<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08177

Description Uncharacterized protein
SequenceMVERIVEESCDVNSDPTRKADVARYSSEEVSGNESTETRMLSEAERQADFNRHKEEMKRKRRRKKRASSSMQSACFQECYKLTGEVLGEGAYASVQTCINIFTDLEFAVKIIDKIPGHARGRVFREVETFHHCQGHPNILQLLEFFEDDEKFYLVFEKINGGPLLTRIQENVCFSEYDAAQIIMEIASGLDFLHKKGIAHRDLKPENILCVYPDKLCPIKICDFDLGSGIKFTTNISSPTATPQLLTPVGSAEFMAPEVVDLFVGESNYYDKRCDLWSLGVIAYILLCGYPPFSGNCEQDCGWNRGENCRTCQELLFESIQEGRYCFPDSEWQDVSEEAKDLIRGLLVKDAPKRLSASAVLNHPWIRISDDTECSVGGPNAKANKDKQRLRVLKTPGVIRRNRSALELSHFAESAMAVKRVILQHFSMRYDYMTKERPNIYQPSYNGNVERAPVVPDKPTLTVAETTTQKSANFNDAVPALPRREPPKGVWGKDEKLKATYEAKESWEMTTNVVEPEKQEKEKEREKDSYQNVSIECQNVAGTNGVESVATIANDETVVGAATIQIVVNSMSSGTDGGTMPTTTTNNNNTTAIGSITNGHDEASTNNGNSETKKMSDEELQNSDPPKTVAEGDGKTEVPQGKAVVVTILPQARVSPPTSALSSPVHSKDSTATRKASSSWDIPPESNWRYRGGNGTDQQSPSSFENSSRLQQAHNNRHIGSSYKGGRSGHYHSHPQQQQHHHYQGNNAHYNYHHHHNNHHSHPASSYRQQNGGHNNYHSLSQGNHYNQNHYNSNGSNTGRYGRVVRVGINSDQFITGMMMKQRQPSQNYAYNHQQPNHGSSASLPSWRAQPSSATYGKASTDEGENYRYSNGKYSNGGTVTATPMSHYENGKTSSNPTNFNHHQYNRGGTNNNISNNTSNVSSSGGSGSHHPARMNGGNSSHHQSQYHHHQQQQQHHYGAMNNNSSNNHFYSNGSGAGGGMGHYNYSNNHHYGTVNGHGGQQQLQQQQHKSLPYRVISHHHHHHQPQQQQQQQYQNQRYASASSFGGMRRPSQGLTDTVDGTKGTGARRASFGQQQPTIQRPSPPQQQKQQQQQQQQQSRSNVNCDPTTNTMNRYKLYHSNSILSALKRETRKNGYQSMMVGGFEGLTLNGEGGDPYQLADEGEEVTVDQTTPYHLIPHHKAEQQEQQDAIDNIDEAVYSSSSSSNTSSHSGNSIINGNVATTTMAALGGNTGGPRIIADFAMSEGLPVGLSPPNESLLMQRRLSLKSRSLCLPVAIGLGGGIVPSLAVSSIMPPSGDEFPVCSPTCQQGQEQHEQESPLPSPEQLAQSDEDAGGCPIFATTGPEAGGYYTYYPHNGTVVVPGTTPTLTITTQSG
Length1375
PositionKinase
OrganismAnopheles minimus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.07
Grand average of hydropathy-0.881
Instability index54.61
Isoelectric point6.52
Molecular weight151804.77
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08177
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     527.00|      65|      65|     971|    1035|       1
---------------------------------------------------------------------------
  605-  681 (59.93/19.99)	T.NNG..NSET..KK......MSDEEL....Q......N....SDP..............PK....TVA...EGD.GKT.EV.......PQgkavvvtilpQ.AR.....VSPPTSAL....SSpvH...SKDSTATRK.....ASSSW........D
  690-  744 (69.49/24.28)	Y.RGG..NGTDqqSP......SSFENS....SrlqqahN....NRH..............IG....S.S...YKG.G.............R..........S.GH.........Y.................HSHPQQQ.....QHHHY........Q
  746-  788 (43.63/12.66)	..............N......NAHYNY................HHH..............HN....NHH...SHP.ASS.YR.......QQ..........NgGH.....NN..YHSL....SQ..G...NHYNQ.......................
  789-  845 (41.83/11.85)	......................NHYNS..ngS......N....TGR..............YG....RVV...RVGiNSD.QFitgmmmkQR..........Q.PS.....QNYAY................NHQQPNHG.....SSASL........P
  869-  967 (54.98/17.76)	Y.SNG..KYSN..GGtvtatpMSHYENgktsS......NptnfNHHqynrggtnnnisnnTS....NVS...SSG.G............SG..........S.HH........PARMNggnsSH..HqsqYHHH..QQQ.....QQHHYgamnnnssN
  971- 1035 (128.99/51.02)	Y.SNG..SGAG..GG......MGHYNY....S......N....NHH..............YG....TVN...GHG.GQQ.QL.......QQ..........Q.QH.....KSLPYRVI....SH..H...HHHHQPQQQ.....QQQQY........Q
 1039- 1097 (72.11/25.46)	Y.ASA..SSF...GG......MRR.......P......S....QGL..............TD....TVDgtkGTG.ARR.AS.......FG..........Q.QQ........P..TI....QR..P...SPPQQQKQQ.....QQQQQ........Q
 1118- 1200 (56.03/18.24)	YhSNSilSALK..RE......TRKNGY....Q......S....MMV..............GGfeglTLN...GEG.GDPyQL.......AD..........E.GEevtvdQTTPYHLI....PH..H...KAEQQEQQDaidniDEAVY........S
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.35|      23|      78|     208|     231|       2
---------------------------------------------------------------------------
  208-  231 (40.23/28.04)	ILCVYP..DKLCPiKICDFDLGSGIK
  286-  310 (44.12/26.39)	LLCGYPpfSGNCE.QDCGWNRGENCR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.31|      21|      31|     485|     515|       4
---------------------------------------------------------------------------
  493-  515 (31.73/39.16)	KDEKLKAtyEAKESW........EMT.TNVVE
  518-  547 (24.58/ 6.31)	KQEKEKE..REKDSYqnvsiecqNVAgTNGVE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08177 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DVARYSSEEVSGNESTETRMLSEAERQADFNRHKEEMKRKRRRK
2) EFPVCSPTCQQGQEQHEQESPLPSPEQLAQSDEDAGGCPIFA
3) GAATIQIVVNSMSSGTDGGTMPTTTTNNNNTTAIGSITNGHDEASTNNGNSETKKMSDEELQNSDPPKTVAEGDGKTEVPQGKAVVVTILPQARVSPPTSALSSPVHSKDSTATRKASSSWDIPPESNWRYRGGNGTDQQSPSSFENSSRLQQAHNNRHIGSSYKGGRSGHYHSHPQQQQHHHYQGNNAHYNYHHHHNNHHSHPASSYRQQNGGHNNYHSLSQGNHYNQNHYNSNGSNTGRYGRVVRVG
4) NIYQPSYNGNVERAPVVPDKPTLTVAETTTQKSANFNDAVPALPRREPPKGVWGKDEKL
5) NSDQFITGMMMKQRQPSQNYAYNHQQPNHGSSASLPSWRAQPSSATYGKASTDEGENYRYSNGKYSNGGTVTATPMSHYENGKTSSNPTNFNHHQYNRGGTNNNISNNTSNVSSSGGSGSHHPARMNGGNSSHHQSQYHHHQQQQQHHYGAMNNNSSNNHFYSNGSGAGGGMGHYNYSNNHHYGTVNGHGGQQQLQQQQHKSLPYRVISHHHHHHQPQQQQQQQYQNQRYASASSFGGMRRPSQGLTDTVDGTKGTGARRASFGQQQPTIQRPSPPQQQKQQQQQQQQQSRSNVNCDPTTNTMNRYKLYHSNSILSALKRETRKNGYQSMMVGGFEGLTLNGEGGDPYQLADEGEEVTVDQTTPYHLIPHHKAEQQEQQDAIDNIDEAVYSSSSSSNTSSHSGNSIINGNVATTTMAALG
6) YEAKESWEMTTNVVEPEKQEKEKEREKDSYQNVSIECQNVAGTNGVESVATIANDET
21
1299
560
439
810
501
64
1340
808
497
1229
557










Molecular Recognition Features






MoRF SequenceStartStop




1) GYYTYYPH
1348
1355