<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08519

Description Uncharacterized protein
SequenceMESLYNRIFNDDSIHVDTAIIVITLCEWAVSPYRIGIYRSIIVACLLEQLKNTFYGDNNNCTAHLPPFNGEQSLIENNLMRNLVCLFSELIDREVFDHDNYVRYFIARGVFDTSLHPLALIDNTMQNKMNTNPLSINNNNNTINQSVNTPTNITRTTTGSTNMSTASIACHSQTTAQHSVKSEFSEDMDRYSMDNPDSVRSESGIMNLMSLQSNNNQLINHQSFSSSSSLSNNQGLTNSNRHLHYLVQFPIPQDESYAHEQNQRFQLLYGSVRSRDRARYPIRKLIRDICKLFTKKIYLIDVFHGELGRRKRSKDREREKDVNNNNNTANNNNNINSNNLGTTLGLGSLVGQSTTSGTGTSNNGSNVIGNGSSHRSVSNNNSNDETRSIDEVHEDITKRFLNLSFYDMEYVLSQCTPVFVKMLSGSNFHSTVNASNDDNNNNNNSNITSINTNSPLSSSSSSTNTQNTTTTTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQSHIYMPVPSSIFLFFELIETSLNITSLILTIIDTLERLKILFENRTHFMTLYMSSLCLRSVGILQRYQNILFTMGDISCRLFPTLIEQVRQVKEPTQCGPLERCILIYLNDLFTSNIVIKTRFTPIYGKAHQKVNALLRRIDPNDGIGQFDPDYANDLITITSMDNVTSFRAYADDLRNKPDSRYSFVCKAIIWICQAKTIEHVNYLCGLCAELTSQCSELTSEWLGAFYAILAPHSYVHGYSPLINTIDPSQIWIYDNLSSLIGTLLSRYCFTISDFLRLVICPAMAQGLDNVTQPVSVQLKSIISLACHILHCLFTAESTVSSLQTTSNVLTPNPDMNLSNTTTTNTNTTDNLSNSPTSPPFRISEPLLLTAALQKVTSEFLVDVLKMLIVHSDKASVDNNNNNTGFCSQEDIIDETDNATGNDDNNEDSDANQDDDGGDEEHDDENDDNDGGGGGGTLNTQDNLDDLTDIDSEGDNSILRNTTRKRTRTILQPHQKDNNNNKSKRFKSRHNRRLTNRKSISKIHYIIQRFLEHDILPTTIELRTLPLNALTQLVLREICTISWVRERFYQMTSNQLIRENVLIDKNFTQSQARRLLHIIYWPYDITWIDIASTNEGLSGAMCHILHNLNIWTLKCTQIEFQLLYSQISFSQQTEVLGYLAQSIVHGFQSQIINWLDYNNNNTTVSMTTNNNNNNVTTTTTSNNNNTTTATNNNSNYMNFQEGSIGHLIDDLPIIELDDNDPVWLFPALIAKLPKSLKAQIVKVTSEVCLIISLKKVLLLSLLIVRE
Length1298
PositionKinase
OrganismSchistosoma mattheei
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Trematoda> Digenea> Strigeidida> Schistosomatoidea> Schistosomatidae> Schistosoma.
Aromaticity0.07
Grand average of hydropathy-0.384
Instability index45.16
Isoelectric point5.50
Molecular weight142386.75
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08519
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.86|      16|      17|     927|     942|       1
---------------------------------------------------------------------------
  927-  942 (26.68/13.61)	ETDNATGNDDNNEDSD
  944-  959 (27.18/14.00)	NQDDDGGDEEHDDEND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.42|      14|      21|    1190|    1205|       2
---------------------------------------------------------------------------
  323-  336 (26.23/ 8.29)	NNNNNTAN..NNNNIN
 1190- 1205 (23.61/10.90)	NNNNTTVSmtTNNNNN
 1214- 1227 (29.57/10.27)	NNNNTTTA..TNNNSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.30|      13|      16|     180|     195|       3
---------------------------------------------------------------------------
  180-  193 (19.48/20.40)	VKSEfSEDMDRYSM
  199-  211 (22.82/ 9.16)	VRSE.SGIMNLMSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     109.34|      16|      16|     351|     366|       4
---------------------------------------------------------------------------
  221-  240 (25.47/12.18)	HQSFSSSSSLSNNqgltNSN
  351-  366 (28.32/14.57)	GQSTTSGTGTSNN....GSN
  369-  383 (29.05/15.18)	GNG.SSHRSVSNN....NSN
  452-  467 (26.50/13.04)	TNSPLSSSSSSTN....TQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.01|      21|      21|     646|     666|       5
---------------------------------------------------------------------------
  627-  645 (23.28/11.19)	VIKtRFTPIYGKAH...QKVNA
  646-  666 (38.71/23.43)	LLR.RIDPNDGIGQFDPDYAND
  667-  685 (31.03/17.34)	LI..TITSMDNVTSFRA.YADD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.23|      10|      21|     122|     131|       6
---------------------------------------------------------------------------
  122-  131 (18.85/10.10)	DNTMQNKMNT
  140-  149 (17.38/ 8.70)	NNTINQSVNT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.08|      13|      21|     960|     972|       7
---------------------------------------------------------------------------
  960-  972 (25.17/13.07)	DNDGGGGGGTL.NT
  981-  994 (18.91/ 7.98)	DIDSEGDNSILrNT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.10|      22|      22|     831|     852|       8
---------------------------------------------------------------------------
  831-  852 (37.83/19.28)	TVSSLQTTSNVL.TP.NPDMNLSN
  854-  877 (30.27/13.96)	TTTNTNTTDNLSnSPtSPPFRISE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      91.38|      22|      22|    1068|    1089|       9
---------------------------------------------------------------------------
 1016- 1037 (21.53/ 9.84)	..KRFKSRHNRRLT.................nrKSI...SKIHY
 1038- 1075 (20.36/ 8.90)	IIQRFLE...HDILpttielrtlplnaltqlvlREI...CTISW
 1076- 1096 (26.42/13.72)	VRERFYQMTSNQLI...................REN...VLID.
 1097- 1119 (23.07/11.06)	..KNFTQSQARRLL...................HIIywpYDITW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.91|      13|      38|     566|     582|      12
---------------------------------------------------------------------------
  566-  582 (21.70/22.33)	ClrsvGILQR....YQNILFT
  607-  623 (22.21/12.11)	C....GPLERciliYLNDLFT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08519 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DNNNNNTGFCSQEDIIDETDNATGNDDNNEDSDANQDDDGGDEEHDDENDDNDGGGGGGTLNTQDNLDDLTDIDSEGDNSILRNTTRKRTRTILQPHQKDNNNNKSKRFKSRHN
2) GRRKRSKDREREKDVNNNNNTANNNNNINSNNLGT
3) HSTVNASNDDNNNNNNSNITSINTNSPLSSSSSSTNTQNTTTTTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
4) LGSLVGQSTTSGTGTSNNGSNVIGNGSSHRSVSNNNSNDETRSIDEVHE
5) MNTNPLSINNNNNTINQSVNTPTNITRTTTGSTNMSTASIACHS
6) VLTPNPDMNLSNTTTTNTNTTDNLSNSPTSPPF
910
308
429
346
129
841
1023
342
502
394
172
873










Molecular Recognition Features






MoRF SequenceStartStop




1) KRAHRKH
386
392