<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08222

Description Uncharacterized protein
SequenceMPKILDTDIDSPIANLIKRSGTGNSTTTTNHSSSGSSKQSAHYSNDTTSEKSDGPYEALVGRHHIVSGGGGNSNSSSSFFSSAYDAKDGSNEGGSSYGSGQLAGGGLGGGVGSLTQTLPPPPQQGQSAFFQSTNSITSHQQQTRGHRSGPDGVPPDGGKGTGNAPETRVKKYRHQQFSKNIYIGTKNAEKWDTLRNVLLFKNDVEFVSFLLKLAESNCWKKDSPLLNGFHSETVPLKPQAASTKGVRTKSGTRGKQQQQQQEHPPDGQQQQLEQHPHQQPLHTSSISFTSSKAAGSIGKKTKRVQFNKNVNIIHKLDNRRTGKMVSFSDKALADEPSNPSHREEDSTAVPEMDEDGGMEDDEDEDQEEEDEEEEEEDEEGEEMEEEDGEEEEDEEEEDEEEEERGEEKEAMTGKADDGAVPVEHADVVLRKADGFLGDCKEQESTGHDAYLMEDIVKKTMRKTLPPPPANPQPQQSNEVQQDSISSTMGSVSEDSLNTETEVLDYRIAEKIKTELEEKQKLERKTHTAEELPTTSNFFDQCDFDPGSVDEKPATLPLVKKGALDRTRSGTSLEQSVYSGGGGGGGGGGGRKRGRRANAAHDSGNVDLHIEYEEQEYRPLPGSRASDGGLLEKSNFTPKQLHHTPTAPRKAKGVGTAKHKVCAGCNVKHGADQCPLSTPLRAISNKIELNQWLEQNEDLIKKHKLFLKPTGNGEDMDDEMDDQYDDDEDDEDDDVDDEDDDGGEGSRGNGKIELSPSFSEVSVPPEFELRLCPQSSANASAITSTTQSEALQQQELQTTGKLNQLPPDVAPQHQEQQDQDSIMESKGSVPPSSSSSSSFVGTLGTERDPAPKSRPVSGHGLSIYTTTFIAKYTKIGPLTGQIVRETEIQDDCTMRHIFETFDGVKSTYTSTENKNFSNWLRYIRPARNREQKNCVLQVHDGGIYFVTSKDLEPGTELLYWSNDSNSAWGKKKMEKTNCGGCNLKFDHPFYYRTHCSVFHDPGFSLTIRKYHCKVCGAAVLGKENIMKHAEKLHDGKGAYQCQFCQKFFLRLNYLEMHRTYGCSANPQRTRPLCDFCGRKFCQPQKLKVHIKRMHSDMADVLRDFQCKLCSKLLGSRAALQRHSKEVHSRNSAVVSCPRCQKLFQNRSNLKIHMLTHSGVRPFKCAENECTAAFTTKQCLQFHYKKVHGYTQEQMPKIERSVAYTFDAYSGGLNDGIIDEVQRRQRHKSSASEEGGYPSEKVERKKRSRHLNHFDETSLHQQHQAQLQPPLQQQQQQQQQQQQSDLAQGLGQESNDPSKAPSQHLQQQSPPHPQLDYPNTPPASQHLSTHPSTAQQQLQLGSVLPNADVLQKDAELHQQKLLRQQQQQHAQQLAVHQADDQQDTVDQATGSQMQHHQHDLHSDPQHSSLDDQVMAKADQEEQSMHHHHHHHQQLARLPSPFSNNLLKTKNILESFNDLCRNESNLSLLSTKISSILNNNLKDIAKVAAIGTSAGSNGGNVEDIRKNIIDHQGLEEGRSDRLDDMQHLVHPLPDDQSKANSLNVSQLHRLNISNQLDTGTAAALQYKTSSDDDMKSVAEVDNNFVDMASLASNLKYKEYINGGGNAGLVISKGSKKWISDTDQLPGVDGQQGEPGVMLSTVSGRDFLTKLIMNGNVNTPPPNVADDEEEDDDNSTILDVVDSNNPNQQSTHAQIQQYTSNFTGLNLPDLPSFQSHAFQGHFNHQTLLGSFYNNSGTGTGRNTINTIPTSASMLVEAALNSVSNIITEAEISTNNNGGTNSNNQNQGLNINHIDPGSGTDTASNNNVSANSFNASNIDESVDDMKLLKSHHFSMQLNSISQYSAQSTNDSGILSIRGAGSGAASRPKSREKIAIYEDSEMLNYENQHLSQQLQGTPHKLTSSVDSVRSALSPEQTGDFSYAATPSTSSRQHIVSGSPVRSSSRQIYAEHDLISPASTPSLPRYDFGPTDSSNYGSSRRQDAKTISSLTLESFESNLKDTAHHMQQLSSDEDNSIVIAENLSVNAVSTEEKLKLSNAATATNANNNAPSGGGTSATEFIQHQKYGETGRTIGGSNLSTTADMRIKYGNDELVDFQQRNNIGDASDFQGLDMSSRSSVSAYHHTNFQLSTQAGSNLHFNRYHHHIYDILSEREQQQQQPQQQQQQQQQQQQQQQSQQQQHHHQQQQQQQQQQQHHQHQHQHHHHQHQSQQQQQQQQQQQQQQQSQQHSQQQQQQQQQESFQLEQTQLQHLVQEHVQNQDSDADQSVTVDLSRSSSYLVQSPPTPAISYSSHHHPDMIRMVSLDLSSNTGSHHAVNNGSHHAVRHASFISSQIQPAEHHRLLAGDQLSASNHRLLVSDPATHLIFEQNNRLLSDATGQPAPPPPPPPPRHVVSPTRGFGAYHHHHHHHHHHQYSEGNVFAGPINPRIRNRRNGLTGRPKMHSKGETSSLKTGVIDFAAGCLGGVALVYVSQPMDTVKVKMQTFPELYGGLVNCTVQTFKRDGLVRGLYAGTLPAVVANVAENSVLFAAYGACQQVVGSAVKKPSVAELSTLENATAGFLAAFFSSFTLCPTELIKCKLQALRETAGSDGKRRPTISSYALVSQILRTEGVAGMFRGLTSTFAREMPGYFFFFGGYEQTREFLAKPGQTKDEIGALRTMVAGAVGGVALWTVIFPADVIKSRIQVYSMRASMTQVGLDIFRKEGVLAFYNGLLPTIVRTIPATAVLFVVYEYTKKTLTKLLE
Length2734
PositionKinase
OrganismAnopheles stephensi (Indo-Pakistan malaria mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.06
Grand average of hydropathy-0.852
Instability index53.70
Isoelectric point5.88
Molecular weight302019.19
Publications
PubMed=25244985

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-UniRule

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08222
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             9|     307.70|      23|      23|    2156|    2178|       1
---------------------------------------------------------------------------
  256-  276 (26.96/ 7.63)	...QQ...QQQQEHPPDGQ.Q..QQlEQHP
 1256- 1277 (37.67/13.93)	SLHQQ...HQAQLQPPLQQ.Q...Q.QQQQ
 1344- 1366 (25.72/ 6.90)	NADVL...QKDAELHQQKL.L..RQ.QQQQ
 1382- 1405 (27.96/ 8.22)	TVDQA...TGSQMQHHQHDlH..SD.PQHS
 2144- 2164 (38.61/14.48)	SEREQ...QQQQ..PQQQQ.Q..QQ.QQQQ
 2165- 2187 (50.46/21.45)	QQQQS...QQQQHHHQQQQ.Q..QQ.QQQQ
 2188- 2207 (42.24/16.62)	HHQH.....QHQHHH.HQH.Q..SQ.QQQQ
 2208- 2228 (33.73/11.61)	QQQQQ...QQQ....QQSQ.QhsQQ.QQQQ
 2229- 2254 (24.36/ 6.09)	QQQESfqlEQTQLQHLVQE.H..VQ.NQDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.11|      23|      23|     353|     375|       2
---------------------------------------------------------------------------
  322-  344 (22.46/11.87)	...G.KMvsfSD...KALADEPSNPSHREE
  353-  375 (43.42/32.24)	DEDG.GM...ED...DEDEDQEEEDEEEEE
  377-  403 (32.24/21.37)	DEEGeEM...EEedgEEEEDEEEEDEEEEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.82|      20|      23|    1295|    1314|       3
---------------------------------------------------------------------------
 1300- 1320 (36.55/20.58)	SQHLQ.QQSPPHPQLDyPNTPP
 1322- 1343 (26.27/11.92)	SQHLStHPSTAQQQLQlGSVLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.29|      11|      18|     711|     721|       4
---------------------------------------------------------------------------
  711-  721 (22.26/14.86)	NGEDMDDEMDD
  730-  740 (21.02/13.54)	EDDDVDDEDDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.39|      18|      25|    2284|    2306|       5
---------------------------------------------------------------------------
 1412- 1431 (30.57/14.12)	MAKADQEEQSMHHH.....HHHhqQ
 2293- 2315 (26.82/12.67)	MVSLDLSSNTGSHHavnngSHH..A
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.15|      18|      18|    2100|    2117|       7
---------------------------------------------------------------------------
 2100- 2117 (32.91/20.08)	DFQ.GLDMSSRSSVSAYHH
 2119- 2137 (30.23/17.73)	NFQlSTQAGSNLHFNRYHH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.43|      17|      19|     977|     994|      10
---------------------------------------------------------------------------
  977-  993 (36.70/23.17)	CGGCNLKFDHPFYY....RTH
 1040- 1059 (24.82/11.08)	CQFCQ.KFFLRLNYlemhRTY
 1072- 1088 (31.91/18.23)	CDFCGRKFCQPQKL....KVH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.15|      14|      23|    1209|    1225|      11
---------------------------------------------------------------------------
 1209- 1225 (17.59/19.89)	GGLNdGiiDEVQRRQRH
 1233- 1246 (23.57/12.90)	GGYP.S..EKVERKKRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     100.87|      24|      24|    1666|    1689|      12
---------------------------------------------------------------------------
  805-  824 (28.56/10.99)	....PPDVAPQHQEQQD...QDSIMES
 1653- 1676 (37.94/17.21)	VNTPPPNVADDEEEDDD...NSTILDV
 1677- 1703 (34.37/14.84)	VDSNNPNQQSTHAQIQQytsNFTGLNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.78|      26|      27|    1126|    1151|      13
---------------------------------------------------------------------------
 1093- 1121 (39.89/30.76)	HSDMADV..LrdfQCK..LCSKLLGSRAALQRH
 1126- 1151 (46.90/37.91)	HSRNSAV..V...SCP..RCQKLFQNRSNLKIH
 1155- 1181 (32.99/23.74)	HS...GVrpF...KCAenECTAAFTTKQCLQFH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.83|      18|      25|    1891|    1908|      14
---------------------------------------------------------------------------
 1891- 1908 (32.12/23.12)	TPHKLTS..SVDSV.RSALSP
 1919- 1933 (26.68/17.45)	TPS..TS..SRQHI.VSG.SP
 1943- 1963 (22.03/12.61)	AEHDLISpaSTPSLpRYDFGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     132.81|      25|      26|    1597|    1621|      15
---------------------------------------------------------------------------
 1488- 1508 (22.88/10.67)	GTSAG...SNGGN..VEDIRK....niIDH
 1509- 1528 (27.67/14.85)	QG.....LEEGRSDRLDDMQHL.....VHP
 1529- 1555 (20.52/ 8.61)	LPDDQ...SKANSLNVSQLHRLnisnqLDT
 1600- 1626 (35.53/21.70)	GGNAGLVISKGSKKWISDTDQL...pgVDG
 1628- 1651 (26.21/13.58)	QGEPGVMLST.....VSGRDFL.tkliMNG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.68|      17|      19|    2045|    2061|      16
---------------------------------------------------------------------------
 2045- 2061 (31.29/19.30)	GGGTSATEFIQHQKYGE
 2067- 2083 (30.39/18.50)	GGSNLSTTADMRIKYGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.82|      11|      18|    1706|    1716|      18
---------------------------------------------------------------------------
 1706- 1716 (21.16/11.65)	LPSFQSHAFQG
 1724- 1734 (20.66/11.17)	LGSFYNNSGTG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.85|      15|      27|    1770|    1790|      19
---------------------------------------------------------------------------
 1770- 1790 (22.50/22.77)	NNNGGTNSnnqnqgLNINHID
 1800- 1814 (27.34/12.71)	NNNVSANS......FNASNID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.34|      10|      19|    2013|    2022|      20
---------------------------------------------------------------------------
 2013- 2022 (16.23/ 9.85)	AENLSVNAVS
 2035- 2044 (18.11/11.98)	ATNANNNAPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.75|      16|      18|     529|     544|      21
---------------------------------------------------------------------------
  529-  544 (29.67/19.79)	EELPTTSNFFDQCDFD
  549-  564 (26.08/16.36)	DEKPATLPLVKKGALD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.48|      16|      18|    1974|    1991|      23
---------------------------------------------------------------------------
 1974- 1991 (21.07/18.66)	RQDAKTISSLTleSFESN
 1993- 2008 (28.41/18.09)	KDTAHHMQQLS..SDEDN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.67|      17|      18|    2501|    2517|      24
---------------------------------------------------------------------------
 2501- 2517 (27.28/19.69)	YAGTLPAVVANVAENSV
 2522- 2538 (29.39/21.91)	YGACQQVVGSAVKKPSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.76|      14|      18|     288|     304|      25
---------------------------------------------------------------------------
  288-  303 (18.17/17.48)	FtsSKAAGSIGKKTKR
  306-  319 (24.58/10.55)	F..NKNVNIIHKLDNR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.72|      20|      25|     836|     858|      26
---------------------------------------------------------------------------
  836-  858 (29.16/29.74)	SSFVGTLGTErdpAPKSRPVSGH
  861-  880 (33.56/22.68)	SIYTTTFIAK...YTKIGPLTGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.96|      32|      43|     883|     917|      27
---------------------------------------------------------------------------
  883-  917 (49.92/54.13)	RETEiQDDCTMR.H...IFetFDGVKSTYTSTENKNFSN
  926-  961 (50.04/40.10)	RNRE.QKNCVLQvHdggIY..FVTSKDLEPGTELLYWSN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08222 with Med12 domain of Kingdom Metazoa
Unable to open file!