<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08241

Description Uncharacterized protein
SequenceMMNPNHSGASRRPYSRGAVPRNRSRMPFSPHHTHHANRNHGGHNQSWYNKDMENSFNYGAGPSHIDRHRINMGGNSMQDRNRHTMSASSIDRHSNHFEGPSNSTRGSDLHGGGDARSVLSMDSMRNSRDNNGGARERFSPHYHSGPGGNGSGPAGGGGGGGGGGPNQSSSPPYCPVDGIGGNGGIKSDSPSRKRRRVSSRLPSQSPPAAIWEHRRSPRNGGGGGGGGGGMMSLMGTSGGSANGGGGNGGLGNHAMNGHHNLSLQQQQPQSSQSMQQQQQQQQQQPQLLHRDHPQQQQHHHHQLHHHHHHSQQQQQQQQSHHHSNGGAGSHLHPSSGGNLAAAIISQLQSHVHHPQGSPPIRRPRFHREQQQQQQQQPQQQQQQQQPQQQQRPWESLTQVFQQAPAAQAQHQHPASSLMVDINQVPVSLPLGHHHEQLWTYSAGPHISICSGHPAAPHLPPCQVHGVYSQPFAQTCGIGGHFGSFASSAGPALAVPHPPPHQAHYQHPHLAQQRTDGISLDGLEHAGASPLHLSPLTTHAHHLHGASPQMTQLTAAAQPIYISTEVSAVGSEVPRTGVTPAGTLIPLIANVPQGRNYEILHRTVRRAITAPRRNFARFHWPGPPPPPPPPPPPAHHQHHHPGHHHPTHHHRPHAPPPPPPAALQAHPQPLGHPQPAHVTLSATTSAYSGILLNFLAMFPLSTYGPPDLNSPDSNETENYEALLSLAERLGEAKPRGLARPEIDQLPSYKFNAETHTGDQTSCVVCMCDFEARQILRVLPCSHEFHAKCVDKWLRSNRTCPICRGNASEYFESSEEQ
Length815
PositionKinase
OrganismAnopheles stephensi (Indo-Pakistan malaria mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.05
Grand average of hydropathy-0.954
Instability index69.61
Isoelectric point9.37
Molecular weight88407.17
Publications
PubMed=25244985

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
metal ion binding	GO:0046872	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08241
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     152.78|      30|      30|     618|     647|       1
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  370-  410 (37.89/ 6.57)	QQQQQQQPQQQQQQQQPQQQQRPwesltqvfqqaPAAQAQH
  608-  637 (56.74/14.16)	TAPRRNFARFHWPGPPPPPPPPP...........PPAHHQH
  638-  665 (58.15/14.72)	HHPGHHHPTHH..HRPHAPPPPP...........PAALQAH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     144.04|      27|      30|     264|     290|       2
---------------------------------------------------------------------------
  264-  287 (36.81/ 8.19)	.........QQQQPQS.........SQ..SMQQQQQQQQQQPQL
  288-  319 (41.91/10.45)	LHR...dhpQQQQHHH.........HQlhHHHHHSQQQQQQQQS
  320-  360 (32.64/ 6.33)	HHHsnggagSHLHPSSggnlaaaiiSQ...LQSHVHHPQGSPPI
  496-  516 (32.68/ 6.36)	............HPPP.........HQ..AHYQHPHLAQQRTDG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     250.02|      55|      62|     129|     185|       3
---------------------------------------------------------------------------
    5-   76 (44.06/10.72)	.NH.....SGASRRpysrgavprnrsrmpFS...PH.HT...............HHANRN..HGGHNQSwynkdmeNSFNYgaGPshIDrhriNMGGN..S
   79-  127 (53.25/14.15)	DRNrhtmsASSIDR...............HS...NHFE............GPSNSTRGSDlhGGGDARS.......V......LS..MD....SMRNS...
  129-  185 (110.38/41.62)	DNN.....GGARER...............FS...PHYHSGPGG....NGSGPAGGGGGGG..GGGPNQS.......SSPPY..CP..VD....GIGGNggI
  188-  229 (42.34/ 9.69)	DSP.....SRKRRR...............VSsrlPS.QSPPAAiwehRRSPRNGGGGGGG..GGG....................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.57|      28|      31|     680|     710|       4
---------------------------------------------------------------------------
  680-  710 (37.54/37.38)	SATTSAYSGiLLNfLAMfPLSTYGPPDLNSP
  712-  739 (48.03/30.22)	SNETENYEA.LLS.LAE.RLGEAKPRGLARP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.22|      18|      23|     547|     565|      10
---------------------------------------------------------------------------
  550-  574 (24.43/11.95)	TQLTAAAQPIYISTEVsavgsevPR
  575-  592 (29.80/11.03)	TGVTPAGTLIPLIANV.......PQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.04|      21|      36|     744|     764|      11
---------------------------------------------------------------------------
  744-  764 (40.00/21.82)	LP.SYKFNA...ETHTGDQTSCVVC
  777-  801 (33.04/16.86)	LPcSHEFHAkcvDKWLRSNRTCPIC
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08241 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MMNPNHSGASRRPYSRGAVPRNRSRMPFSPHHTHHANRNHGGHNQSWYNKDMENSFNYGAGPSHIDRHRINMGGNSMQDRNRHTMSASSIDRHSNHFEGPSNSTRGSDLHGGGDARSVLSMDSMRNSRDNNGGARERFSPHYHSGPGGNGSGPAGGGGGGGGGGPNQSSSPPYCPVDGIGGNGGIKSDSPSRKRRRVSSRLPSQSPPAAIWEHRRSPRNGGGGGGGGGGMMSLMGTSGGSANGGGGNGGLGNHAMNGHHNLSLQQQQPQSSQSMQQQQQQQQQQPQLLHRDHPQQQQHHHHQLHHHHHHSQQQQQQQQSHHHSNGGAGSHLHPSSGGNLAAAIISQLQSHVHHPQGSPPIRRPRFHREQQQQQQQQPQQQQQQQQPQQQQRPWESLTQVFQQAPAAQAQHQHPASSLMVDINQVPV
2) PPDLNSPDSNETENYEALLSLAERLGEAKPRGLA
3) PRRNFARFHWPGPPPPPPPPPPPAHHQHHHPGHHHPTHHHRPHAPPPPPPAALQAHPQPLGHPQPAHVTLSA
4) SAGPALAVPHPPPHQAHYQHPHLAQQRTDGISLDGLE
5) SPLHLSPLTTHAHHLHGASPQMTQLTAAAQP
1
704
610
487
528
426
737
681
523
558










Molecular Recognition Features






MoRF SequenceStartStop




NANANA