<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08159

Description Uncharacterized protein
SequenceMNMRPLKRPRLGPPDVYPQEAKQREDELTSTHVKHGFATEHKLSEEFGTARNCNVSASKVGAYFNAILAKKEELMTLPDSGRKKQQINPKDNFWPVTARNKTTLDTWFKDLAGTKPLSSLAKKAPSFNKKEEIFAMLCENQVTMQRAAWFIKLSSAYTVAVSEAKIKKRQMPDPATEWTGTMIKFMKDLIPKLHEHYHQGPLQEKPSSGGAGSSGGLGSGASGLGLSSGAGGTNAVTIPPPLSSPAGSMHSPAGGNPVVGGSMHAQQQQQQQQQQQQQPISPQEEQRIAQKQWNYSTQLCKYMYEEGLLDKQEFLNWIIDLLEKMKSSPNADDGLLRIYLPLAMQYLYDLVQSERFCRRLAYAVSKKLAQLINQMAESHNINLSSPEPQDASGKQPSIEAPESKSEKQNDKPSKEGTAGTVAQPADTKPPKVNPYEMIFTEYLQCSHHRDVILQLSSILQVITLECPTALVWCGVGETRSSSVLSGSPLDHLPVAPSALPIPTRYEKSNEDIRRQLFEAEESIKVRSRHAESRWCIDKWQTAAGNASLKILATLDALDGHCFDRMDSNNSLDSLYSKIFPPFQVQPLKPAESASAAGGSGGSGTGNMPSGLAAVDGKDAATKQFEYNVEQDSSIVKILCEWAVSWQRWGEHRAMVVAWLLDKRQNEVLTALENDSYTNNLNNSDDKDSVLSGSGLNGGQPVFQHILMNFLDHDAPVLDEAGSPQNKSQFTNLVHLFSELIRHDVFSHDAYMCCLISRGDLLTGAGGMLSLDSQGICNAGLGTGPISNKPATSSSPNGGGGVEDDVLQTDFKAKLEDLDDSNVDDDLDKLLQHIKEDQQNSMDAPDSPKDPEHAAPSVTGLGKAESSSRHFLYTEHFPLCQDDPISQHDCNQRYILLYGVGKERDEKKHAVKKMSKEICKLFSKKFSIDVAEGGKVKKHSRSEFNFESTSNKCQAMSYFDQHVVTWQCAVQVQEMLNAFAIGNSNYLPVQEHVAFLFDLMESAFNIYGLIDTCIQILRELPEVELQLIGKSSMALVRSYTTSLSLYVVGVLRRYHCCLLLSQEQTTAIFEGLCRIVKHVSNPSDCSSAERCILAYLYDLYSACSSLKARPQQEPFHNAYPKIKQALYTPLQPTPSAHTYNPQFMLDIITNPRRGGKIESGWARQLNESASNRYSFVCNAVVAVTRDIDNDCLNDIAAMCAELTACCNSLSTEWLGVLIALCGSNRDAGYYVDVLTQVDVQNTNIHNALSVFTSILVARHCFSLENFVAHVALPSLVQACKGRGETTPEIEAGARLSCHLLLRLFKTIECPQPGLYSVSTSPNPITVGNAHNIKLSCDRHLLAAAHKNIGVAPVLAVLKGILVVGDATAHKVSSIFGTGKRSGLNTPVHPGSTPKSMAGSGDLSHILGTSDLSILGNPDESMLDVSMIELGELSPTASARLYSSRQQNSHLNQDNATSLSDFAQHVLRQICSQEWVLERCLQHAEELCQHGMLIDNLLTAKQAQRLLHMICYPEHESNLIAELEQKAIIVRILENLEQWSLRISWLDLQLMFKQTNCSSPDLSNWLDMVARAAIDVFRVNEFILNSPDVKQEKVKPSTWLVAPLVSKLPSAVQGRILKVSGQVLESTSMFSKHKDGNGGNNSSNNNSHNHGANSNSSVSSNGSTFGSKQSAQLNHQPFLGLVLTCLKGQDEQKEGLLQSLYSQLSQFLQNRDQSLETIGGIEDPCGFEKMLDALQLRYSLVGGLFDAIMKNATSTTDWAILFAQLISQGVIDLSNNSELFTTTLDMLATLIHSTLVSDSQTERDENKKLYTNLMKKLRKELGDKNGPSIKYVRQLLPLAKQTCEVLTCDSAGSSTDAKGNKIAIDSIEKKNGLRLGDKQRVSVWDLLEGHKNPAPLSWAWFGAVKIERKPLAYEETHRLLKYHTHSLFKPSSYYYEPLPLPPEEVDPLPDKLKDDMKADTPSSDQSPAPSTGSKKSKTTTRKRKTKATAAAQVQQSQPQQPIMPAIVPQPAAGPQQMQQMQQQQQQQQQQQQQQQQQQHQQHQQQQQQQQQMQQQQTLQQQQHLQQQQQQLHLQQQQAQQQQQLQQQQQLQQLQQQQQQQLQQQQQQQQNQMMMQQQQQPNIPQQQQSALQQQQLGSQQGQQQQQQQVTMTPQQTLQQMQNNSMGGMQMGGPMSSMNQQHMQQQYGQANPAQLVGQGNMGGMQTGMGGLGAGMGGGMMNQQQQQQQQQQQQQQQQQQQPPQQQQPQQAQQAQQAQQAQQQQPQGNPNMGFVGNVNPMAQLAQQQGGNQQWGGYGSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQSQVQQQQQTPQQGQQASQQQGPQQGPQQGAQQGPQTQQQLQQQQQQQQMFYSGMGQATMNRFDRPQLNTNSKQALSNMLRSKLPINAGHPASFMQQQQQQQQQQQQAQRNPQQPFLRGPLRAGMPGNPIVGAQAGMGPMNPAMAGGTAGIGTAGGGAVMGAQGMGTGGMMGAQQTAQGQQGAGGIMNQTTPAMMGTTGGSIMSQSGGSMIQTGMMNPQQNPALVGQGMGGSGGLGGASGMAGNSGMGASASGMGGTSGGGMVTSGGMVTGGMGSAGIGNTAPMGAGAQGGGMGGNAGMPNAAGMGNPAMGNPGMGMQNMQQSGNMQGGGMFQGQNVPYQNVNQNYPNYGNQGMGQQSGQGGGMMGNFNPMAQQQRNTQAEFLAQQRAAMAAGRGQYGQHAPNVTMGNMGVNQGAVPPYPRQGGKPGVGGNMPQNQQQQFQQQRMRLIMQQHSGMGQGGNAQGMMQNQGQGMSTQQTPNLVAQLQRQMPNQNNMMGQQYPHQPPQY
Length2841
PositionKinase
OrganismAnopheles merus (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.05
Grand average of hydropathy-0.649
Instability index57.59
Isoelectric point6.84
Molecular weight311217.12
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08159
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     262.27|      18|      18|    2023|    2040|       1
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 2013- 2030 (40.12/ 9.03)	QQMQQMQQQQ.QQQQQQQQ
 2031- 2048 (41.70/ 9.69)	QQQQQQHQQH.QQQQQQQQ
 2082- 2098 (33.77/ 6.39)	LQQQQQLQQ..LQQQQQQQ
 2220- 2236 (41.15/ 9.46)	QQQQQQ.QQQ.QQQQQQQQ
 2301- 2319 (38.80/ 8.48)	QQQQQQQQQQqQQQQQQQQ
 2320- 2333 (33.20/ 6.15)	QQQQQQQQQQ.....QQQQ
 2428- 2445 (33.53/ 6.28)	SFMQQQQQQQ.QQQQQAQR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     729.24|      97|      99|    2640|    2737|       2
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 2121- 2200 (67.50/12.77)	.........P......QQQQSA....................LQQQqlGSQQ.G....QQQqqqqvtmtP....QQTLQQM.....QNNS.................MGGMQ........MGG...P..M...SsmnqQHMQQQYG.....QANPaqlvgqgnM.GGM..............................
 2202- 2278 (60.41/10.75)	TGM...G.GL..gagmGGGMMNqqqqqqqqqqqqqqqqqqqpPQQQ..QPQQ......AQQ........A....QQAQQAQ.....QQQP............QGnpnM..........GFVGNVN.P..M...A....QL..........................................................
 2346- 2447 (82.86/17.41)	.........P......QQGQQA....................SQQQ..GPQQ.GPqqGAQQ........GpqtqQQLQQQQ.....QQQQmfYS.........G...MGQAT........MNRFDrP.qL...N....TNSKQALSNML.RSKLP........INAGH........pasfmqqqqqqqqqqqqaqrNP
 2458- 2529 (97.13/21.85)	AGMP..G.NPivgaqaGMGPMN....................PAMA..GGTA.GI..GTAG........G....GAV...........M.......GA....QG...MG.....TG..GMMGA.Q.Q..T...A....QGQQGA.GGIMNQTTPA........M..................................
 2530- 2618 (114.27/26.91)	.....MG.TT......G.G.SI....................MSQS.......GG..SMIQ.......tG....MMNPQQN............PALVG....QG...MGGSGGLGGasGMAGN.S.G..MgasA....SGMGGTSGGGMVTSGGM........VTGGMGSagIGNT....................AP
 2642- 2737 (175.77/47.42)	..NPaMG.NP......GMGMQN....................MQQS..GNMQ.GG..GMFQ........G....QNVPYQN.....VNQN..YPNYGN....QG...MGQQSGQGG..GMMGNFN.P..M...A....QQQRNTQAEFLAQQRAA........MAAGRGQ..YGQH....................AP
 2741- 2838 (131.31/32.19)	MGN..MGvNQ......GAVPPY....................PRQG..GKPGvGG..NMPQ........N....QQQQFQQqrmrlIMQQ..HSGMGQggnaQG...MMQNQGQ....GMSTQQT.PnlV...A....QLQRQ.....MPNQNNM........M....GQ..QYPH....................QP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.51|      15|      15|    1629|    1643|       7
---------------------------------------------------------------------------
 1629- 1643 (26.78/13.61)	SKHKDGNGGNNSSNN
 1645- 1659 (25.73/12.77)	SHNHGANSNSSVSSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.78|      13|      24|    1706|    1721|       8
---------------------------------------------------------------------------
 1706- 1721 (15.20/23.13)	LQNRdQSLetIGGIED
 1732- 1744 (24.57/17.35)	LQLR.YSL..VGGLFD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.26|      28|      28|    1751|    1778|       9
---------------------------------------------------------------------------
 1751- 1778 (46.31/32.62)	TSTTDW..AILFAQLISQGVIDLSNNSELF
 1779- 1808 (40.95/27.84)	TTTLDMlaTLIHSTLVSDSQTERDENKKLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.53|      11|      15|    1397|    1410|      10
---------------------------------------------------------------------------
 1397- 1408 (14.86/16.56)	GSGDLShILGTS
 1414- 1424 (20.67/ 7.06)	GNPDES.MLDVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.66|      17|      20|    1857|    1873|      17
---------------------------------------------------------------------------
 1857- 1873 (28.48/20.96)	GNKIAI...DSIE.KKNGLRL
 1874- 1894 (21.18/13.29)	GDKQRVsvwDLLEgHKNPAPL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.60|       9|      28|    1928|    1937|      20
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 1928- 1937 (15.05/12.20)	PSSyYYEPLP
 1959- 1967 (18.55/ 8.94)	PSS.DQSPAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08159 with Med12 domain of Kingdom Metazoa
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