<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08238

Description XK-related protein
SequenceMTEFLPLCDVLFNVISLAGYFCDVVFDVVLGYALYERQKFAYFAAVIVIVSFSLVISQIVSIRWYLNKRKIRNATASTTGPPGLQDAEAAANAPGSTSGSLEKKKKKPNSLTTANGPGACIGARTDDTDERPSNGGSRSSEYSRYIVLALHFTQLGVLWRYAKLFVPVDLRHVKHEVRDLCMLRLVHAFCEAAPMLLLQLYVLVTLQSEAQLAATLKLKTLGHHHHLPASTALVQQTNLAEQQQKTFRDLNMVSATLSLFSVCWALASFSKNVRLQNVHRLVLTWLGVIFQFLWRLGTVISRVISLTVYASVYSHWVFLVIILHWFSMFLWLISPKNVFHGERISRLKKTTLGGLIAFVYIFAYINLQEVRHRQKMLTFYVVMFAENCLLVCLWMVGVWPNRPEGWYLVPVSVLCSFAAGLFFMVVYYRYFHVRRLGYEAGGRISEKCSGHCGTDGCRCLTGHENGIDGVGINGGGGCKVGGGIGGGLGGGGLHGGGGQKYPHAIPGVFNCRFSNPVNAATKRKKKKPTTFVPPPNLAIASQNSAGAGAAANDHQNVTSQFLQHQAHQPQQQHAQQQQQQQLQQRQQQHHQQQQQQYLQQQPLISHQEQQQQAQQQFQQQQQQQQQQQQYMGPMAIPFWRRPLPRSHTGGSSENEGSSVGSRVNIQQKLQEKKQKQLAELKIIEEEIKQGKLGGPGGTGTLSSGDDGKTTLPRQPIPRAKKHIDLDPIEWRTSSPDMAEIVANKSFNDLNLLLAANLDDVNSLNKFNSNYDPIYNSFGLNGINISALVNLKGVAGGTGSLVDTGGQSASVPVVGPVVGPGNRNMSPISSQISATESNSLTRQVMPRSKILPNNIPRNPFAENYRGNFVNLYADAAASTPTGLINGAANGNGNGGGSGVRAPSISPRTTEIAQSNRAILYDAHGRLYTDANHPRQVSGTYSSTENAGAENLPFPYNVVPPPRSKLDSRGTPTTPVQSGSASGSANNTNSSNKSGRTATTATMAAIVASVGGAGGSSSGAVGAGGVGAAGVINNLNNTKRQNMQRAKTPEILLAPHYLENSRIYFDWVAREAANFRLQESERDQPMESSGDENLDNSGCDDGHNGHHRIPSDIDSQVSLPRSYTLPREFKYYRRNKGRKVKNEHFIASTNSSDGDVDSGDDNESERLSNLSSSSQRRVKNATPCTNLTNGHHAPALQQQQHPQQPLPRQRMNNLNKGVAQNQPSISASMALMYAGGSGGQSPSGTMLHANGQAIPPVNTCRQTLNATPQNLHQPPLPQHAAVALSNGYNLTGGGDRSSPAMPALLSGNDGSPVGLPGKPGAVHSFDLISGVEAVGAALPPYHAGGAGGGGGGGAGNGGGVARPTRFRMYGTKNGMANQEDTSQQSGLATVESEYDTASDSPSDGGEEEDEEEDYEDEESGGEEEEEDDEDDDGSDGTDDDGTEEEEDEDDVIEVLERQSGDGQEQDSESRRKVDDDEDRSNPQYIPKKGTFYEHDDRTAEDDLDDSGLDGDEQRSKRNDDGLGDGMGDSHGGGGGGPGSGGGGGGGGLGAPGMYGGERRGSEKGGSGPGAKGTKKWQASTDRWTHDRFDESEQAPKSQAELVFAYGYDIRSEDGPPKARRKRRYARGPNRYTRNWEDEDAYQKSSNAEHHQRHKKVPRPEEFPELGGANGKSGRATGRGRNGQKSGSSVAGGPDQRRQSGATDGGRTRSSDVRRSGGQDRSMGRSERVRSGDWGSAAGGDRERDSDRGADWDRSEYGGSGGGSLRYRNEDRGSRNNYHNKENKLSGARNSKEKDYKVINSLQFKNQARNKNMEGGPGGNGGASVAGPMPGSGASSGLPDGNPGAAPMMHSNSAGALSGSSNSNKMNNHGTVQQQHNSSNSPNAGGVANDRIHHVEQNQQQGRMMNVVTTSASLGSVPSSGAQQHYGHHASSMGQMQQQQHSNQQQMQQPQPQQPTQKLKQGYLEEDHSKYAVPLYAGSSAMDRMPPNVASGAGAPAVGNLPMNQRSQISPRAIVAQTPPSAPSEQVSSDRMAVQMEYQSMQGAGVPQGYGGQQRSLAVQQQQQQQVSNQMQHQQQQPMLQTEVPRNTKRYSTQRQRSAMESAANASALQAQQQQQQQQAAAAAAAAAASMHEQQQMLQHQQLLRHQHEQLAQQSKQKQVYSQQQLPPAGPTPGGLPMTLQAADYHGAVNKAPPPAQGAPGGQNPAQVQYHQPTAIYYTSAGGAGGPPPGEYVTAAAPGGQPQQQPPQPPTQAPPPPQAQYAPPPYATQGPPPQPPQAASYLQGPVSAPSAYLPAPQPASVPTVPQPPSGVPGGAPPPPMNFVPALGPPPTAPAPGVSPGQYSGPGAYTTGFQTGYAPAIGVVPQAVPGGPPPPPVVAGPPTGGPGGPPPTALYQSSGGITYYAPQTQTQAPRPLPTGRRPTAAIPILAPPDRKPAGGSTAASAGANKTSSSTRPAAGESNEAADVGTGVASNAEASGGPGTTVDSGENIDHILDNMFVQRPQYQPPSRKSPSPALAPTATGQQQPQQPQQGSLPPGTETANGAAELRSESGSTGASDGQESMDNIGESVKNMSIQDTDKLSLASGSLTVEGKEAAAGIIETSAPAQPVE
Length2607
PositionTail
OrganismAnopheles stephensi (Indo-Pakistan malaria mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.06
Grand average of hydropathy-0.719
Instability index60.48
Isoelectric point6.96
Molecular weight277021.19
Publications
PubMed=25244985

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IEA:UniProtKB-SubCell
integral component of membrane	GO:0016021	IEA:UniProtKB-UniRule
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
RNA binding	GO:0003723	IEA:UniProtKB-KW

GO - Biological Process
mRNA processing	GO:0006397	IEA:UniProtKB-KW
mRNA transport	GO:0051028	IEA:UniProtKB-KW
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	GO:0000184	IEA:UniProtKB-KW
regulation of translation	GO:0006417	IEA:UniProtKB-KW
RNA splicing	GO:0008380	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08238
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     175.80|      32|      34|    2293|    2324|       1
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 2203- 2239 (33.77/ 7.74)	AQVqyhqPTaIYYTSAGGAGG..PPPGEYVT....AAApgGQP
 2240- 2272 (43.74/12.61)	QQQ....P...PQPPTQAP...PPPQAQYAPppyaTQGppPQP
 2273- 2295 (31.29/ 6.53)	PQA....AS.YLQGPVSAPSAYLPAP...............QP
 2296- 2327 (67.01/23.99)	ASV....PT.VPQPPSGVPGGAPPPPMNFVP....ALG..PPP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     144.48|      33|      34|    1389|    1421|       2
---------------------------------------------------------------------------
 1330- 1381 (30.58/ 6.68)	EAV.GAA....LPPYHAGGAGGGGG....GGAG.NgggvarptrfrmygtkngmaNQED...T..SQ
 1382- 1415 (41.07/11.80)	QSGlATV....ESEYDTASDSPSDG....GEEE.D....................EEED..YE..DE
 1416- 1455 (30.00/ 6.40)	ESG.GEE....EEE.DDEDDDGSDGtdddGTEE.E....................EDEDdvIEvlER
 1518- 1555 (42.82/12.65)	DGL.GDGmgdsHGGGGGGPGSGGGG....GGGGlG....................APGM..YG..GE
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     238.70|      32|      34|     567|     598|       3
---------------------------------------------------------------------------
  552-  587 (51.07/19.88)	NDHQN.............V..........TSQFLqhqaHQPQQQH.....AQQQQQ..QQLQQRQ.Q
  588-  622 (54.80/21.92)	QHHQQ.............Q..........QQQYL...qQQPLISH.....QEQQQQaqQQFQQQQ.Q
 1924- 1950 (38.13/12.78)	GHHAS.............S..........MGQMQ....QQ...QH........SNQ..QQMQQPQpQ
 2042- 2068 (35.08/11.10)	...G..............V..........PQGYG....GQQR.SL.....AVQQQQ..QQQVSNQ.M
 2069- 2111 (28.61/ 7.55)	QHQQQ.............QpmlqtevprnTKRYS....TQRQRSA.....MESAAN.aSALQAQQ.Q
 2112- 2162 (31.00/ 8.86)	QQQQQaaaaaaaaaasmhE..........QQQML...qHQQLLRHqheqlAQQSKQ..KQVYSQQ.Q
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.07|      16|      16|    1692|    1707|       4
---------------------------------------------------------------------------
 1356- 1371 (24.16/ 8.48)	GGVARPTRFRMYGTKN
 1702- 1717 (24.91/ 9.01)	GGRTRSSDVRRSGGQD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     270.39|      45|      45|    2333|    2377|       5
---------------------------------------------------------------------------
  955- 1017 (48.20/12.39)	NVVPP..............P.....RSKL.DSR..GTPtTP.V.QSGSASGSANntnssnksgrtattA...........TmaaIV.ASVGGAGGSSSG
 2333- 2371 (64.73/19.23)	.........................GVSP.GQY..SGP.GA.Y.TTGFQTGYAP..............A...........I...GV.VPQAVPGGPPPP
 2372- 2419 (53.04/14.39)	PVVAG..............PptggpGGPP........P.TAlYqSSGGITYYAP..............Q...........T...QTqAPRPLPTGRRPT
 2423- 2479 (48.87/12.67)	PILAP..............P.....DRKPaGGStaASA.GA.N.KTSSSTR..P..............AagesneaadvgT...GV.ASNAEASGGPGT
 2480- 2533 (55.55/15.43)	TVDSGenidhildnmfvqrP.....QYQP.PSR..KSP.SP.A.LAPTATGQQQ..................................PQQPQQGSLPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.49|      15|      15|    1974|    1988|       6
---------------------------------------------------------------------------
 1974- 1988 (28.91/12.41)	AGSSAMDRMPPNVAS
 1990- 2004 (22.58/ 7.88)	AGAPAVGNLPMNQRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.77|      32|      35|    1798|    1830|       7
---------------------------------------------------------------------------
 1798- 1830 (53.77/24.17)	SLQFKNQARNKNMEGGPGGN...................GGASVaGPMPGSG
 1868- 1918 (37.00/11.65)	TVQQQHNSSNSPNAGGVANDrihhveqnqqqgrmmnvvtTSASL.GSVPSSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     130.68|      28|      46|    1672|    1699|       9
---------------------------------------------------------------------------
 1580- 1623 (26.25/ 6.89)	RW.....THD....rfDESEQAPksqaelvfAYGYDIRSEDGP............pkarrkRRYA
 1624- 1659 (29.40/ 8.69)	RGpnrytRNWededayQKSSNA...........EHHQRHKKVP..................RPEE
 1676- 1721 (37.77/13.47)	RG.....RNG......QKSGSSV........AGGPDQRRQSGAtdggrtrssdvrrsggqdRSMG
 1745- 1768 (37.26/13.18)	RG.....ADW......DRSEYGG........SGGGSLR......................yRNED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.46|      19|      20|     466|     484|      10
---------------------------------------------------------------------------
  466-  484 (37.33/14.36)	GIDGVGINGGGGCKVGGGI
  487-  505 (37.13/14.24)	GLGGGGLHGGGGQKYPHAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.92|      15|      15|    1201|    1215|      11
---------------------------------------------------------------------------
 1201- 1215 (27.15/12.82)	QQPLPRQRMNNLNKG
 1219- 1233 (21.30/ 8.20)	NQPSISASMALMYAG
 1271- 1285 (23.46/ 9.91)	QPPLPQHAAVALSNG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.57|      12|      15|     798|     809|      12
---------------------------------------------------------------------------
  798-  809 (20.33/ 8.70)	GSLVDTGGQSAS
  814-  825 (23.24/11.22)	GPVVGPGNRNMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.66|      14|      16|    1832|    1845|      14
---------------------------------------------------------------------------
 1832- 1845 (26.36/10.64)	SSGLPDGNPGAAPM
 1850- 1863 (23.30/ 8.51)	SAGALSGSSNSNKM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.01|      17|      34|    1459|    1478|      15
---------------------------------------------------------------------------
 1459- 1478 (26.41/24.94)	DGQEQDSesrRKVDDDEDRS
 1488- 1504 (30.60/19.54)	TFYEHDD...RTAEDDLDDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.25|      15|      35|    1136|    1152|      16
---------------------------------------------------------------------------
 1136- 1152 (21.88/19.16)	RKVKNEHfiASTNSSDG
 1174- 1188 (28.37/17.15)	RRVKNAT..PCTNLTNG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.58|      33|      42|     643|     684|      18
---------------------------------------------------------------------------
  624-  660 (50.12/37.21)	QQQQQQYMGPMAIpfWRrpLPRSHTGGSSENEGSSVG
  670-  704 (48.46/19.75)	QEKKQKQLAELKI..IEeeIKQGKLGGPGGTGTLSSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.86|      15|     340|     713|     727|      19
---------------------------------------------------------------------------
  713-  727 (29.31/19.98)	RQPIPRAK.KHIDLDP
 1038- 1053 (23.55/14.31)	RQNMQRAKtPEILLAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.78|      41|      53|     851|     894|      20
---------------------------------------------------------------------------
  851-  894 (66.23/48.81)	PNNIPRN.PFAENYRGNFVN....LYADaaASTPTgLINGAANGNGNGG
  901-  946 (62.55/35.86)	PSISPRTtEIAQSNRAILYDahgrLYTD..ANHPR.QVSGTYSSTENAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.98|      17|      35|    2548|    2565|      21
---------------------------------------------------------------------------
 2548- 2565 (26.02/18.03)	SGSTgASDGQESMDNIGE
 2582- 2598 (27.96/14.25)	SGSL.TVEGKEAAAGIIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.04|      35|      35|     165|     199|      25
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  165-  199 (60.84/44.82)	FVPVDLRHVKHEVRDLCMLRLVHAFCEAAPMLLLQ
  201-  235 (56.19/40.78)	YVLVTLQSEAQLAATLKLKTLGHHHHLPASTALVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.20|      15|      20|    1291|    1305|      26
---------------------------------------------------------------------------
 1291- 1305 (27.92/14.50)	GGDRSSPAMPA......LLSG
 1308- 1328 (22.28/ 9.54)	GSPVGLPGKPGavhsfdLISG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08238 with Med15 domain of Kingdom Metazoa
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