<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08480

Description Uncharacterized protein
SequenceMSSFPSLEYRSLKRKEHCPPDVYCQRSEQKEDLMCEDFVKDGFKYTKPVRDEYESCKEESRFLNSDAVWSFYYNVMLKKYECSNFQDFKKRQTTNIRDTVIPAIDMYKEQVCDWFRELSSNVPLQNLGRRVPFFKDKEEILHELLSNKVPITRALWFINISVIQSTAVAETAKKKPRAPQDPTADWSSTLCRLLSRSLEPIYAPVKHNELISLFNDWDYLFSLLLAMYDSDMADHWEVILWLIKVAETLTSKCASDFPLKFILHYLIKFGRRFTESELLIRRLLYWCCTTFADVVFACTGSKYASSVGTLQSILNEYKDLCTCPLHQSISMSLSSLIIFIVLSCPSAAVWNPIPFDTDYAYFKGSPLDHIPHSLVALPLPLGEESTSIRKCLSEVEEDIIRRSQLVESGWLIEPCSGNNGENVSPSFILIE
Length431
PositionKinase
OrganismSchistosoma margrebowiei
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Trematoda> Digenea> Strigeidida> Schistosomatoidea> Schistosomatidae> Schistosoma.
Aromaticity0.12
Grand average of hydropathy-0.178
Instability index68.37
Isoelectric point5.55
Molecular weight49803.66
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP08480
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.59|      24|      28|     101|     124|       1
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   76-   94 (24.42/11.25)	.....MLKKYECSNFQDFKKR.QTT
  101-  124 (44.63/25.54)	IPAIDMYKEQVCDWFRELSSN.VPL
  131-  151 (28.54/14.16)	VPFFK.DKEEI...LHELLSNkVPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.17|      14|      23|     345|     367|       2
---------------------------------------------------------------------------
  345-  358 (27.41/31.91)	PSAAVWNPIPFDTD
  371-  384 (24.76/ 7.40)	PHSLVALPLPLGEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.89|      17|      22|     298|     314|       3
---------------------------------------------------------------------------
  298-  314 (28.79/20.68)	CTGSKYASSVGTLQSIL
  321-  337 (31.10/22.93)	CTCPLHQSISMSLSSLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.94|      20|      22|     388|     407|       4
---------------------------------------------------------------------------
  388-  407 (31.96/19.96)	IRKCLSEVEEDIIRRSQLVE
  412-  431 (34.97/22.47)	IEPCSGNNGENVSPSFILIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.75|      10|      28|     185|     194|       5
---------------------------------------------------------------------------
  185-  194 (19.53/13.22)	DWSSTLCRLL
  216-  225 (19.22/12.88)	DWDYLFSLLL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP08480 with Med12 domain of Kingdom Metazoa

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