<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08356

Description Uncharacterized protein
SequenceMLGERHYCIVGRGTYGHVFKAQPKVPSAKYPAKEYALKLIEGQGFSMSACREIALLRELKHPNLICLQRVFLTNEKKVWLLLDYAEHDLWHIIKYHRGAKAKKMPVMVPKGMVKSILYQILDGIHYLHSNWVLHRDLKPANILVMGDAPGVHRGRVKIADMGFARIFYNPLKPLAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPVFFCKEEDIKAQSPYHYDQLKRIFTVMGYPQESEWNDFKKMPDYHKLSKLSEPILHFRTAFPNCSMTRYMEKHKIESDSPQFKLLVKLLTMDPNKRISCKDAMEEPYFKMDPKPTEDVFYKFEIPYPKRESLPDQATNPQVSFYRIFLHVNQAMNQQLDSEPVNKRLRMGGQQVGFIVF
Length398
PositionKinase
OrganismHeligmosomoides polygyrus bakeri (Parasitic nematode) (Heligmosomoides bakeri)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Strongylida> Trichostrongyloidea> Heligmosomatidae> Heligmosomoides.
Aromaticity0.12
Grand average of hydropathy-0.306
Instability index55.14
Isoelectric point9.19
Molecular weight46370.80
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08356
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.87|      18|      31|     295|     325|       2
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  301-  325 (29.74/45.09)	FKllvklltMDPN..............KRISCKDAMEEP
  327-  358 (24.14/ 8.34)	FK.......MDPKptedvfykfeipypKRESLPDQATNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.16|      26|      37|     104|     139|       3
---------------------------------------------------------------------------
  104-  139 (38.48/46.60)	MPVM.....VPKGMVKsilyqILD.GIHYLHSNwvlhrDLKP
  142-  173 (37.68/21.59)	ILVMgdapgVHRGRVK.....IADmGFARIFYN.....PLKP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08356 with CDK8 domain of Kingdom Metazoa
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