<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08176

Description Uncharacterized protein
SequenceMSSYHLSTRERLLAIINDIEIVAKELIENTIAPKAQKMSSTDHAQLVELLVLKDKELKSTLQLAAEQAGIEKNMDALREQVRKQDEEINQLQKQLKEAEQILATSIFQARQKLASITKANKRPVSSEELIKFAHRISASHAICAPLTWQQGDLRRPYPTDIEMRLGFLGKSDLNINGHNLQHPNSLNEMHRNTSVSGAAGGAGAGGEIPASAQNQFAWHPSGELHMSMGAGGGSVSLDTRAHKDASQDDVEVIIMDPNRSPFDEEADRISQMQRMRSLDGHRFFTRSNSSNGTQNVLLKVLNREHSGYLSTGLNKRSHQQPFQEVPEQLQFCLKSIVPYCFLSGHIFMGLTSCGQFLLSYKLSYDYDEAFANDFCSIHKYELYFWIYRPHVLLSKYFHVCLFDDHGVGEIKSVSITQWKTDSQLLIVHGGNLNEDSESYVTMVRVPKLGCLDCKQVRDAHEGDEQRQDILCIGCNMTIHMKYRGTDSGPRFNPNFNLNCPGYVIMSENSIIHTINVKLDTRRSQESVGSSATLSSKYLGHVSPQKDTPEECKKQTTPCKGTDATVVAKQHECTGTAKKGDIESVRSDGPASSTLLNPELSIAEQIIADFAEYETDMYETKCSIRSYPDNFDELIITSPIASTVQQESTTEPGMAQVRLMNHRNNTNIELRLDGASGGASCSSTSAGMAGPSAKTAASIVPPRKSFVTRVDLQCGGGSSPCQEGFGSVRAVVNPSSVPMCDMSFTASSSTTALAPSISRSPLRRRFDLSDSSYVPNAQIAHQQSKLPLQQCVVNGANGANFQVASEASGLEPDSVDSAAKAYEFSEDNERCEKISAFRKRRLADKKYEFSEEPTSEENIEPFNRLRNQIRARVTAPGYSASHHHASYADLISTTHHLHRASPNHGFRSPCGSPVGNRYLRSPPGIRSPSYYRHRSPSSQGQQPGCGSVMLGGGIAPGASVTAAPIKQVKRNVSVDPRDYIQILSPGNGISAGGSSEAGGTPDIPKFFLDAVQKVNAKRIANELLLLDESNNENNINGDNQLPTKQQSGGCVDASSESSKPGAEMPTCTKRIVKIFVEEDDANSVVTMEDDDCISPGYHASLPMEVHGSCYSKMQIISQASFNKLNCPAVVVTQNSFDMEVFSFHVANYICAQESKKYGILLDSAYELTHVCPLTETITCTTVLQFTANDIGNSKPKPCQNCSATIDCQTHRKIYQCRSLFTWCITTGEWMILDYGHLTSGPYLEVKKLASNYNYLLKKLRSFTTKLFTSEGQNESNRTYEYLNHLRVLDSDTKKAKRRLTDLDNMIELYLRRPRRGDDYSGTDSDSYGEEDDEEEEEEEEEEEEEEEDNEEDEHVDSSSDDW
Length1361
PositionMiddle
OrganismAnopheles minimus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.07
Grand average of hydropathy-0.558
Instability index56.70
Isoelectric point5.56
Molecular weight150682.53
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
protein ubiquitination	GO:0016567	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08176
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.51|      30|      32|     882|     911|       1
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  882-  911 (57.14/30.89)	HHASYADLISTTHHLHRASPNHGFRSPCGS
  917-  946 (58.37/31.71)	YLRSPPGIRSPSYYRHRSPSSQGQQPGCGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.22|      23|      30|     690|     718|       2
---------------------------------------------------------------------------
  694-  718 (35.63/31.52)	TAASIVPPrkSFVTRVDLQCGGGSS
  726-  748 (38.59/17.00)	SVRAVVNP..SSVPMCDMSFTASSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.14|      12|      32|     950|     961|       3
---------------------------------------------------------------------------
  950-  961 (22.24/15.97)	GGGIAPGASVTA
  985-  996 (21.91/15.59)	GNGISAGGSSEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.96|      24|      24|     817|     840|       4
---------------------------------------------------------------------------
  817-  840 (43.10/28.19)	AAKAYEFSEDNERCEKISAFRKRR
  842-  865 (43.86/28.83)	ADKKYEFSEEPTSEENIEPFNRLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.20|      15|      32|     640|     654|       5
---------------------------------------------------------------------------
  640-  654 (27.03/14.81)	ASTVQQESTTEPGMA
  674-  688 (27.17/14.93)	ASGGASCSSTSAGMA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.71|      10|      32|     188|     201|       6
---------------------------------------------------------------------------
  188-  201 (14.99/16.37)	EMHrntsVS.GAAGG
  223-  233 (16.72/ 7.08)	ELH....MSmGAGGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.33|      22|      30|     528|     557|       7
---------------------------------------------------------------------------
  531-  556 (32.07/34.48)	ATLSSKY.........LGHVSPQKDTPeECkkqTT
 1150- 1180 (33.27/14.57)	AQESKKYgilldsayeLTHVCPLTETI.TC...TT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.85|      14|      34|     306|     322|       9
---------------------------------------------------------------------------
  306-  322 (17.93/19.05)	SGYLSTGLNkrSHQQpF
  343-  356 (28.92/15.68)	SGHIFMGLT..SCGQ.F
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     271.71|      85|     623|     417|     509|      10
---------------------------------------------------------------------------
  417-  509 (141.76/121.95)	QWKTDSQllivHGGNLNEDSESYVTMVRVPKlgCLDcKQVRDAHEGDEQR.....QDILCI..GCNMTIHMKYRGT.DSGPRF..NPNFN.LNCPGyVIMSENS
 1039- 1134 (129.95/87.48)	QLPTKQQ....SGGCVDASSESSKPGAEMPT..CTK.RIVKIFVEEDDANsvvtmEDDDCIspGYHASLPMEVHGScYSKMQIisQASFNkLNCPA.VVVTQNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.03|      22|      24|     760|     783|      12
---------------------------------------------------------------------------
  760-  783 (33.40/25.02)	PLRRrfDLSDSSYVPNAQIAHQQS
  786-  807 (37.63/21.40)	PLQQ..CVVNGANGANFQVASEAS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08176 with Med4 domain of Kingdom Metazoa
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