<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08483

Description Uncharacterized protein
SequenceLKCHPLSCRPGLQAKDDNTLLQDMFSSNLRTWNFLSQETENNNELLAFNQEYVENKVEELQFAIRREKIEQVKIEACLSLLRNSSIDINEFISEARIAAEAAAVAVQLNNNDRNSGLLNHSTPSRRSIIRPLGEGSSDSAASSSGVNQFIDHDSRLLSDWDQPYAPYGSEPLGRNTTTYPFQRSFNVDDNDDNGDVESTNRLYRNGINNWSSTFPRPSTSGQMDNSTDKTPHPTYRSSSQTSTKLNCLNQNNLFPNNNETRVKHDYQNVSQISSRTHDDITVHRSTINNDNNSNKSHPNDTFNRFSSIRIGSSNNLTNNKDDIDFEVIWSENNRLRRATVVHEFRAKKPNELDLVVHETVVLLNNEPQNGWIKVRSLIDGNEGLVPISYLKLSNIDVPKHNSKIIMNGDNSNQTISTLHTSGNDIVHSKLTNCSEDSDQKNSKKPNQVDPTFLSLPPEIDPPRLLCTDEVSGHEMSKPPLSGSFVRSLIDFRGTNPDELSFKAGAVIRVIGRAPIINDLVNNSSTATRRDQLTSMSGYSIDDGWWEGDLLVAESNKNDEDQQFYSIRGVFPSMLVQSLSSVDSELWTVRWNNIVPLPLGNSLEESDNSENQNNSNKNNISSSKISAKQLHTTINHHNNNMVNNCSVDVNKSKKNCHAIDEEDYIQLHSNVLPSSQTVQVKSSTCQIHSSPSESIKLPHNSLSDDTKHSAPNNPVTSRHPHQNSQCLHHRHHNRHHEYSKTDEIPRKCFSKRSRDTGNSTCSVDTPIDMKQNKVSSIIDDSRWPKKEKQSPKGPGLYKSLRKVGSALLRLPDGFQQETPRSRNRKARSVSSEIEDPDKTVTVPNSPSAAVLSDDKWTSVRRKRNGKKKAVGETQLVTKSLEETVSETRLHCVSRQTSLSGFYLNYEMFASQPNIKPTHIPPIMECPPMPHPAMNVNFPTFYSGSFVQNNISSLAQESLYEIQRLRLLLTNLLTSIQSDEKDPEEKNKIVDENFMLFNRNGSTKCENIPSPLFTTGEGKTNGIVPECRNNLPQTLGTKNLSCEKLALHKIVNQISDVFNNLDHLASRMQVNRLSGRPSDHGLQNALSLFNTVEQLEFSRNSWLYESSLSQYMGTDDHGKESDCRRVDWLMDRIEAERWSHRYWGRTRTVLEGLLACSAFRRSHLNTDHSRRRTDFLNIINRDYGADLEHLLNELNVNLPDLTITLIEPSSVVSVAHLRVGEIMQCFVTFRQLNPERIIVRGVSEPMIIKTHSDFPNNNLNIEEKPLSLATDELLSDSGLDSLPKIRDTVVSLLSPDSKARSLPDHRQQRSSKLIRFCSIHQSKLDLFTPSRHPLFRRITSLAQCALLHFSNEYKPPSAIRGFCAWLHSYRDLFSAPCCRCGQLLGQNVELPLWRSYPQMRKDNSRSMEPQHEHCQAII
Length1416
PositionTail
OrganismSchistosoma margrebowiei
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Trematoda> Digenea> Strigeidida> Schistosomatoidea> Schistosomatidae> Schistosoma.
Aromaticity0.06
Grand average of hydropathy-0.724
Instability index50.48
Isoelectric point6.78
Molecular weight160246.79
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08483
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     172.56|      51|      94|     347|     401|       1
---------------------------------------------------------------------------
  347-  395 (69.02/47.84)	.......KKPNELDlvvhETV..VLLNNE....................PQNGWIKVRSLIDGNEGLVP..ISYLKLSNI
  396-  433 (54.81/29.63)	DVPKHN...............skIIMNGD....................NSNQTISTLH.TSGND......IVHSKLTNC
  436-  501 (48.73/25.50)	DSDQKNsKKPNQVD....PTF..LSLPPEidpprllctdevsghemskpPLSGSF.VRSLID.FRGTNPdeLSF......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     330.30|     105|     359|     669|     849|       2
---------------------------------------------------------------------------
  211-  334 (158.85/54.95)	SSTFPRPSTSGQMDnstdktphptyrSSSQTSTKL..NCLNQNNLF..PNNNETRvKHDYQNVSQISSRTHDDitvHRSTINNDNNSNK...SHPNDTFNrfSSIRIGSSNNLTNNK..DDIDfEVIWSENNR
  674-  787 (171.45/147.22)	SQTVQVKSSTCQIH............SSPSESIKLphNSLSDDTKHsaPNNPVTS.RHPHQNSQCLHHRHHNR...HHEYSKTDEIPRKcfsKRSRDTGN..STCSVDTPIDMKQNKvsSIID.DSRWPKKEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.69|      28|     559|     516|     543|       3
---------------------------------------------------------------------------
  516-  543 (48.39/32.01)	INDLVNNSSTATRRDQLTSMSGYSIDDG
 1052- 1079 (48.29/31.93)	ISDVFNNLDHLASRMQVNRLSGRPSDHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     193.67|      61|     580|       5|      67|       6
---------------------------------------------------------------------------
    5-   67 (99.23/62.37)	PLSCRPGLQAKD.....DNTLLQDMFSSNLRTWNFLSQETENNNELLafNQEYVE.NKVEELQFAIRRE
  595-  661 (94.43/53.60)	PLPLGNSLEESDnsenqNNSNKNNISSSKISAKQLHTTINHHNNNMV..NNCSVDvNKSKKNCHAIDEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.06|      34|      37|     100|     133|       8
---------------------------------------------------------------------------
  100-  133 (57.60/39.30)	EAAAVAVQLNN.NDRNSGLLNH.STPSRRSIIRPLG
  138-  173 (51.46/34.13)	DSAASSSGVNQfIDHDSRLLSDwDQPYAPYGSEPLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.26|      43|      85|    1166|    1208|      12
---------------------------------------------------------------------------
 1166- 1208 (72.14/49.05)	HSRRRTDFLNIINRDYGADLEHLLNELNVN....LPDLTITLIEPSS
 1249- 1295 (65.12/43.47)	HSDFPNNNLNIEEKPLSLATDELLSDSGLDslpkIRDTVVSLLSPDS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08483 with Med27 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GNSLEESDNSENQNNSNKNNISSSKISAKQLHTTINHHNNNMVNNCSVDVN
2) LLRLPDGFQQETPRSRNRKARSVSSEIEDPDKTVTVPNSPSAAVLSDDKWTSVRRKRNGKKKAVGETQLVT
3) SQTVQVKSSTCQIHSSPSESIKLPHNSLSDDTKHSAPNNPVTSRHPHQNSQCLHHRHHNRHHEYSKTDEIPRKCFSKRSRDTGNSTCSVDTPIDMKQNKVSSIIDDSRWPKKEKQSPKGPGLYKSLRK
4) WDQPYAPYGSEPLGRNTTTYPFQRSFNVDDNDDNGDVESTNRLYRNGINNWSSTFPRPSTSGQMDNSTDKTPHPTYRSSSQTSTKLNCLNQNNLFPNNNETRVKHDYQNVSQISSRTHDDITVHRSTINNDNNSNKSHPNDTFNRFSSIRIG
599
806
674
160
649
876
801
311










Molecular Recognition Features






MoRF SequenceStartStop




1) GLYKSLRKVG
794
803