<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08251

Description Uncharacterized protein
SequenceMSAELRIVKLFEEVLEDKNIVPSFDEEEQRKKTEEGYKKIGTLFGAMTPEVKEASIRSYLGYVATVNHQNRVHNYLQVMNRMVALNIIPAKLLCDQLMCSEKLVYKNPCFWIEAFRLIRKVIGGVDYKGVREIMKCCKEKALSFPANVSVNILPQLLELIELIEHIFNRNACLLPAYFIINEIKKTDYQNMHWRVSNLTANFIEEFVSVAQMLSIIGHSSMLPIVEHSSYADNLIIPWKLDPDTLKLSLRGNLPYDEELLQPQARLLRFVLQQPYSRDMVCSMLNFQKQQKQKCAALEEQLVWLVLNAMEYSEKEGAQGQGAAGAAMGNEHDNDQSHTQWVWLHLSSQLIYFVLFQFATFQNIVNALHEKLAVRNLRRGRDHLMWVFLQYISGSIQKHSILNFLPILKLYDILYPEKEPLPVPDNNNPNCTHQMAPTCIWIHLMKRAQTENYNINRPIPIALRLHFEYLQHLAMPSNNPTLFMGSEYRFALLCNAYSTQTDYFSRPMQALIDTILGNSKNPQANMVGGGGVQPLPTAPLSMRVLDSLTIHSKMSLIHSIVMHMIKQAQNKSSIPNGNNMAPALVETYSRLLVYTEIESLGIKGFLGQLLPQVFKSQAWGILYTLLEMFSYRMHHIHSHYRVQLLTHLHSLASVPHTNQMQLHSCVESTALRLIIGLGSVEVQAQLSRYLSEPKPPGNIVSAESEELNRALILTLARSMHITGTGSDPQSSAWCKDLLQNIMLNTPHAWPQHTLYCFPPVLNEFFMQHNIPKESKQLLKKTVDEEYRNWASMTNENDIIAHFGMTVNPPLFLCLVFKMIIETDGISPVAYKILERIGARALSTHLRKMCDYLLFEVANSGGGAHVNKCVDTINDMIWKYNIVTIDRLVLCLILRTLDGNEAQVSFYIIQLLLLKTSEFRNRVQEFITINSPEHWKQNNWHERHLAFHQKFPEKFAPDESVSHPTLPVYFGNVCLRFLPVLDIIVHRFLEVPTQLSKTLDVILDHLGSLYKFHDRPITYLYNTLHYYERKLRDRPQLKKRLVGTVVGSLKDVRPENWALTEAYQAYVLTKETDNVNWVPELTYYINLVRRMQDTMDGKNVFSGTDWRFNEFPNPPAHALYVTCVELLGLPVGPNVVANSIIDVLVKGYTVVPNAVIHNWANTIGLIMSALPEAYWSVIYERMQGALGSKSMKDWAYRQSPFEMFNFKIVKESMLDRSYVTVLAIVHSIFHHFGIGQLATITESIKEKLKPLVHTEYQLIYVCHVVGPFLHRLSIERARAVSDITLMLYELLEQVDKAQPTQPLRYMDPICDLLYHIKYMFVGDTMKTELEAIIRRLRPALQMRLRFITRLNVEEIGVDQTAAGGQGNAAAATAAGSATGASLAPGAASGTASGTPQGLAVAAGQGAAGSGTGGSQQTQQVGAVGNQNVALQQQLQQQLGQQGIQSHH
Length1445
PositionTail
OrganismAnopheles stephensi (Indo-Pakistan malaria mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.09
Grand average of hydropathy-0.101
Instability index43.50
Isoelectric point7.63
Molecular weight164123.01
Publications
PubMed=25244985

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08251
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     147.31|      45|     147|      87|     136|       1
---------------------------------------------------------------------------
   87-  136 (68.15/60.17)	IIPAKLLCDQLMCSEK..LVYKNPCFWIEAfRLIRKVIGGvDYKgvREiMKC
  235-  281 (79.16/48.67)	IIPWKLDPDTLKLSLRgnLPYDEELLQPQA.RLLRFVLQQ.PYS..RD.MVC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.04|      36|      74|     795|     833|       2
---------------------------------------------------------------------------
  795-  833 (59.74/41.24)	NDIIAHFGMTVNPPLFLCLVFKMIietDGI.SPVAYKILE
  872-  908 (59.30/33.95)	NDMIWKYNIVTIDRLVLCLILRTL...DGNeAQVSFYIIQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     200.51|      67|    1081|       5|      85|       3
---------------------------------------------------------------------------
    5-   74 (102.29/106.49)	LRIVKLFEEVLeDKN..IVPSFDEEEQRKKTEegYKKIGTLFGAMTPE.....VKEASIRSYLGY...VATVNHQNRVHN
  157-  233 (98.22/66.62)	LELIELIEHIF.NRNacLLPAYFIINEIKKTD..YQNMHWRVSNLTANfieefVSVAQMLSIIGHssmLPIVEHSSYADN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     167.76|      51|     326|     957|    1018|       4
---------------------------------------------------------------------------
  961- 1018 (83.66/63.08)	HPTLPvyfgnvcLRFL.PVLDIIVH.RFLEVPTQLSKTLDVILDHLGSLYKFHDRPITYL
 1296- 1348 (84.10/42.14)	QPTQP.......LRYMdPICDLLYHiKYMFVGDTMKTELEAIIRRLRPALQMRLRFITRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.67|      15|      15|    1403|    1417|       5
---------------------------------------------------------------------------
 1403- 1417 (29.35/21.37)	GAAGSGTGGSQQ..TQQ
 1419- 1435 (21.32/13.25)	GAVGNQNVALQQqlQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.39|      19|      90|    1077|    1096|       9
---------------------------------------------------------------------------
 1077- 1096 (31.51/22.92)	PElTYYINLVRRMQDTMDGK
 1169- 1187 (35.88/21.67)	PE.AYWSVIYERMQGALGSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.87|      31|      48|     426|     458|      12
---------------------------------------------------------------------------
  426-  458 (55.04/39.58)	NNPncTHQMAPTCIWIHLMKRAQTENYNINRPI
  477-  507 (57.83/34.45)	NNP..TLFMGSEYRFALLCNAYSTQTDYFSRPM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     158.00|      47|     612|     612|     680|      13
---------------------------------------------------------------------------
  618-  667 (79.44/71.98)	WGILYTLLEMFSYRMHH...IHSHYrVQLLTHLHSLasVPHTNQMQLHSCVES
 1192- 1241 (78.57/32.60)	WAYRQSPFEMFNFKIVKesmLDRSY.VTVLAIVHSI..FHHFGIGQLATITES
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08251 with Med23 domain of Kingdom Metazoa
Unable to open file!