<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08214

Description Uncharacterized protein
SequenceMTTAVMMDYEFKMKTQQERAKVEDLFEYEGCKVGRGTYGHVYKARRKEGNDAKDYALKQIEGTGLSMSACREIALLRELKHPNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTKDFKRSNYASCSLVKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQNQQGNQQQQQQNQQQSGNPMQQGGGAGGAGGGGQGGGGMDHNNAKRVRLAGPNGHPNNSQGGMTQQEYHQQQQQQNQQQQQQNQMMFNSGQQGGFQQRY
Length516
PositionKinase
OrganismAnopheles quadriannulatus (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.08
Grand average of hydropathy-0.996
Instability index58.19
Isoelectric point8.76
Molecular weight59711.51
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08214
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     153.74|      18|      18|     377|     394|       1
---------------------------------------------------------------------------
  377-  394 (39.99/11.40)	RQQQQQQQQQQQQQQQQQ
  396-  413 (40.10/11.45)	QQQQQQQQQQQQQQQQQQ
  414-  431 (36.64/ 9.96)	NNQQNQQGNQQQQQQNQQ
  484-  501 (37.01/10.11)	EYHQQQQQQNQQQQQQNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.58|      12|      29|     442|     453|       2
---------------------------------------------------------------------------
  442-  453 (23.80/11.03)	GAGGAGGGGQGG
  468-  479 (25.78/12.51)	GPNGHPNNSQGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.94|      16|      26|     245|     267|       4
---------------------------------------------------------------------------
  245-  262 (22.79/30.16)	EDIKtSNPYHHdQLDRIF
  274-  289 (31.16/13.66)	EDIR.KMPEHH.TLTKDF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08214 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQNQQGNQQQQQQNQQQSGNPMQQGGGAGGAGGGGQGGGGMDHNNAKRVRLAGPNGHPNNSQGGMTQQEYHQQQQQQNQQQQQQNQMMFNSGQQGGFQQRY
326
516










Molecular Recognition Features






MoRF SequenceStartStop




1) GFQQRY
2) MDHNNAKRVRLAGPNGHP
3) TQQEYHQQQQQQNQQQ
511
456
481
516
473
496