<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08286

Description Uncharacterized protein
SequenceAPVVSAHTSRGIDFLERFGQFAKERALIEEEYAAKLKSLAKRSRGKKNEDDESKMYSTTMAFLTMLDEIESLASQHEVVGERLRNDLCPKLVEKCRQLRTMRKKQFQYFEMMEKHLQARVDELAKQKKNYEKAHLDAQGAHVKGAKADKNMNLSRIELEKAKTNANTKNAICEQSKQNYAAQLGATNQAKFEHYNVILPKVLEVMRQLDVERIEFSKKAMLECVAAETSVLNIIQRCYSDMNMAIGTINPNSDTLAVVEQTKTGFVHPLDFQFEDLGDPADILQDGTESFDGSTLKRQPGQGKGANGKGGGGVPRRRTLLISKFTNGSAGTHGGGSGGGTCGVNTGSEYGTLPPQQRCRKIQQKLEELEAELNIKDQSQAGMKRMHVAYTQNPQLGAPAKVAEQLLQNQQEMHTLQTQIQRFKELLQSAQGELNQPLGGNPHQHQAAQQQMYNATTTSLSSPGSSPRGSTGNVAGKLKNGQQHHRGGRFNGGGTQMGSAEQHRASSYSEVSSISSADGLVMSSASSFNSGSDASSTAARTTSGTIYAQLPPMSAHPQQHQQMNGINGGADGGVLHQSASGTTLSSNGAANCAPAVAPPNNTDSDDFYEECDTPAAAASNGCPVPQQQSDMVLGTASALYAYDATPDEVGGTTISMKDGDELSLLERDVGDGWTRVRHVHSNAEGFVPTSYLDCAMGVTWVFESQRSEKALELLFEQAGATLQGQPKSFKVDCLWYKPQSQIAAQISGFFVLHHSHFPDSSFIINANRSADGTAPSTAGRPSPVPPRATADRGFELQLDKFHNAGLVTDPTRYEVTGNEYRLKDFRIRVGTVATAGATVSVKGVVVEIEYAASNIVHQCRGLLEEIVEFFFGRPKVPEPDVFRRNSEQPDNYMAIDTLSQYLDIFSAIRKRSF
Length912
PositionHead
OrganismGlobodera pallida (Potato cyst nematode)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Tylenchomorpha> Tylenchoidea> Heteroderidae> Heteroderinae> Globodera.
Aromaticity0.06
Grand average of hydropathy-0.567
Instability index45.68
Isoelectric point6.45
Molecular weight99307.83
Publications









Function






Annotated function


GO - Cellular Component
cytoplasm	GO:0005737	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
plasma membrane	GO:0005886	IEA:UniProtKB-KW

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
endocytosis	GO:0006897	IEA:UniProtKB-KW
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
signal transduction	GO:0007165	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08286
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     717.29|     176|     181|     422|     601|       1
---------------------------------------------------------------------------
  249-  417 (182.79/96.79)	..................NPNSDTLA...VVEQTKTGFVHPLDFQFEDLGDPADILQDGtesfdgstlkRQPGQGKGANGkGG....GGVPRRRTlliSKFTN........G......SAGTHGGGSGGGTCGVNT..GSEYG.TLPPQQRCRKIQQKLEELE..AELNIKDQS...QAGmkrmhvaytqNP.QLGAPAK.VAEQLL......QNQqemhtlQT
  422-  601 (292.11/168.86)	FKELLQSAQGELNqplgGNPHQHQAAQQQMYNATTTSLSSPGSSPRGSTGNVAGKLKNG..........QQHHRGGRFNG.GG.TQMGSAEQHRA...SSYSEVSSISSADGL..VMSSASSFNSGSDASSTAARTTSGTIYA.QLPPMSAHPQQHQQMNGINGGADGGVLHQS...ASG..........TTLSSNGAAN.CAPAVA......PPN......NT
  607-  788 (242.38/132.16)	YEECDTPAAAASN....GCPVPQQ..QSDMVLGTASALYAYDATP.DEVGGTTISMKDG..........DELSLLERDVG.DGwTRVRHVHSN.A...EGFVPTSYLDCAMGVtwVFESQRSEKALELLFEQAGATLQGQPKSfKVDCLWYKPQS.QIAAQISGFF...VLHHShfpDSS..........FIINANRSADgTAPSTAgrpspvPPR......AT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.45|      17|      18|     113|     129|       2
---------------------------------------------------------------------------
  113-  129 (28.32/21.03)	EKHLQARVDEL..AKQKKN
  132-  150 (24.12/16.71)	KAHLDAQGAHVkgAKADKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.33|      14|     107|      85|      98|       3
---------------------------------------------------------------------------
   85-   98 (27.04/18.62)	NDLCPKLVEKCRQL
  195-  208 (24.29/16.05)	NVILPKVLEVMRQL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08286 with Med20 domain of Kingdom Metazoa
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