<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08409

Description Uncharacterized protein
SequenceMEDSIQQVSSFPPPPIHYINHYTDKNIADGLALPPPPPVQGHYSMFGVGYSTDDPIIQSLESQNVRRLFQIGPNFDRKVEMKKLNHSILANFLDLLEILVRCPSSPERERKIEDLQLLFINMHHLINEYRPHQARETLKLMLEVQGQERRIVVKRFVAQFDAVYRNLQQCLNDIPASCAGATSRDAELSKFLNDLPYDRDMFSERLVYQQSPRRCFACDECGKSFRSIEELVFHVENCVLDSLEMTASTVLNESNGLGKDETDKPNGDESSSDVQAGNDIFKSQSSGKNDHSTTGNVDGYSYEEPSSYMPGREDTSTSHSYFGGNNREAGQVTLANPPNYDDEDIEPPPLLELAEPPVKKYRRSFPVGEDGKQIRPKMECPTCGLVLYRHNFSTHYRIHTGELPFQCSFCDKRFRTSSALTVHTRCHTGEKPYTCTHCDYSCITKRNLDRHVINNHVKRSRRAMLRGGHQSFMRTRLPQPRIGCTDVGMMPTNSVEAQTESLDDNVVIVAAAADRIDMMDGQMLQVGSVEESEVRDNDGNGPIVFQTVHQMGTEGDEEETTVRSNNMAVERPPPMGSMQQLRLS
Length584
PositionMiddle
OrganismSoboliphyme baturini
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Dioctophymatida> Dioctophymatoidea> Soboliphymatidae> Soboliphyme.
Aromaticity0.07
Grand average of hydropathy-0.658
Instability index60.66
Isoelectric point5.49
Molecular weight66049.34
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP08409
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.37|      23|      26|     389|     411|       2
---------------------------------------------------------------------------
  389-  411 (48.79/35.50)	RHNFST....HYRIHTGELPFQCSFCD
  413-  439 (43.57/30.82)	RFRTSSaltvHTRCHTGEKPYTCTHCD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.30|      10|      18|     166|     175|       3
---------------------------------------------------------------------------
  166-  175 (20.09/15.08)	NLQQCLNDIP
  187-  196 (18.21/12.94)	ELSKFLNDLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.26|      17|      26|     522|     538|       5
---------------------------------------------------------------------------
  522-  538 (29.68/22.48)	QMLQVGSVEESEVRDND
  550-  566 (30.57/23.39)	QMGTEGDEEETTVRSNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.11|      16|      22|     281|     302|       6
---------------------------------------------------------------------------
  282-  302 (24.89/29.29)	KSQSS...GKNDHSTtgnvdGYSY
  303-  321 (25.21/10.52)	EEPSSympGREDTST.....SHSY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      58.83|      14|      26|     106|     119|       7
---------------------------------------------------------------------------
   73-   92 (14.40/ 7.89)	PNFDRKVEmkklNHSILanF
  106-  119 (24.28/19.01)	PERERKIE....DLQLL..F
  131-  142 (20.15/14.36)	PHQAR..E....TLKLM..L
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.40|      19|      98|     358|     384|       8
---------------------------------------------------------------------------
  341-  361 (29.24/21.31)	DDEDIEPPplLELAEPPVKKY
  370-  388 (34.17/10.60)	DGKQIRPK..MECPTCGLVLY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP08409 with Med7 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) DGQMLQVGSVEESEVRDNDGNGPIVFQTVHQMGTEGDEEETTVRSNNMAVERPPPMGSMQQLRLS
2) VLNESNGLGKDETDKPNGDESSSDVQAGNDIFKSQSSGKNDHSTTGNVDGYSYEEPSSYMPGREDTSTSHSYFGGNNREAGQVTLANPPNYDDEDIEPPPLLELAEPPVKKYRRSFPVG
520
250
584
368

Molecular Recognition Features

MoRF SequenceStartStop
1) IHYINHY
16
22