<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08227

Description Uncharacterized protein
SequenceMIMDNSKTTSKTTLLKLMLLRAWKERWTDCQWGINVKTILTRGVSGDVYNLADAIVQQAVVGSGANMLFLSYLKHSLCAHLISHAAVLNRIAKYDQFDKHHCLIALLDFLKSIIDGVTCRGKQEESILTKATVALVHWLLQIYECILKAYADSRALQTEEEDVVQRVAIVLERIVENPFLLGVLSIGKCEDPDLFLTLQKRFNGINNLTITTGYVAHVGSSPKNVTVTDYMRKLVLLEVDILEMKQFDGGKVEPITFSLQPFIAIEVLLNPMTDTNQNVAQLITLKRLKGYSYARLYCEIMRGCLISLNNVEGTSKESLLCAFAFIKVPHILHQIHTKTNGKEQQDEATSANYSVDLVEAFELLLQDAPVLDYMDMKCSCNIVECLLKEMVKHHLLTETHVKHFVALRDPVTVGLHKLEANNAHLTLMLKFVFRVESPLVGILKALSADYSKVQDALLAMLCQVLTGNSLDLIVSVASVEGKFKTFIAGLLKCNDYAKQTTSVEIGKASTTRGALFDVTFMILACIAQSYGSDVILAEGGNSFFEKWVRDYMVERKKSKSPMTMVKQADPMVLEELIMALNSSNDGGGGLKGSNLRWEDICYTIPALLHQVLMAWENEKISPVEIKKMLDGLKAHFCSFAVCASSWLCAYMQMVRQDEQVKPMNMVQQLCSVLAGPQAEEWQQQDYCKERFGLMGQIIRRMQQEFQRTPQINPKLRALFPSQHMVSHLPLEEQFEEAWKAIVERGWLPIETTFLLDTLLQSCGPSWLVEKLIAKLFLCKYIRDLNKTMDIVFAIMHLDVERCTIALLSQLVPMMLQNKQQTPEIVDPQSRVLAKLCVYCIIVTMEASITASKKRTRATVGSELEDIDSLCTSAKLRKIELDGMGVGCEATGGNDFALESALDSVASWDGASVPSLKEPLQGCLQTLFRTFTQYITTDELSPKVYFIFQFLSLLVESGRDRIACVLKLLPNGLYDLNTPTGRQCAMSDVCLLRNIQMRKESIKL
Length1003
PositionTail
OrganismAnopheles stephensi (Indo-Pakistan malaria mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.07
Grand average of hydropathy0.085
Instability index39.73
Isoelectric point6.35
Molecular weight112616.47
Publications
PubMed=25244985

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP08227
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.05|      40|     231|     504|     574|       1
---------------------------------------------------------------------------
  504-  551 (55.57/49.57)	EIGKA.STTRGA.LFDVTFMiLACIAQSYGSDVILAeggnsffEKWVRDY
  610-  650 (64.05/64.72)	QVLMAwENEKIS.PVEIKKM.LDGLKAHFCSFAVCA.......SSWLCAY
  739-  767 (37.43/15.16)	...KA.IVERGWlPIETTFL.LDTLLQSCGP.............SWL...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.23|      30|     112|     687|     718|       6
---------------------------------------------------------------------------
  687-  718 (51.43/44.40)	CKerFGLMGQIIRRMQQEFQRTPQI.NPKLRAL
  802-  832 (49.80/35.72)	CT..IALLSQLVPMMLQNKQQTPEIvDPQSRVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.86|      31|     303|     156|     191|       7
---------------------------------------------------------------------------
  156-  191 (42.08/39.03)	LQTEEEDVVQRVAIVLERIveNPFLLGVLsigKCED
  465-  495 (51.78/32.29)	LTGNSLDLIVSVASVEGKF..KTFIAGLL...KCND
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP08227 with Med24 domain of Kingdom Metazoa

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