<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08491
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MSGSEKSKANLTSHVSLFPAPPWQLINKLFSTETPPRPPTPPGSTAYRMFGNFYNSEDAILRSLESQGVRRVYPQTYNRKRELRKINFSILANYLDLLDIITRDPSSCKRAEKLDHLAILFINMHHLVNEYRQHQARDLLREILKYQVNIGAETVEKAEQYLTRADEQLRIAANDLTVPGTPVSTSSSFNLMDNLRNGLNDLGPELAPLLHTVLDETLVSNPVGRYLQPKQGSISLPNQSLEYCSVNVNNPDDYRIPDHIDMALWDFLFQTKDDSEMDVS |
Length | 280 |
Position | Middle |
Organism | Schistosoma margrebowiei |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Trematoda>
Digenea> Strigeidida> Schistosomatoidea> Schistosomatidae> Schistosoma.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.497 |
Instability index | 50.46 |
Isoelectric point | 5.67 |
Molecular weight | 31874.62 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP08491
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 49.05| 12| 23| 19| 37| 1
---------------------------------------------------------------------------
19- 30 (24.54/19.69) PAPPWQLINKLF
39- 50 (24.51/ 6.30) PTPPGSTAYRMF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 56.80| 16| 23| 167| 182| 2
---------------------------------------------------------------------------
167- 182 (27.97/17.63) EQLRIAANDLTVPGTP
193- 208 (28.83/18.37) DNLRNGLNDLGPELAP
---------------------------------------------------------------------------
|