<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08209

Description Uncharacterized protein
SequenceMMNPNHSGASRRPYSRGAVPRNRSRMPFSPHHSHHANRNHGGHNQSWYNKDMENSFNYGDSGSSPKESSFTYTSKSPPVQLHSPPIAGRPTAATILMPYGAADDGSINNRSQQILRAGPSHIDRHRINMGGNSMQERNRHTMSASSIDRHLNHFEGPSNSTRGADLHGGDARSVLSMDSMRNSRDNNGGARERFSPHYHPGGGSGGGGGSGGGNGSGPAGGSNQGSSPPYCPVDGIGGNGGIKSDSPSRKRRRVSSRLPSQSPPAAIWEQRRSPRNGGGMMSLMGTSGANGGGNGQGSNGGLGNHGMNGHHSMSQQQQQQQQPQSSQSGQQQQLVPPQLHHRDHPQPHHHHPMHHHHHHSQQQQQQQQQQQQSHHHTNGGGSHLHPSSGGGLAAAVISQLQSHAHHPQGSPPIRRPRFHRDQQSQQQQQPQQQQQQQPQQQQRPWESLTQVFQQAPAAQAQHQHPASSLMVDINQVPVSLPLGHHHEQLWTYSAGPHISICSGHPAAPHLPPCQVHGVYSQPFAQTCGIGGHFGGFASSAGPALAVPHPPPHQAHYQHPHLAQQRTDGLTLDGLEHAGGSPLHLSPLATHAHHLHGASPQMTQLTAAAQPIYISTEVSAVGSEVPRTGVTPAGTLIPLIANVPQGRNYEILHRTVRRAITAPRRNFARFHWPGPPPPPPPPPPPAHHQHHHPGHHPTHHHRPHAPPPPAALQAHPQPLGHPQPAHVTLSATTSAYSGILLNFLAMFPLSSYGPPDLNSPDSNETENYEALLSLAERLGEAKPRGLARPEIDQLPSYKFNAETHTGDQTSCVVCMCDFEARQILRVLPCSHEFHAKCVDKWLRSNRTCPICRGNASEYFESSEEQ
Length864
PositionKinase
OrganismAnopheles quadriannulatus (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.05
Grand average of hydropathy-0.931
Instability index70.09
Isoelectric point9.39
Molecular weight93558.86
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
metal ion binding	GO:0046872	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08209
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     188.51|      41|      49|     296|     336|       1
---------------------------------------------------------------------------
  202-  235 (43.95/ 7.84)	GGSGGGGGSGGGNGSGPAGGSNQGSSPPYCPVD.....G.......
  296-  336 (81.20/21.52)	QGSNGGLGNHGMNGHHSMSQQQQQQQQPQSSQS.....GQQQQLVP
  342-  386 (63.36/14.97)	RDHPQPHHHHPMHHHHHHSQQQQQQQQ.QQQQShhhtnGGGSHLHP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     184.69|      31|      32|     662|     692|       2
---------------------------------------------------------------------------
  460-  516 (37.06/ 7.81)	AQHQHPASslmvdinqvpvslplghhheqlwtysagPHISICSG....H.PAAP.HL......PPC...QVH
  554-  590 (38.25/ 8.30)	AHYQHPHL..........................aqQRTDGLTLdgleHAGGSPLHL......SPL...ATH
  654-  684 (57.59/16.37)	TVRRAITA............................PRRNFARF....HWPGPPPPP......PPP...PPP
  685-  723 (51.79/13.95)	AHHQHHHP............................GHHP.THH....HRPHAPPPPaalqahPQPlghPQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     119.82|      24|      24|     110|     133|       3
---------------------------------------------------------------------------
    8-   41 (34.61/14.52)	GASrrpysrgavpRNRSRMPFSPHHSHHANRNHG
  110-  130 (31.91/12.75)	.............RSQQILRAGPSHIDRHRINMG
  152-  168 (22.56/ 6.64)	...............NHF..EGPSNSTRGADLHG
  169-  188 (30.74/11.99)	GDA..........RS..VLSM..DSMRNSRDNNG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.61|      22|     141|     254|     275|       4
---------------------------------------------------------------------------
  254-  275 (40.44/18.95)	VSSRLPSQSPPAAIWEQRRSPR
  418-  439 (38.16/17.38)	FHRDQQSQQQQQPQQQQQQQPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.47|      19|     141|     390|     412|       5
---------------------------------------------------------------------------
   88-  106 (32.61/11.57)	GRPTAATI..LMPYGAADDGS
  390-  410 (28.86/23.48)	GGLAAAVIsqLQSHAHHPQGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.52|      28|      31|     729|     759|       6
---------------------------------------------------------------------------
  729-  759 (37.46/33.89)	SATTSAYSGiLLNfLAMfPLSSYGPPDLNSP
  761-  788 (48.06/27.40)	SNETENYEA.LLS.LAE.RLGEAKPRGLARP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.09|      16|      44|     479|     495|       7
---------------------------------------------------------------------------
  479-  495 (29.14/16.51)	SLP......LGHHHEQlWTYSAG
  520-  541 (24.94/ 9.58)	SQPfaqtcgIGGHFGG.FASSAG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08209 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSPLHLSPLATHAHHLHGASPQMTQLTAAAQP
2) MMNPNHSGASRRPYSRGAVPRNRSRMPFSPHHSHHANRNHGGHNQSWYNKDMENSFNYGDSGSSPKESSFTYTSKSPPVQLHSPPIAGRPTAATILMPYGAADDGSINNRSQQILRAGPSHIDRHRINMGGNSMQERNRHTMSASSIDRHLNHFEGPSNSTRGADLHGGDARSVLSMDSMRNSRDNNGGARERFSPHYHPGGGSGGGGGSGGGNGSGPAGGSNQGSSPPYCPVDGIGGNGGIKSDSPSRKRRRVSSRLPSQSPPAAIWEQRRSPRNGGGMMSLMGTSGANGGGNGQGSNGGLGNHGMNGHHSMSQQQQQQQQPQSSQSGQQQQLVPPQLHHRDHPQPHHHHPMHHHHHHSQQQQQQQQQQQQSHHHTNGGGSHLHPSSGGGLAAAVISQLQSHAHHPQGSPPIRRPRFHRDQQSQQQQQPQQQQQQQPQQQQRPWESLTQVFQQAPAAQAQHQHPASSLMVDINQVPV
3) PRRNFARFHWPGPPPPPPPPPPPAHHQHHHPGHHPTHHHRPHAPPPPAALQAHPQPLGHPQPAHVTLSA
4) SAGPALAVPHPPPHQAHYQHPHLAQQRTDGLTLDGLEHA
579
1
662
539
610
478
730
577










Molecular Recognition Features






MoRF SequenceStartStop




NANANA