<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08146

Description Mediator of RNA polymerase II transcription subunit 30
SequenceMAGQFPGGYQSPSGHRGNYNSPIIQQHLNQMNVPNQMGMMGFNQNNMMNSPQMQGVPGQGNQDMGLNPGMMQQNQQQQQPGQGMQPNPQQVATNQHQPGANQMVGQNPTHQAAQPSPQMGMQQQQQQQQQQQQQQQQQQQQQQQSSNVGPGNPMNNPQSQNQSVPPNQPGAGTAVQQQQKAEFNLLSLCRIGQETVQDIVSRFQEVFGILRSIQPPNGTNQGQLSSNDKKAKVQEQFRTIRLLFKRLRLLYDKCNDNCQQGMEYTHVESLIPLKGELERTEPVHTEEYKKALQENRELVAMVQLKNKQLREIIDKIRLTIWEINTMLSMRRC
Length332
PositionHead
OrganismAnopheles merus (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.04
Grand average of hydropathy-1.069
Instability index58.23
Isoelectric point9.08
Molecular weight37644.86
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08146
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     258.66|      48|      49|      67|     115|       1
---------------------------------------------------------------------------
    3-   46 (55.31/12.21)	.GQFPGGYQ.SPSGHR......GN.YNSPIIQQHL..NQMNVP.....nqmGMMGFNQ..NN..
   47-   81 (58.04/13.20)	..MMNSPQM....QGV......PGqGNQDMGLN..............P...GMMQQNQQQQQPG
   82-  132 (86.44/25.55)	QGMQPNPQQvATNQHQ......PG.ANQMVGQNPT..HQAAQPspQ.M...GMQQQQQQQQQQQ
  133-  182 (58.87/13.50)	QQ.QQQQQQ....QQQqssnvgPG..NPM..NNPQsqNQSVPP..NqP...GAGTAVQQQQKAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.68|      51|      66|     189|     249|       2
---------------------------------------------------------------------------
  188-  248 (72.36/52.32)	L........CRIGQETVQdiVSRFQEVFGILRSIQPpngtnqgqLSSNDKKAKVQEQ...FRTIRLLFKRLR
  249-  310 (73.31/34.97)	LlydkcndnCQQGMEYTH..VESLIPLKGELERTEP........VHTEEYKKALQENrelVAMVQLKNKQLR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08146 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MAGQFPGGYQSPSGHRGNYNSPIIQQHLNQMNVPNQMGMMGFNQNNMMNSPQMQGVPGQGNQDMGLNPGMMQQNQQQQQPGQGMQPNPQQVATNQHQPGANQMVGQNPTHQAAQPSPQMGMQQQQQQQQQQQQQQQQQQQQQQQSSNVGPGNPMNNPQSQNQSVPPNQPGAGTAVQQ
1
177










Molecular Recognition Features






MoRF SequenceStartStop




NANANA