTQCGPLERCILIYLNDLFTSNIVIKTRFTPIYGKAHQKVNALLRRIDPSEGIRQFDPDYANDLMTSSTSSSMDNVTSFRAYAEDLRNKPDSRYSFVCKAILWICQAKTIEQVNYLCGLCAELTCQCSELTCEWLGAFYAILAPHSYIHGYSPLINTIDLSQLCIYDNLSSLIGTLLSRYCFTISDFLRLVICPAMAQGLDNITQPVNSQLESIISLACHILHCLFTAESTISSLQTTSNVLTPNPDVNLSNTTTNTTTNTTTNTTVSSSISDNLSSPPFRISEPLLLTAALQKVTSEFLVDVLKMLIVHSDKASVDNQQEDVIDETNTSVGNDNNEDSDGNQDDDDDGGGDEDEEQHDDDENDDNNDGGGGGQDNHIDDLTDIDSEGDHSILRNTNRKRTRTTLQHHQKDKSKRFKSRHNHHRRRSIHRKSTTKVHSIIQRFLEQDIIPTTIELHSLPLNALTQLVLREICTVSWVRERFYQMTPNQLIRENVLIDKNFTQSQARRLLHIIYWPYDIKWIDIALTNDGLSGAMCHILHHLNIWTLKCTQIEFQLLYAQISFSQQTEVLGYLAQSIVHGFQSQIMNWFDLNNNHNHTIAMATNTSTTTATATSNSNSNNNNSNYMNFQESSIGHLINDLPIIELDDNDPVWLFPSLIAKLPKSLKAQIVKVTSEVCFKSVSFYENILLL
Length1354
PositionKinase
OrganismSchistosoma rodhaini
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Trematoda> Digenea> Strigeidida> Schistosomatoidea> Schistosomatidae> Schistosoma.
Aromaticity0.07
Grand average of hydropathy-0.379
Instability index46.10
Isoelectric point5.55
Molecular weight150323.11
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08542
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.81|      17|      18|    1002|    1019|       1
---------------------------------------------------------------------------
 1003- 1019 (33.24/19.10)	DSDGNQDDDDDGGGDED
 1024- 1040 (32.57/13.86)	DDDENDDNNDGGGGGQD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.42|      17|      18|     817|     834|       4
---------------------------------------------------------------------------
  817-  834 (28.26/21.20)	SPLINTIdLSQLC..IYDNL
  835-  853 (27.16/14.96)	SSLIGTL.LSRYCftISDFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     101.93|      15|      18|      96|     110|       5
---------------------------------------------------------------------------
   96-  110 (26.08/ 9.87)	TTTITTTTTTTNTTN
  116-  130 (29.44/12.23)	TTTTTNTTNNINIMN
  545-  559 (24.16/ 8.53)	SANPPSTTTTTNSNN
 1272- 1284 (22.25/ 7.18)	TTATA..TSNSNSNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.01|      15|      18|     237|     251|       6
---------------------------------------------------------------------------
  237-  251 (24.78/12.34)	TNITRTTTTTTASTT
  254-  268 (27.23/14.31)	TNIMASTICHSQITT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.49|      17|      18|     423|     440|       7
---------------------------------------------------------------------------
  423-  440 (26.48/21.09)	NNSNLGLGSFvGQSTGTG
  443-  459 (32.01/20.74)	NSGSGGVGGN.GSSHRNG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.21|      14|      18|      14|      27|       8
---------------------------------------------------------------------------
   14-   27 (25.19/17.43)	IHVDTSIIVITLCE
   35-   48 (25.03/17.26)	IGIYRSIIVACLLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.34|      16|      18|     897|     913|       9
---------------------------------------------------------------------------
  897-  913 (23.30/18.24)	ISSLQTTSNVlTPNPDV
  917-  932 (27.04/16.16)	NTTTNTTTNT.TTNTTV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.64|      18|      20|     758|     776|      11
---------------------------------------------------------------------------
  758-  776 (28.27/26.33)	RYSFVCK..AILwICQAK..TIE
  777-  798 (26.37/16.83)	QVNYLCGlcAEL.TCQCSelTCE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.99|      14|      16|    1098|    1111|      12
---------------------------------------------------------------------------
 1098- 1111 (23.70/16.27)	TTKVHSIIQRFLEQ
 1117- 1130 (23.29/15.85)	TIELHSLPLNALTQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.89|      14|      20|     715|     729|      14
---------------------------------------------------------------------------
  715-  729 (22.35/16.25)	S...EGIRQFDPdYANDL
  735-  751 (19.54/ 8.92)	SssmDNVTSFRA.YAEDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.10|      12|      18|     624|     635|      15
---------------------------------------------------------------------------
  624-  635 (20.67/12.08)	MSSLCLRTVGIL
  645-  656 (20.43/11.86)	MGDLSSRLFPIL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08542 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HSDKASVDNQQEDVIDETNTSVGNDNNEDSDGNQDDDDDGGGDEDEEQHDDDENDDNNDGGGGGQDNHIDDLTDIDSEGDHSILRNTNRKRTRTTLQHHQKDKSKRFKSRHNHHRRRSIHRK
2) MNTNPLSINNSNTINQSVNTPTNITRTTTTTTAST
3) SNFHSTINPSNEDNNTNTTNITSMNTNSPLSTSSSSSANPPSTTTTTNSNNSNPL
4) TPNPDVNLSNTTTNTTTNTTTNTTVSSSISDNLS
5) XXXXXXXXGELGRRKKSKDRERDKDVNNNNTTNNSNLGLGSFVGQSTGTGTPNSGSGGVGGNGSSHRNGSNNNSNNDETRSIDEIHE
975
216
509
908
391
1096
250
563
941
477










Molecular Recognition Features






MoRF SequenceStartStop




NANANA