<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08259

Description Uncharacterized protein
SequenceMARNYWRGSHYLEWLLDRQDLMVHRIGDLKILGSEEEYQKVMIFFTEVIQAFGKSVEVRQQVVATATVYFKRFYSRNSLSSIDPWLMAPSCLFLASKVEVISIWSLFDFNHSNQEFGQLSQKNLITSCRNVVHNHYSAYFPDGYGYPYRPQDVLECEFILLEAMDCSLIVFHPYRPLVQFCEELRPQLPELADLLLERAWWIVNDSFRTDVCLHYPPYIIALGCLQTAFILLANNNDLLVGASASASLASASSRHVYITNHPQPSVNPLAVADHWFSELNVDMEKVLEVTRHLINLYELWRRFDEANEMPTLLLKKLPRPVVQPPPHVSQPYANPSNVPPGTIGGTGGGGVGSGASHSSASLSAGGGGGGGGAGPANHAAQVITATNSGSSGAASTGLPSDMQQQQQQTHLHHHPHAHPGQPVQRAGANTAGLRMHSQQQQQQQQQQQSQGMTHMVGLR
Length459
PositionKinase
OrganismEchinostoma caproni
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Trematoda> Digenea> Plagiorchiida> Echinostomata> Echinostomatoidea> Echinostomatidae> Echinostoma.
Aromaticity0.09
Grand average of hydropathy-0.254
Instability index51.92
Isoelectric point6.33
Molecular weight50898.92
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08259
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.47|      16|      19|     344|     362|       1
---------------------------------------------------------------------------
  355-  372 (25.64/16.49)	ASHSSASLsaGGGGGGG.G
  376-  392 (21.84/11.12)	ANHAAQVI..TATNSGSsG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.14|      23|      23|     412|     434|       2
---------------------------------------------------------------------------
  412-  434 (43.56/20.93)	HHHPHAHPGQPVQRAG.ANTAGLR
  436-  459 (36.58/16.60)	HSQQQQQQQQQQQSQGmTHMVGLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.05|      11|      24|     146|     157|       3
---------------------------------------------------------------------------
  146-  157 (20.02/15.83)	YPYRPQdVLECE
  172-  182 (25.03/14.63)	HPYRPL.VQFCE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.41|      12|      24|     275|     287|       6
---------------------------------------------------------------------------
  275-  287 (18.92/14.38)	W..FSELNvDMEKVL
  300-  313 (19.49/10.14)	WrrFDEAN.EMPTLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08259 with CycC domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LKKLPRPVVQPPPHVSQPYANPSNVPPGTIGGTGGGGVGSGASHSSASLSAGGGGGGGGAGPANHAAQVITATNSGSSGAASTGLPSDMQQQQQQTHLHHHPHAHPGQPVQRAGANTAGLRMHSQQQQQQQQQQQSQGMTHMVGLR
314
459










Molecular Recognition Features






MoRF SequenceStartStop




NANANA