Description | Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MAFIAEITFPDGQLVGGSGSGLTPVVSGPETSEEQKKRFEIECEFVQSLANPHYLNFLAQRGYFKEPYFINYLKYLLYWKRQEYARLQYTTAEDDDEQQQQQQQEKKPPTSTAP |
Length | 114 |
Position | Middle |
Organism | Gongylonema pulchrum |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Spiruroidea> Gongylonematidae> Gongylonema. |
Aromaticity | 0.14 |
Grand average of hydropathy | -0.803 |
Instability index | 67.90 |
Isoelectric point | 4.84 |
Molecular weight | 13222.55 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro |
Binary Interactions |
Repeats | >MDP08330 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) FPDGQLVG 2) QKKRFEI 3) VVSGPE 4) YFKEPYFINYLKYLLYWKRQEYARLQYTTAEDDDEQQQQQQQEKKPPTSTAP | 9 35 25 63 | 16 41 30 114 |
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