<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08459

Description Uncharacterized protein
SequenceMVAGDKRLVHTPFVPSEYWIPCAPFVWDQGFPTLLGGLSISTSLVKAPDIHILKGIKNFWKHKNDEDKESILLHHSILLTHPTFFSLLQICLPDSDFIIESLYEQIEYFLLNSRHLIDHVPENLHTRQIIQNCLKYRLILIGQKFHIIQLDIDMTIRWITLLTQLISYGIIEPESNSILFYIVYDMLQLLIHTLTARTGIEGKHYQMIAKKLRRELLEHPSNTGKERFNPWEIYDPSKQPLLLSIHGAINTESILSRIEEQANRLIRHDHFHRMYRPPEFYMIPIYPQTFDEDISMNHVKLSDVGEHDHPDIIKMIKTENSNNNNDTTNSITNNTSISSIYNKNHNSNSMDVMRESQILSLNDMTQLSETNLSECSNQFLSINGSNNNNNDINIRSGDSNSNYLQSTSGVLYDQKHNISSISCHSTNNLMFNESNSSIKSVNQIDCGNTNIMMSMMMMTSSGSTTVDTATNNSNSMQIGRGKLLNTRNDIEINDKLSLNNRINAFQSSSSGSLGGGTVGSGIGVVSSSTSSLQIHSHPQQIHGHHHHHHQQQQQIHLNSDQAYNNSTRKLPSQQTVLNDYSNPNELDQRPMNNVNHCVTLAGHMNTITYPLSHHHNHQMDVNLHKTNKLLGMEYNDRLIASQSSTSSQQQIQLNPTGTSSIPPPSNNATMLSTPMNNSVVAGHVLTSAKTATTTTKRKRGSGRRGGGGNITSDRNSIRPSGATTRGGMHTTGSVNVVGYERMNNNSTNNSSVNLYSYNIINPEQQINESNHQWTNKQNVYNMNLLEMQQQQQQPPSSTRGHHQQQHLANLSGFLRNRHVFDQSQLSSQFNQSNTHLVDSPSGSLRRHLTTSGGGGGNVARSMQQSSQQQSHQILSHPTGTPQQLPPGMPNPPPYPISNHQSQQYSFRAPPSDEANYMMNTNESSIDEQFKRQSINPVMNSIHQSGTTIMSRSSTYESPASHLQTDVPSQQQHMSYIPSQVDTPLNQSRIHSRIINQSQSNQMIRSDITPTTVINTGNNNQPSHMSNLPHSSYSRYTGY
Length1038
PositionKinase
OrganismSchistosoma curassoni
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Trematoda> Digenea> Strigeidida> Schistosomatoidea> Schistosomatidae> Schistosoma.
Aromaticity0.06
Grand average of hydropathy-0.690
Instability index57.27
Isoelectric point7.05
Molecular weight116707.45
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08459
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     115.56|      21|      63|     537|     557|       1
---------------------------------------------------------------------------
  534-  554 (42.10/21.01)	IHSH............PQQIHGHHHHHHQ....QQQQ
  555-  575 (27.18/10.30)	IHLN............SDQAYNNSTRKLP....SQQT
  873-  903 (21.62/ 6.31)	ILSHptgtpqqlppgmPNPPPYPISN.HQ....SQQ.
  948-  971 (24.65/ 8.48)	IMSR............SSTYESPAS.HLQtdvpSQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     234.28|      48|     135|     485|     532|       2
---------------------------------------------------------------------------
  340-  380 (53.86/26.26)	.........IY..NKNHNSNSMDVMRESQILSLNDMTQLSETNLSE.CSN...QFL
  387-  429 (62.35/31.69)	NNNN.DIN.IR.....SGDSNSNYLQ.STSGVLYDQK..HNISSIScHST...NNL
  432-  476 (41.58/18.41)	NESNsSIKsVNqiDCGNTNIMMSMMMMTSSGS..........TTVD.TATnnsNSM
  485-  532 (76.50/40.74)	NTRN.DIE.IN..DKLSLNNRINAFQSSSSGSLGGGTVGSGIGVVS.SST...SSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.44|      14|      18|     733|     749|       3
---------------------------------------------------------------------------
  744-  761 (12.15/14.27)	NNSTNN..sSVNLysYNiIN
  767-  783 (22.29/10.98)	NESNHQwtnKQNV..YN.MN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.12|      10|      18|     699|     708|       5
---------------------------------------------------------------------------
  699-  708 (22.26/13.17)	RGSGRRGGGG
  718-  727 (19.86/10.93)	RPSGATTRGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.14|      16|      18|     986|    1001|       6
---------------------------------------------------------------------------
  986- 1001 (28.05/13.44)	QSRI.HSRIINQSQSNQ
 1004- 1020 (24.08/10.55)	RSDItPTTVINTGNNNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.09|      10|      18|     915|     924|       9
---------------------------------------------------------------------------
  915-  924 (19.03/10.25)	NYMMNTNESS
  935-  944 (19.06/10.29)	NPVMNSIHQS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08459 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GHMNTITYPLSHHHNHQMDVNLHKTNKLLGMEYNDRLIASQSSTSSQQQIQLNPTGTSSIPPPSNNATMLSTPMNNSVVAGHVLTSAKTATTTTKRKRGSGRRGGGGNITSDRNSIRPSGATTRGGMHTTGSVNVVGYERMNNNSTNNSSVNLYSYNIINPEQQINESNHQWTNKQNVYNMNLLEMQQQQQQPPSSTRGHHQQQHLANLSGFLRNRHVFDQSQLSSQFNQSNTHLVDSPSGSLRRHLTTSGGGGGNVARSMQQSSQQQSHQILSHPTGTPQQLPPGMPNPPPYPISNHQSQQYSFRAPPSDEANYMMNTNESSIDEQFKRQSINPVMNSIHQSGTTIMSRSSTYESPASHLQTDVPSQQQHMSYIPSQVDTPLNQSRIHSRIINQSQSNQMIRSDITPTTVINTGNNNQPSHMSNLPHSSYSRYT
2) HDHPDIIKMIKTENSNNNNDTTNSITNNTSISSIYNKNHNSNS
3) MMTSSGSTTVDTATNNSNSMQIGRGKLLNT
4) VVSSSTSSLQIHSHPQQIHGHHHHHHQQQQQIHLNSDQAYNNSTRKLPSQQTVLNDYSNPNELDQRPMNNVNHCVTL
602
307
457
524
1036
349
486
600










Molecular Recognition Features






MoRF SequenceStartStop




NANANA