<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08151

Description Uncharacterized protein
SequenceMMNPNHSGASRRPYSRGAVPRNRSRMPFSPHHSHHANRNHGGHNQSWYNKDMENSFNYGDSGSSPKESSFTYTSKSPPVQLHSPPIAGRPTAATILMPYGAADDGSINNRSQQIHRAGPSHIDRHRINMGGNSMQERNRHTMSASSIDRHLNHFEGPSNSTRGADLHGGGDARSVLSMDSMRNSRDNNGGARERFSPHYHPGGGSGGGGGSGGGNGSGPAGGSNQGSSPPYCPVDGIGGNGGIKSDSPSRKRRRVSSRLPSQSPPAAIWEQRRSPRNGGGMMSLMGTSGANGGGNGQGSNGGLGNHGMNGHHSMSQQQQQQQQQQQQPQSSQSGQQQQLVPPQLHHRDHPQPHHHHPMHHHHHHSQQQQQQQQQQQQQSHHHTNGGGSHLHPSSGGGLAAAVISQLQSHAHHPQGSPPIRRPRFHRDQQSQQQQQPQQQQQQQPQQQQRPWESLTQVFQQAPAAQAQHQHPASSLMVDINQVPVSLPLGHHHEQLWTYSAGPHISICSGHPAAPHLPPCQVHGVYSQPFAQTCGIGGHFGGFASSAGPALAVPHPPPHQAHYQHPHLAQQRTDGLTLDGLEHAGGSPLHLSPLATHAHHLHGASPQMTQLTAAAQPIYISTEVSAVGSEVPRTGVTPAGTLIPLIANVPQGRNYEILHRTVRRAITAPRRNFARFHWPGPPPPPPPPPPPAHHQHHHPGHHPTHHHRPHAPPPPAALQAHPQPLGHPQPAHVTLSATTSAYSGILLNFLAMFPLSSYGPPDLNSPDSNETENYEALLSLAERLGEAKPRGLARPEIDQLPSYKFNAETHTGDQTSCVVCMCDFEARQILRVLPCSHEFHAKCVDKWLRSNRTCPICRGNASEYFESSEEQ
Length870
PositionKinase
OrganismAnopheles merus (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.05
Grand average of hydropathy-0.953
Instability index70.62
Isoelectric point9.39
Molecular weight94280.54
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
metal ion binding	GO:0046872	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08151
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     374.10|      45|      49|     297|     341|       1
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  183-  228 (47.97/ 9.06)	NSRDNN....GGARERF.........SPhyhpgGGSGGGGG........SGGGNG...................S.GPAGG.SNQGSS
  297-  326 (47.77/ 8.99)	.................................QGSNGGLG........NHGMNGHHS...............MS.QQQQQ.QQQQQQ
  327-  376 (75.01/18.63)	QPQSSQ....SGQQQQL.........VPpqlhhRDHPQPHH........HHPMHHHHH...............HS.QQQQQ.QQQQQQ
  377-  442 (42.46/ 7.11)	Q.QSHH..htNGGGSHL.........HP......SSGGGLAaavisqlqSH...AHHPqgsppirrprfhrdqQS.QQQQQpQQQQQQ
  517-  555 (54.70/11.44)	PPCQVH....GVY.SQ...........P.....FAQTCGIG...........GHFGGF...............AS.SAGPA.LAVPHP
  556-  614 (42.26/ 7.04)	PPHQAHyqhpHLAQQRTdgltldgleHA.....GGSPLHLS........PLATHAHHL...............HGaSPQMT.QLTAAA
  688-  721 (63.92/14.70)	PPPAHH........QHH.........HP............G........HHPTHHHRP...............HA.PPPPA.ALQAHP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     129.36|      30|     126|      98|     127|       2
---------------------------------------------------------------------------
   24-   67 (33.67/10.53)	SR..MPF..SPHHSHHanrnhgghnqswynkdmeNSF...........NYG....DSGSSPKE
   68-  110 (33.02/10.17)	SSftYTSKSPPVQLHS..................PPIagrptaatilmPYGAA..DDGSINNR
  111-  137 (35.93/11.80)	SQ..QIHRAGPSHIDR..................HRI................nmGGNSMQER
  257-  280 (26.75/ 6.65)	SR..LPSQSPPAAIWE..................QRR..........sPRNGG..G.......
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.52|      28|      31|     735|     765|       3
---------------------------------------------------------------------------
  735-  765 (37.46/36.77)	SATTSAYSGiLLNfLAMfPLSSYGPPDLNSP
  767-  794 (48.06/29.73)	SNETENYEA.LLS.LAE.RLGEAKPRGLARP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.81|      14|      32|       3|      16|       4
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    3-   16 (27.28/13.51)	NPNHSGASRRPYSR
   37-   50 (29.53/15.34)	NRNHGGHNQSWYNK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      82.19|      17|      19|     446|     462|       5
---------------------------------------------------------------------------
  446-  462 (31.65/15.16)	QQQRPWE.......SLTQVFQQAP
  467-  483 (28.11/12.57)	QHQHPAS.......SLMVDINQVP
  491-  514 (22.44/ 8.42)	HHEQLWTysagphiSICSGHPAAP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08151 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSPLHLSPLATHAHHLHGASPQMTQLTAAAQP
2) MMNPNHSGASRRPYSRGAVPRNRSRMPFSPHHSHHANRNHGGHNQSWYNKDMENSFNYGDSGSSPKESSFTYTSKSPPVQLHSPPIAGRPTAATILMPYGAADDGSINNRSQQIHRAGPSHIDRHRINMGGNSMQERNRHTMSASSIDRHLNHFEGPSNSTRGADLHGGGDARSVLSMDSMRNSRDNNGGARERFSPHYHPGGGSGGGGGSGGGNGSGPAGGSNQGSSPPYCPVDGIGGNGGIKSDSPSRKRRRVSSRLPSQSPPAAIWEQRRSPRNGGGMMSLMGTSGANGGGNGQGSNGGLGNHGMNGHHSMSQQQQQQQQQQQQPQSSQSGQQQQLVPPQLHHRDHPQPHHHHPMHHHHHHSQQQQQQQQQQQQQSHHHTNGGGSHLHPSSGGGLAAAVISQLQSHAHHPQGSPPIRRPRFHRDQQSQQQQQPQQQQQQQPQQQQRPWESLTQVFQQAPAAQAQHQHPASSLMVDINQVPV
3) PRRNFARFHWPGPPPPPPPPPPPAHHQHHHPGHHPTHHHRPHAPPPPAALQAHPQPLGHPQPAHVTLSA
4) SAGPALAVPHPPPHQAHYQHPHLAQQRTDGLTLDGLEHA
585
1
668
545
616
484
736
583










Molecular Recognition Features






MoRF SequenceStartStop




NANANA