<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08316

Description Uncharacterized protein
SequenceMPRQQASLKPMFGAGQQSSSNTQQPAGVNVALEAGSEWEVRKVGPLDYLGRVAKMAGKVDWLELAGADATFGNPDSLPRDNDGDDDGDDADEEMELDEVENVVVGMEDRKTPEAGPWHGVAKYYHHSLQQVNTLADMVAILKTSGMEALTVADTFEVQHNMQDMIQQSKQFQWVTRRKGLGEAVAVFEYGQKMRAKISAENDIEKELFFRELRKMREFWRVRKTGDIMYGDLGYKIFGSKYKPRDLFDIRQRAGISSSAGSDSIGATSLSTADSYLQIQLPCHLLRRASVAVSIETDGDDPKDLFATSENELDCLKLCQEKASEVPWPKALNWAQENLVCKDIFKQVLFHAVVLKKHVAVVRGEVLVVSLLDKVLLRVELAYHPFEDGPLPAAGDAYLNRTLRHLYFNDLCVRDARQQTFVAMPLTTLPDTLDLRGPYAMNDEEVIQSSLNFSFLWT
Length457
PositionHead
OrganismGongylonema pulchrum
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Spiruroidea> Gongylonematidae> Gongylonema.
Aromaticity0.08
Grand average of hydropathy-0.365
Instability index35.75
Isoelectric point5.04
Molecular weight51230.44
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08316
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.02|      35|     137|     200|     237|       1
---------------------------------------------------------------------------
  169-  214 (37.39/34.62)	KQFqWVTRRKGlgeavaVFEYGQkMRAKISaENDIEKELFfrELRK
  216-  251 (60.63/41.14)	REF.WRVRKTG......DIMYGD.LGYKIFgSKYKPRDLF..DIRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     225.80|      63|     214|      80|     151|       2
---------------------------------------------------------------------------
   80-  142 (112.28/57.80)	DNDGDDDGDD.ADEEMELDEVENVVVGMEDRKTPEAGPWHG.........VAK.YYHHSLQQV..NTLADMVAILK
  295-  362 (80.16/38.11)	ETDGDDPKDLfATSENELD.....CLKLCQEKASEV.PWPKalnwaqenlVCKdIFKQVLFHA..VVLKKHVAVVR
  375-  410 (33.36/19.87)	.................LLRVELAYHPFEDGPLPAAGD..............A.YLNRTLRHLyfNDL........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.00|      23|     276|     146|     168|       3
---------------------------------------------------------------------------
  146-  168 (41.39/27.22)	MEALTVADTFEVQ..HNMQD..MIQQS
  423-  449 (31.61/19.27)	MPLTTLPDTLDLRgpYAMNDeeVIQSS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08316 with Med17 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ATFGNPDSLPRDNDGDDDGDDADEEMELDEVENVVVGMEDRKT
2) MPRQQASLKPMFGAGQQSSSNTQQPAGVNVALEA
69
1
111
34










Molecular Recognition Features






MoRF SequenceStartStop




1) MPRQQASLKPMFGAGQ
2) PDSLPR
1
74
16
79