<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08168

Description Uncharacterized protein
SequenceMTTAVMMDYEFKMKTQQERAKVEDLFEYEGCKVGRGTYGHVYKARRKEGNDAKDYALKQIEGTGLSMSACREIALLRELKHPNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTKDFKRSNYASCSLVKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQNQQGNQQQQQQNQQQSGNPMQQGGGAGGAGGGGQGGGGMDHNNAKRVRLAGPNGHPNNSQGGMTQQEYHQQQQQQNQQQQQQNQMMFNSGQQGGFQQRY
Length514
PositionKinase
OrganismAnopheles merus (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.08
Grand average of hydropathy-0.986
Instability index57.63
Isoelectric point8.76
Molecular weight59455.25
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08168
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     158.18|      18|      18|     378|     395|       1
---------------------------------------------------------------------------
  373-  391 (29.66/ 8.56)	KGEKrQQQQQQQQQQQQQQ
  392-  410 (33.08/10.41)	QQQQqQQQQQQQQQQQQQQ
  411-  428 (34.75/11.32)	QNNQ.QNQQGNQQQQQQNQ
  463-  480 (25.52/ 6.33)	RLAG.PNGHPNNSQGGMTQ
  481-  498 (35.17/11.54)	QEYH.QQQQQQNQQQQQQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     195.73|      55|      86|     215|     271|       3
---------------------------------------------------------------------------
  215-  271 (91.40/83.01)	RHYTKAiDIWAIGcIFAELLTSEPIFHCRQEDIKTSNPY.HHDQLDR..IFNVMGFPQDK
  274-  296 (18.20/ 6.92)	..............................EDIR.KMPE.HH.TLTK..DFKRSNYAS..
  305-  361 (86.12/66.60)	RHKIKP.DSKAFH.LLQKLLLMDPNKRITSEQ.AMQDPYfSEDPMPTadVFAGCPIPYPK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08168 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNNQQNQQGNQQQQQQNQQQSGNPMQQGGGAGGAGGGGQGGGGMDHNNAKRVRLAGPNGHPNNSQGGMTQQEYHQQQQQQNQQQQQQNQMMFNSGQQGGFQQRY
326
514










Molecular Recognition Features






MoRF SequenceStartStop




1) GFQQRY
2) MDHNNAKRVRLAGPNGHPNN
3) MTQQEYHQQQQQQNQQQQQQNQMM
509
454
478
514
473
501