<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08479

Description Uncharacterized protein
SequenceMETDMKRINKNWIEQERKTQDRVVWRMLIGGLCFIRSNRRKYIERLVRLLDILDRHEYHLVREPNPMESLYNRIFNDDSIHVDTAIIVITLCEWAVSPYRIGIYRSIIVACLLEQLKNTFYGDNSINSSNIINKDTVSLSTAPVNTVSTTGSNVNGVTTTMTAVTTTATTTTTTTANTTSVKNTTNINNMNIMSSQAYQSLQETLIKFLDNCTAHLPPFNGEQSLIENNLMRNLVCLFSELIDREVFDHDNYVRYFIARGVFDTSLHPLALIDNTMQNKMNTNPFSINNNNNNNNNNNTINQSVNTPTNITRTTTGGTNMSTASITCHSQTTAQHSVKSEFSEDMDRYSMDNPDSVRSESGIMNLMSLQSNNQPINHQSFSSSSSLSNNQGITNSNRHLHYLVQFPIPQDESYAHEQNQRFQLLYGSVRSRDRARYPIRKLIRDICKLFTKKIYLIDVFHGELGRRKRSKDREREKDVNNNNNTANNNNINSNNLGTTLGLGSLVGQSTTSTGTGTSNNGSNIIGNGSNHRSVSNNNSNDETRSIDEVHEDITKRFINLSFYDMEYVLSQCTPVFVKMLSGSNFHSTVNASNDDNNSNSNITSINTNSPLSSSSSTNTQNTTTTISSSSNSFVTTVSNNNNNPLSMTTSNTQSHIYMPVPSSIFLFFELIETSLNITSLILTIIDTLERLKILFENRTHFMTLYMSSLCLRSVGILQRYQNILFTMGDISCRLFPTLIEQVRQVKEPTQCGPLERCILIYLNDLFTSNIVIKTRFTPIYGKAHQKVNALLRRIDPNDGIGQFDPDYANDLITITSMDNVTSFRAYADDLRNKPDSRYSFVCKAIIWICQAKTIEHVNYLCGLCAELTSQCSELTPEWLGAFYAILAPHSYVHGYSPLINTIDPSQIWIYDNLSSLIGTLLSRYCFTISDFLRLVICPAMAQGLDNVTQPVSVQLKSIISLACHILHCLFTAESTVSSLQTTSNVLTPNPDMNLSNTTTTTTNTTDNLSNSPTSPPFRISEPLLLTAALQKVTSEFLVDVLKMLIVHSDKASVDNNNNTGFCSQEDIIDETDNGTGNDDNNEDSDANQDDDGGDEEHDDENDDNDGGGTLNTQDNLDDLTDIDSEGDNSILRNTTRKRTRTILQQHQKDNNKSKRFKSRHNRRHINRKSISKIHYIIQRFLEHDILPTTIELRTLPLNALTQLVLREICTISWVRERFYQMTSNQLIRENVLIDKNFTQSQARRLLHIIYWPYDITWIDIASTNEGLSGAMCHILHNLNIWTLKCTQIEFQLLYSQISFSQQTEVLGYLAQSIVHGFQSQIINWLDYNNNNTTVSMTSNNNNNITTTTTSNNNNTNNNANNSNYMNFQEGSIGHLIDDLPIIELDDNDPVWLFPALIAKLPKSLKAQIVKVTSEVCLIISFKKLLLLLLFIVRIFFIIHFLTIFANVKLIAGFGWSNRTLLAGTLVLLGLIMSERLVEER
Length1479
PositionKinase
OrganismSchistosoma margrebowiei
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Trematoda> Digenea> Strigeidida> Schistosomatoidea> Schistosomatidae> Schistosoma.
Aromaticity0.07
Grand average of hydropathy-0.350
Instability index45.66
Isoelectric point5.84
Molecular weight167127.84
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08479
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.44|      15|      16|     336|     351|       1
---------------------------------------------------------------------------
  336-  351 (23.05/22.70)	SVKSEfSEDMDRYSMD
  355-  369 (26.39/19.12)	SVRSE.SGIMNLMSLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.43|      16|      21|    1064|    1084|       4
---------------------------------------------------------------------------
 1064- 1084 (25.90/22.86)	EDiidetDNG.TGNDDNNEDSD
 1088- 1104 (26.53/12.24)	DD.....DGGdEEHDDENDDND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.01|      11|      21|    1327|    1342|       5
---------------------------------------------------------------------------
  294-  304 (20.21/ 7.30)	NNNNNTI....NQSV
 1327- 1341 (16.80/ 9.49)	NNNNTTVsmtsNNNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.21|      22|     351|     992|    1017|       7
---------------------------------------------------------------------------
  139-  160 (33.87/ 6.95)	LSTAPVNTVSTTGSNVNGVTTT
  993- 1014 (39.35/21.97)	LSNTTTTTTNTTDNLSNSPTSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.91|      51|     867|     387|     505|       8
---------------------------------------------------------------------------
   54-  123 (76.62/20.56)	DRHEYHLVREPNPM.ES...........LYNRIFNDDSihvdtaiivitlcewAVSPYRiGIYRSIivaC.LLEQ...LKNTFYGD
  396-  462 (72.28/124.14)	NRHLHYLVQFPIPQdESyaheqnqrfqlLYGSVRSRDR...............ARYPIR.KLIRDI...CkLFTKkiyLIDVFHGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.37|      17|      18|     793|     810|       9
---------------------------------------------------------------------------
  793-  810 (28.90/22.59)	IDPNDGIGQFDPdYANDL
  813-  829 (30.47/18.46)	ITSMDNVTSFRA.YADDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.22|      25|     867|     480|     505|      10
---------------------------------------------------------------------------
  480-  505 (42.94/18.55)	NNNNTANNNNiNSNNLGTTLG.LGSLV
 1350- 1375 (44.29/16.16)	NNNNTNNNAN.NSNYMNFQEGsIGHLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.29|      15|      21|    1201|    1219|      11
---------------------------------------------------------------------------
 1201- 1219 (18.16/20.29)	QLVlREICTISwvrERFYQ
 1224- 1238 (26.12/12.80)	QLI.RENVLID...KNFTQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.30|      13|     351|     907|     924|      13
---------------------------------------------------------------------------
  895-  907 (24.01/ 7.82)	SPLINTIDPSQIW
  913-  925 (22.30/20.47)	SSLIGTLLSRYCF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.78|      13|     517|     875|     889|      14
---------------------------------------------------------------------------
  875-  889 (23.34/28.17)	PEWLgaFYAILA..PHS
 1388- 1402 (22.44/17.22)	PVWL..FPALIAklPKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.48|      10|     517|     528|     537|      15
---------------------------------------------------------------------------
  528-  537 (19.21/10.66)	SNHRSVSNNN
 1047- 1056 (18.27/ 9.72)	SDKASVDNNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.11|      11|      21|    1131|    1141|      17
---------------------------------------------------------------------------
 1131- 1141 (18.59/10.88)	RNTTRKRTRTI
 1154- 1164 (20.53/12.84)	RFKSRHNRRHI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.86|      11|      20|     607|     617|      19
---------------------------------------------------------------------------
  607-  617 (18.74/ 8.25)	NSPLSSSSSTN
  630-  640 (19.12/ 8.58)	NSFVTTVSNNN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08479 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DNNNNTGFCSQEDIIDETDNGTGNDDNNEDSDANQDDDGGDEEHDDENDDNDGGGTLNTQDNLDDLTDIDSEGDNSILRNTTRKRTRTILQQHQKDNNKSKRFKSRHN
2) GQSTTSTGTGTSNNGSNIIGNGSNHRSVSNNNSNDETRSIDEVH
3) GRRKRSKDREREKDVNNNNNTANNNNINSN
4) MNTNPFSINNNNNNNNNNNTINQSVNTPTNITRTTTGGTNMSTASITCHS
5) STVNASNDDNNSNSNITSINTNSPLSSSSSTNTQNTTTT
6) TTAQHSVKSEFSEDMDRYSMDNPDSVRSESGIMNLMSLQSNNQPINHQSFSSSSSLSNNQGIT
7) VLTPNPDMNLSNTTTTTTNTTDNLSNSPTSPPF
1053
506
464
280
586
331
984
1160
549
493
329
624
393
1016










Molecular Recognition Features






MoRF SequenceStartStop




NANANA