<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08495
Description |
Uncharacterized protein |
Sequence | MSERSEMEHAVARVGAGTIPLSILIEFISQKVYTDLMLPSKTDLEKKIEIATFFSRTQHLFIRLEALVKWSNSASKVDKCEKISNFLEEQSFFLISTANALSRLLRETLVSARLPPFSVLLAIDIFTNKGYTRLPKSIKNSAFVAESVTEKEKKQALIDLNCIIQNRLSLTQLPHQFRTIKIGMILSSIL |
Length | 190 |
Position | Tail |
Organism | Schistosoma margrebowiei |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Trematoda>
Digenea> Strigeidida> Schistosomatoidea> Schistosomatidae> Schistosoma.
|
Aromaticity | 0.07 |
Grand average of hydropathy | 0.087 |
Instability index | 35.69 |
Isoelectric point | 9.42 |
Molecular weight | 21502.96 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU365082
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:UniProtKB-UniRule
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP08495
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 80.70| 26| 29| 84| 112| 1
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87- 112 (40.90/29.55) LEEQSFFL...ISTANALSRLLRETLVSA
114- 142 (39.81/20.29) LPPFSVLLaidIFTNKGYTRLPKSIKNSA
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|